camphoric acid

1,2,2-trimethyl-1,3-cyclopentanedicarboxylic acid

CAS: 5394-83-2 C10 H16 O4 MW: 200.23432000

Identification

Namecamphoric acid
CAS Number5394-83-2
EINECS226-404-9
FDA UNII32K0C7JGCJ
Molecular FormulaC10 H16 O4
Molecular Weight200.23432000
MDL NumberMFCD00066163
Nikkaji NumberJ139.252B

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 186.00 to 188.00 °C. @ 760.00 mm Hg
Boiling Point 311.00 to 312.00 °C. @ 760.00 mm Hg (est)
Flash Point 314.00 °F. TCC ( 156.70 °C. ) (est)
logP (o/w) 1.335 (est)
Soluble in water, 3400mg/L @ 20 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for camphoric acid usage levels up tonot for fragrance use.
Recommendation for camphoric acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1,2,2- trimethyl cyclopentane-1,3-dicarboxylic acid 1,2,2- trimethyl-1,3-cyclopentane dicarboxylic acid cis-1,2,2- trimethyl-1,3-cyclopentane dicarboxylic acid 1,2,2- trimethyl-1,3-cyclopentanedicarboxylic acid 1,2,2- trimethylcyclopentane-1,3-dicarboxylic acid PubMed: Coligand-directed synthesis of five Co(II)/Ni(II) coordination polymers with a neutral tetradentate ligand: syntheses, crystal structures, and properties. PubMed: Oriented circular dichroism analysis of chiral surface-anchored metal-organic frameworks grown by liquid-phase epitaxy and upon loading with chiral guest compounds. PubMed: Chiral metal-organic framework used as stationary phases for capillary electrochromatography. PubMed: Evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method. PubMed: Binary co-crystals of the active pharmaceutical ingredient 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene and camphoric acid. PubMed: Spontaneous resolution to absolute chiral induction: pseudo-Kagomé type homochiral Zn(II)/Co(II) coordination polymers with achiral precursors. PubMed: Three-dimensional homochiral manganese-lanthanide frameworks based on chiral camphorates with multi-coordination modes. PubMed: A 3-D open-framework material with intrinsic chiral topology used as a stationary phase in gas chromatography. PubMed: Chiral gels derived from secondary ammonium salts of (1R,3S)-(+)-camphoric acid. PubMed: [Preparation and spectroscopy properties of Eu2 (CA)3 (phen)2 doped Eu3+/TiO2 nano-powders]. PubMed: Multifunctional homochiral lanthanide camphorates with mixed achiral terephthalate ligands. PubMed: Progresses in TCM metal-based antitumour agents. PubMed: Synthesis of (1R,4S,6R)-5,5,6-trimethyl-2-phosphabicyclo[2.2.2]octane and derivatives. PubMed: Ultrasound-mediated synthesis of camphoric acid-based chiral salens for the enantioselective trimethylsilylcyanation of aldehydes. PubMed: Alteration of molecular conformations, coordination modes, and architectures for a novel 3,8-diimidazol-1,10-phenanthroline compound in the construction of cadmium(II) and zinc(II) homochiral coordination polymers involving an auxiliary chiral camphorate ligand. PubMed: Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. PubMed: Ionothermal synthesis of homochiral framework with acetate-pillared cobalt-camphorate architecture. PubMed: Three-dimensional homochiral transition-metal camphorate architectures directed by a flexible auxiliary ligand. PubMed: In Situ Synthesis of Tetradentate Dye for Construction of Three-Dimensional Homochiral Phosphor. PubMed: Assembly of a homochiral, body-centered cubic network composed of vertex-shared Mg12 cages: use of electrospray ionization mass spectrometry to monitor metal carboxylate nucleation. PubMed: Chiral magnetic metal-organic frameworks of dimetal subunits: magnetism tuning by mixed-metal compositions of the solid solutions. PubMed: [Synthesis and luminescence properties of europium (III ) complexes with camphoric acid and 1,10-phenanthroline]. PubMed: (1R,3S)-Camphoric acid as a building block in supramolecular chemistry: adducts with organic polyamines. PubMed: (1R,3S)-Camphoramic acid. PubMed: Reinvestigation of the reactions of camphorketene: structural evidence for pseudopericyclic pathways. PubMed: 1:1 hetero-assembly of 2-aminopyrimidine and (+)-camphoric acid PubMed: Troger's base molecular scaffolds in dicarboxylic acid recognition. PubMed: Quantitation and validation of cis-camphoric acid 3-methyl ester and cis-camphoric acid 1-methyl ester using CE. PubMed: Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands. PubMed: [Clinical evaluation of a new choleretic administered in normal and high doses to patients with chronic hepatocholecytopathies]. PubMed: [Double-blind clinical evaluation of choleretic agents in patients with chronic liver disease and cholestasis syndromes]. PubMed: [Mechanism of the hepato-biliary analeptic action of the phenyl-n-amylic monoester of camphoric acid]. PubMed: [CLINICAL EVALUATION OF A NEW PRODUCT WITH CHOLERETIC ACTION: THE SODIUM SALT OF PHENYL-N-AMYLIC MONOESTER OF CAMPHORIC ACID]. PubMed: [CONTRIBUTION TO CLINICAL EVALUATION OF A NEW SYNTHETIC CHOLERETIC (THE SODIUM SALT OF PENYL-N-AMYLIC MONOESTER OF CAMPHORIC ACID)]. PubMed: [CLINICAL FINDINGS ON THE THERAPEUTIC ACTIVITY OF A NEW SYNTHETIC CHOLERETIC: THE SODIUM SALT OF THE PHENYL-N-AMYL MONOESTER OF CAMPHORIC ACID]. PubMed: [ON THE SODIUM SLAT OF THE PHENYL-N-AMYL MONOESTER OF CAMPHORIC ACID IN THERAPY OF HABITUAL CHRONIC CONSTIPATION]. PubMed: A CLINICAL EVALUATION OF DIETHANOLAMINE SALT OF P-TOLYLMETHYLCARBINOL CAMPHORIC ACID (GALLOGEN) IN ARTERIOSCLEROSIS OBLITERANS. PubMed: [Influence of the effect of certain ganglion-blocking agents by gamma-methyl amide of camphoric acid]. PubMed: [Pharmacological properties of certain hypotensive camphoric acid derivatives]. PubMed: [Pharmacological study of the prophenamine salt of the 1-(p-tolyl)-ethyl monoester of d-camphoric acid].