hinokiflavone

6-[4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-phenoxy]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one

CAS: 19202-36-9 C30 H18 O10 MW: 538.46546000

Identification

Namehinokiflavone
IUPAC6-[4-(5,7-dihydroxy-4-oxochromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
CAS Number19202-36-9
EINECS242-877-4
FDA UNIISearch
Molecular FormulaC30 H18 O10
Molecular Weight538.46546000
MDL NumberMFCD00017455
Nikkaji NumberJ13.600J
XlogP34.40 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 841.00 to 842.00 °C. @ 760.00 mm Hg (est)
Flash Point 545.00 °F. TCC ( 284.80 °C. ) (est)
logP (o/w) 5.528 (est)
Soluble in water, 0.03816 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for hinokiflavone usage levels up tonot for fragrance use.
Recommendation for hinokiflavone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

cupressus torulosa cone juniper rhus retinorrhoea leaf rhus succedanea sugi

Synonyms

4H-1- benzopyran-4-one, 6-[4-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- 4',6''- biapigenin 4',6''-O- biapigenin 6-(4-(5,7- dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-phenoxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone 6-(4-(5,7- dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone 6-[4-(5,7- dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone 6-[4-(5,7- dihydroxy-4-oxo-4H-chromen-2-yl)-phenoxy]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one 6-[4-(5,7- dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 6-[4-(5,7- dihydroxy-4-oxochromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one PubMed: Study of the hepatoprotective effect of Juniperus phoenicea constituents. PubMed: [Simultaneous determination of selaginellins and biflavones in Selaginella tamariscina and S. pulvinata by HPLC]. PubMed: Isolation and cytotoxic activity of selaginellin derivatives and biflavonoids from Selaginella tamariscina. PubMed: Selaginellin A and B, two novel natural pigments isolated from Selaginella tamariscina. PubMed: Structurally unique biflavonoids from Selaginella chrysocaulos and Selaginella bryopteris. PubMed: A new glucoside from Selaginella sinensis. PubMed: Biflavones from Chamaecyparis obtusa. PubMed: Antifungal biflavones from Cupressocyparis leylandii. PubMed: In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora. PubMed: [Chemical constitutents of Podocarpus imbricatus BI. (II)]. PubMed: Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids. PubMed: Flavonoids in the leaves of Juniperus drupacea. PubMed: Cryptomerin A and B, hinokiflavone methyl ethers from the leaves of Cryptomeria japonica. PubMed: Discovery of potent inhibitor for matrix metalloproteinase-9 by pharmacophore based modeling and dynamics simulation studies. PubMed: Study of the hepatoprotective effect of Juniperus phoenicea constituents. PubMed: [Simultaneous determination of selaginellins and biflavones in Selaginella tamariscina and S. pulvinata by HPLC]. PubMed: Isolation and cytotoxic activity of selaginellin derivatives and biflavonoids from Selaginella tamariscina. PubMed: Structural characterization and identification of biflavones in Selaginella tamariscina by liquid chromatography-diode-array detection/electrospray ionization tandem mass spectrometry. PubMed: Selaginellin A and B, two novel natural pigments isolated from Selaginella tamariscina. PubMed: Biflavones from Chamaecyparis obtusa. PubMed: Biflavonoids from Cycas beddomei. PubMed: Antifungal biflavones from Cupressocyparis leylandii. PubMed: Antiviral activities of biflavonoids. PubMed: [Chemical constitutents of Podocarpus imbricatus BI. (II)].