gentiakochianin
6-methoxy-1,2,8-trihydroxyxanthen-9-one
Identification
| Name | gentiakochianin |
| IUPAC | 1,2,8-trihydroxy-6-methoxyxanthen-9-one |
| CAS Number | 20882-75-1 |
| FDA UNII | 890WXQ4KC0 |
| Molecular Formula | C14 H10 O6 |
| Molecular Weight | 274.22890000 |
| MDL Number | MFCD01328726 |
| Nikkaji Number | J16.797E |
| Beilstein | 1351024 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 576.90 °C. @ 760.00 mm Hg (est) |
| Flash Point | 440.00 °F. TCC ( 226.70 °C. ) (est) |
| logP (o/w) | 1.350 (est) |
| Soluble in | water, 1.819 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for gentiakochianin usage levels up to | not for fragrance use. |
| Recommendation for gentiakochianin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
6-
methoxy-1,2,8-trihydroxyxanthen-9-one
swertianin
swertianine
1,2,8-
trihydroxy-6-methoxy-9H-xanthen-9-one
1,2,8-
trihydroxy-6-methoxyxanthen-9-one
9H-
xanthen-9-one, 1,2,8-trihydroxy-6-methoxy- (9CI)
xanthen-9-one, 6-methoxy-1,2,8-trihydroxy-
PubMed:
Evaluation of anticonvulsant, sedative, anxiolytic, and phytochemical profile of the methanol extract from the aerial parts of Swertia corymbosa (Griseb.) wight ex C.B. Clarke.
PubMed:
Anti-diabetic activity of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke aerial parts extract in streptozotocin induced diabetic rats.
PubMed:
Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae).
PubMed:
Antiglioma action of xanthones from Gentiana kochiana: Mechanistic and structure-activity requirements.
PubMed:
Neuropharmacological evaluation of diethylether extract and xanthones of Gentiana kochiana.
PubMed:
[Study on chemical constituents from Swertia kauitchensis Franch].
PubMed:
The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana.