mevalonolactone

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2H-pyran-2-one, tetrahydro-4-hydroxy-4-methyl-

CAS: 674-26-0 C6 H10 O3 MW: 130.14330000
All Ingredients Aromatic Ingredients CAS Numbers EINECS Numbers Found in Nature M.W Index

Identification

Namemevalonolactone
IUPAC4-hydroxy-4-methyloxan-2-one
CAS Number674-26-0
EINECS211-615-0
FDA UNII1RJ06DC41B
Molecular FormulaC6 H10 O3
Molecular Weight130.14330000
MDL NumberMFCD00006648
Nikkaji NumberJ38.600F
Beilstein080960
XlogP3-0.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshumectants

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for mevalonolactone usage levels up tonot for fragrance use.
Recommendation for mevalonolactone flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

4- hydroxy-4-methyloxan-2-one mevalonic acid lactone DL- mevalonic acid lactone mevalonolactone, (+/-)- 2H- pyran-2-one, tetrahydro-4-hydroxy-4-methyl- tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one (1)- tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one PubMed: Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells. PubMed: Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies. PubMed: Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols. PubMed: CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase. PubMed: New types of antimicrobial compounds produced by Lactobacillus plantarum. PubMed: A sensitive and selective method for the determination of mevalonic acid in dog plasma by gas chromatography/negative ion chemical ionization-mass spectrometry. PubMed: Singlet oxygen and peroxyl radicals regulate carotenoid biosynthesis in Phaffia rhodozyma.