camphoric acid
1,2,2-trimethyl-1,3-cyclopentanedicarboxylic acid
Identification
| Name | camphoric acid |
| CAS Number | 5394-83-2 |
| EINECS | 226-404-9 |
| FDA UNII | 32K0C7JGCJ |
| Molecular Formula | C10 H16 O4 |
| Molecular Weight | 200.23432000 |
| MDL Number | MFCD00066163 |
| Nikkaji Number | J139.252B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 186.00 to 188.00 °C. @ 760.00 mm Hg |
| Boiling Point | 311.00 to 312.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 314.00 °F. TCC ( 156.70 °C. ) (est) |
| logP (o/w) | 1.335 (est) |
| Soluble in | water, 3400mg/L @ 20 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for camphoric acid usage levels up to | not for fragrance use. |
| Recommendation for camphoric acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
1,2,2-
trimethyl cyclopentane-1,3-dicarboxylic acid
1,2,2-
trimethyl-1,3-cyclopentane dicarboxylic acid
cis-1,2,2-
trimethyl-1,3-cyclopentane dicarboxylic acid
1,2,2-
trimethyl-1,3-cyclopentanedicarboxylic acid
1,2,2-
trimethylcyclopentane-1,3-dicarboxylic acid
PubMed:
Coligand-directed synthesis of five Co(II)/Ni(II) coordination polymers with a neutral tetradentate ligand: syntheses, crystal structures, and properties.
PubMed:
Oriented circular dichroism analysis of chiral surface-anchored metal-organic frameworks grown by liquid-phase epitaxy and upon loading with chiral guest compounds.
PubMed:
Chiral metal-organic framework used as stationary phases for capillary electrochromatography.
PubMed:
Evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method.
PubMed:
Binary co-crystals of the active pharmaceutical ingredient 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene and camphoric acid.
PubMed:
Spontaneous resolution to absolute chiral induction: pseudo-Kagomé type homochiral Zn(II)/Co(II) coordination polymers with achiral precursors.
PubMed:
Three-dimensional homochiral manganese-lanthanide frameworks based on chiral camphorates with multi-coordination modes.
PubMed:
A 3-D open-framework material with intrinsic chiral topology used as a stationary phase in gas chromatography.
PubMed:
Chiral gels derived from secondary ammonium salts of (1R,3S)-(+)-camphoric acid.
PubMed:
[Preparation and spectroscopy properties of Eu2 (CA)3 (phen)2 doped Eu3+/TiO2 nano-powders].
PubMed:
Multifunctional homochiral lanthanide camphorates with mixed achiral terephthalate ligands.
PubMed:
Progresses in TCM metal-based antitumour agents.
PubMed:
Synthesis of (1R,4S,6R)-5,5,6-trimethyl-2-phosphabicyclo[2.2.2]octane and derivatives.
PubMed:
Ultrasound-mediated synthesis of camphoric acid-based chiral salens for the enantioselective trimethylsilylcyanation of aldehydes.
PubMed:
Alteration of molecular conformations, coordination modes, and architectures for a novel 3,8-diimidazol-1,10-phenanthroline compound in the construction of cadmium(II) and zinc(II) homochiral coordination polymers involving an auxiliary chiral camphorate ligand.
PubMed:
Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression.
PubMed:
Ionothermal synthesis of homochiral framework with acetate-pillared cobalt-camphorate architecture.
PubMed:
Three-dimensional homochiral transition-metal camphorate architectures directed by a flexible auxiliary ligand.
PubMed:
In Situ Synthesis of Tetradentate Dye for Construction of Three-Dimensional Homochiral Phosphor.
PubMed:
Assembly of a homochiral, body-centered cubic network composed of vertex-shared Mg12 cages: use of electrospray ionization mass spectrometry to monitor metal carboxylate nucleation.
PubMed:
Chiral magnetic metal-organic frameworks of dimetal subunits: magnetism tuning by mixed-metal compositions of the solid solutions.
PubMed:
[Synthesis and luminescence properties of europium (III ) complexes with camphoric acid and 1,10-phenanthroline].
PubMed:
(1R,3S)-Camphoric acid as a building block in supramolecular chemistry: adducts with organic polyamines.
PubMed:
(1R,3S)-Camphoramic acid.
PubMed:
Reinvestigation of the reactions of camphorketene: structural evidence for pseudopericyclic pathways.
PubMed:
1:1 hetero-assembly of 2-aminopyrimidine and (+)-camphoric acid
PubMed:
Troger's base molecular scaffolds in dicarboxylic acid recognition.
PubMed:
Quantitation and validation of cis-camphoric acid 3-methyl ester and cis-camphoric acid 1-methyl ester using CE.
PubMed:
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.
PubMed:
[Clinical evaluation of a new choleretic administered in normal and high doses to patients with chronic hepatocholecytopathies].
PubMed:
[Double-blind clinical evaluation of choleretic agents in patients with chronic liver disease and cholestasis syndromes].
PubMed:
[Mechanism of the hepato-biliary analeptic action of the phenyl-n-amylic monoester of camphoric acid].
PubMed:
[CLINICAL EVALUATION OF A NEW PRODUCT WITH CHOLERETIC ACTION: THE SODIUM SALT OF PHENYL-N-AMYLIC MONOESTER OF CAMPHORIC ACID].
PubMed:
[CONTRIBUTION TO CLINICAL EVALUATION OF A NEW SYNTHETIC CHOLERETIC (THE SODIUM SALT OF PENYL-N-AMYLIC MONOESTER OF CAMPHORIC ACID)].
PubMed:
[CLINICAL FINDINGS ON THE THERAPEUTIC ACTIVITY OF A NEW SYNTHETIC CHOLERETIC: THE SODIUM SALT OF THE PHENYL-N-AMYL MONOESTER OF CAMPHORIC ACID].
PubMed:
[ON THE SODIUM SLAT OF THE PHENYL-N-AMYL MONOESTER OF CAMPHORIC ACID IN THERAPY OF HABITUAL CHRONIC CONSTIPATION].
PubMed:
A CLINICAL EVALUATION OF DIETHANOLAMINE SALT OF P-TOLYLMETHYLCARBINOL CAMPHORIC ACID (GALLOGEN) IN ARTERIOSCLEROSIS OBLITERANS.
PubMed:
[Influence of the effect of certain ganglion-blocking agents by gamma-methyl amide of camphoric acid].
PubMed:
[Pharmacological properties of certain hypotensive camphoric acid derivatives].
PubMed:
[Pharmacological study of the prophenamine salt of the 1-(p-tolyl)-ethyl monoester of d-camphoric acid].