dibenzyl
1,1'-(1,2-ethanediyl)bisbenzene
Identification
| Name | dibenzyl |
| IUPAC | phenethylbenzene |
| CAS Number | 103-29-7 |
| EINECS | 203-096-4 |
| FDA UNII | 007C07V77Z |
| Molecular Formula | C14 H14 |
| Molecular Weight | 182.26558000 |
| MDL Number | MFCD00004796 |
| Nikkaji Number | J5.013J |
| Beilstein | 0508068 |
| XlogP3 | 4.80 (est) |
Regulatory
Physical Properties
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 52.50 °C. @ 760.00 mm Hg |
| Boiling Point | 284.00 °C. @ 760.00 mm Hg, 136.00 to 137.00 °C. @ 10.00 mm Hg |
| Vapor Pressure | 0.006000 mmHg @ 25.00 °C. (est) |
| Flash Point | 230.00 °F. TCC ( 110.00 °C. ) |
| logP (o/w) | 4.790 |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-rat LD50 4518 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 > 5000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for dibenzyl usage levels up to | 8.0000 % in the fragrance concentrate. |
| Recommendation for dibenzyl flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzene, 1,1'-(1,2-ethanediyl)bis-
dihydrostilbene
1,2-
dihydrostilbene
1,2-
diphenyl ethane
S-
diphenyl ethane
diphenylethane
1,2-
diphenylethane
1,1'-
ethan-1,2-diyldibenzol
1,1'-(1,2-
ethane diyl) bisbenzene
1,1'-
ethane-1,2-diyldibenzene
ethane, 1,2-diphenyl-
1,1'-(1,2-
ethanediyl)bisbenzene
1,1'-(1,2-
ethanediyl)dibenzene
phenethylbenzene
(2-
phenylethyl)benzene
PubMed:
Potent microbial and tyrosinase inhibitors from stem bark of Bauhinia rufescens (Fabaceae).
PubMed:
A pair of chiral fluorescent sensors for enantioselective recognition of mandelate in water.
PubMed:
Ground state conformational preferences and CH stretch-bend coupling in a model alkoxy chain: 1,2-diphenoxyethane.
PubMed:
Towards a first-principles model of Fermi resonance in the alkyl CH stretch region: application to 1,2-diphenylethane and 2,2,2-paracyclophane.
PubMed:
Symmetric kv1.5 blockers discovered by focused screening.
PubMed:
Verification of stereospecific dyotropic racemisation of enantiopure D and L-1,2-dibromo-1,2-diphenylethane in non-polar media.
PubMed:
Design, synthesis and molecular simulation studies of dihydrostilbene derivatives as potent tyrosinase inhibitors.
PubMed:
Conformational mobility of small molecules in glass-forming solutions studied by FTIR spectroscopy.
PubMed:
Theoretical study on the mechanism of Ni-catalyzed alkyl-alkyl Suzuki cross-coupling.
PubMed:
o-Carborane as an electron-transfer mediator in electrocatalytic reduction.
PubMed:
A recyclable organocatalyst for asymmetric Michael addition of acetone to nitroolefins.
PubMed:
Complete NMR data of methoxylated cis- and trans-stilbenes as well as 1,2-diphenylethanes.
PubMed:
Radical reactivity of aza[60]fullerene: preparation of monoadducts and limitations.
PubMed:
Lanthanide tri-benzyl complexes: structural variations and useful precursors to phosphorus-stabilised lanthanide carbenes.
PubMed:
Steric, geometrical and solvent effects on redox potentials in salen-type copper(II) complexes.
PubMed:
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants.
PubMed:
Enantioselective oxidation of sulfides catalyzed by titanium complexes of 1,2-diarylethane-1,2-diols: effect of the aryl substitution.
PubMed:
Supramolecular structures of bis-thionooxalamic acid esters derived from (+/-)-cyclohexane-1,2-diamine and (+/-)-1,2-diphenylethylenediamine.
PubMed:
Chiral bridged aminotroponiminate complexes of the lanthanides.
PubMed:
A para-hydrogen investigation of palladium-catalyzed alkyne hydrogenation.
PubMed:
The vicinal difluoro motif: The synthesis and conformation of erythro- and threo- diastereoisomers of 1,2-difluorodiphenylethanes, 2,3-difluorosuccinic acids and their derivatives.
PubMed:
Band shape determination with robust estimator based on continuous wavelet transform.
PubMed:
Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
PubMed:
Carbon-halogen bond activation mechanism by copper(I) complexes of (2-pyridyl)alkylamine ligands.
PubMed:
Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.
PubMed:
Some 1,2-diphenylethane derivatives as inhibitors of retinoic acid--metabolising enzymes.
PubMed:
A novel DI*A allele without the Band 3-Memphis mutation in Amazonian Indians.
PubMed:
Modeling the chromatographic enantioseparation of aryl- and hetarylcarbinols on ULMO, a brush-type chiral stationary phase, by 3D-QSAR techniques.
PubMed:
Synthesis of a new water-soluble C(2)-symmetric chiral diamine: preliminary investigation of its catalytic properties for asymmetric hydrogenation under biphasic conditions.
PubMed:
[(Indenyl)Ru(biphop-F)](+): A Lewis Acid Catalyst That Controls both the Diene and the Dienophile Facial Selectivity in Diels-Alder Reactions This work was supported by the Swiss National Science Foundation (FNS grant 20-59374.99) and The Ministère des Affaires Etrangères from France (Lavoisier grant to V.A.). biphop-F=1,2-bis[bis(pentafluorophenyl)phosphanyloxy]-1,2-diphenylethane.
PubMed:
An approach to a chiral cycloalkanone-mediated asymmetric epoxidation of stilbene with oxone.
PubMed:
Immobilization of difunctional building blocks on hydroxysuccinimide activated silica: versatile in situ preparation of chiral stationary phases.
PubMed:
meso-1,2-bis(methylazo)-1,2-diphenylethane.
PubMed:
Induction of Cholesteric Mesophases by Simple Cyclic Derivatives of p,p'-Disubstituted 1,2-Diphenylethane-1,2-diols: Importance of Shape and Polarizability Effects.
PubMed:
Alkyl bromides as mechanistic probes of reductive dehalogenation: reactions of vicinal dibromide stereoisomers with zerovalent metals.
PubMed:
Investigations of new lead structures for the design of selective estrogen receptor modulators.
PubMed:
Synthesis and stereochemical characterization of optically active 1,2-diarylethane-1,2-diols: useful chiral controllers in the Ti-mediated enantioselective sulfoxidation.
PubMed:
Evidence for a dinuclear mechanism in alkyne hydrogenations catalyzed by pyrazolate-bridged diiridium complexes
PubMed:
Analysis of leucine enkephalin by high-performance liquid chromatography using enzymatic derivatization by tyrosinase and electrochemical or fluorescence detection.
PubMed:
Modulation of clinical expression and band 3 deficiency in hereditary spherocytosis.
PubMed:
1,3-Diphenylpropane-1,3-diamines, VI): DNA-interaction, estrogen receptor affinity, and cytostatic activity of 1,3-diphenylpropane-1,3-diamine-Pt(II) complexes.
PubMed:
Oligomeric forms of skate erythrocyte band 3. Effect of volume expansion.
PubMed:
Two different mRNAs from rat liver code for the transport of bumetanide and taurocholate in Xenopus laevis oocytes.
PubMed:
Band 3 HT, a human red-cell variant associated with acanthocytosis and increased anion transport, carries the mutation Pro-868-->Leu in the membrane domain of band 3.
PubMed:
A red cell band 3 variant with altered stilbene disulphonate binding is associated with the Diego (Dia) blood group antigen.
PubMed:
A new fluorogenic assay for tyrosine-containing peptides.
PubMed:
Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2- phenylethylenediamine](sulfato)platinum-(II) complexes with variable substituents in the 2-phenyl ring. 1. Synthesis and antitumor and estrogenic properties.
PubMed:
Synthesis and anticonvulsant evaluation of 1,2-diphenylethane derivatives, potential metabolites of denzimol.
PubMed:
Low-density lipoprotein endocytosis. I. Influence of the multivalent ligand cationized ferritin on normal and receptor-negative human fibroblasts.
PubMed:
Evidence for glycoprotein components of the hepatocellular bile acid transporter.
PubMed:
Iodipamide uptake by rat liver plasma membrane vesicles enriched in the sinusoidal fraction: evidence for a carrier-mediated transport dependent on membrane potential.
PubMed:
Catabolism of the anion transport protein in human erythrocytes.
PubMed:
A new variant of the anion transport protein in human erythrocytes.
PubMed:
Anti-proliferative effects of 1,2-diphenylethane oestrogens and anti-oestrogens on human breast cancer cells.
PubMed:
Effects of the transport site conformation on the binding of external NAP-taurine to the human erythrocyte anion exchange system. Evidence for intrinsic asymmetry.
PubMed:
Further characterization of membrane proteins involved in the transport of organic anions in hepatocytes. Comparison of two different affinity labels: 4,4'-diisothiocyano-1,2-diphenylethane-2,2'-disulfonic acid and brominated taurodehydrocholic acid.
PubMed:
9,10-Dihydrophenanthrenes as phytoalexins of Orchidaceae. Biosynthetic studies in vitro and in vivo proving the route from L-phenylalanine to dihydro-m-coumaric acid, dihydrostilbene and dihydrophenanthrenes.
PubMed:
Inhibition of anion permeability of sarcoplasmic reticulum vesicles by stilbene derivatives and the identification of an inhibitor-binding protein.
PubMed:
Inhibition of Ehrlich ascites cell anion transport by 1-isothiocyanate-4-benzenesulfonic acid.
PubMed:
Adherence of bacteria to mammalian cells: inhibition by tunicamycin and streptovirudin.
PubMed:
Ehrlich ascites tumor cell surface labeling and kinetics of glycocalyx release.
PubMed:
Chloride and sulfate transport in Ehrlich ascites tumor cells: evidence for a common mechanism.
PubMed:
[Derivatives of 1-amino-1,2-diphenylethane].
PubMed:
[Retinal arteriolar spasmolysis; clinico-experimental study with nicotylamino-1, 2-diphenylethane (lyspamin)].