ginkgolide B

(1beta)-1-hydroxyginkgolide A

CAS: 15291-77-7 C20 H24 O10 MW: 424.40328000

Identification

Nameginkgolide B
CAS Number15291-77-7
FDA UNIIDF149B9460
Molecular FormulaC20 H24 O10
Molecular Weight424.40328000
MDL NumberMFCD05662347

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 762.00 to 763.00 °C. @ 760.00 mm Hg (est)
Flash Point 526.00 °F. TCC ( 274.30 °C. ) (est)
logP (o/w) 2.070 (est)
Soluble in water, 1.838e+005 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for ginkgolide B usage levels up tonot for fragrance use.
Recommendation for ginkgolide B flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

ginkgo biloba

Synonyms

11-tert- butyl-1,4b,8-trihydroxy-5-methyltetrahydro-4bh,9h-9,4a-(epoxymethano)cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1h,5h)-trione 8-tert- butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione 8-(tert- butyl)-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione ginkolide B (1beta)-1- hydroxyginkgolide A PubMed: A novel oil-body nanoemulsion formulation of ginkgolide B: pharmacokinetics study and in vivo pharmacodynamics evaluations. PubMed: Ginkgolide B prevents cathepsin-mediated cell death following cerebral ischemia/reperfusion injury. PubMed: Two new nonacosanetriols from Ginkgo biloba sarcotesta. PubMed: Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples. PubMed: Column liquid chromatography/electrospray ionization-time of flight-mass spectrometry and ultraperformance column liquid chromatography/mass spectrometry methods for the determination of ginkgolides and bilobalide in the leaves of Ginkgo biloba and dietary supplements. PubMed: In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves. PubMed: A method for extraction and quantification of Ginkgo terpene trilactones. PubMed: Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations. PubMed: Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice. PubMed: Selective responses of three Ginkgo biloba leaf-derived constituents on human intestinal bacteria. PubMed: Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts. PubMed: [Pharmacokinetic properties of Bilobalide and Ginkgolides A and B in healthy subjects after intravenous and oral administration of Ginkgo biloba extract (EGb 761)]. PubMed: Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics.