carvone
DL-carvone
Identification
| Name | carvone |
| IUPAC | 2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one |
| CAS Number | 99-49-0 |
| EINECS | 202-759-5 |
| FDA UNII | 75GK9XIA8I |
| Molecular Formula | C10 H14 O |
| Molecular Weight | 150.22078000 |
| Nikkaji Number | J4.522E |
| Beilstein | 1364206 |
| CoE Number | 146 |
Regulatory
| JECFA Food Flavoring | 2245 carvone |
| DG SANTE Food Flavourings | 07.012 carvone |
| FEMA Number | 2249 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 99-49-0 ; CARVONE |
| FDA Regulation | FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 97.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 231.00 °C. @ 760.00 mm Hg, 137.00 to 138.00 °C. @ 50.00 mm Hg |
| Vapor Pressure | 0.160000 mmHg @ 25.00 °C. |
| Flash Point | 192.00 °F. TCC ( 88.89 °C. ) |
| logP (o/w) | 3.070 |
| Soluble in | alcohol |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | fragrance |
Organoleptic Properties
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | oral-rat LD50 1640 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 2675 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| IFRA Critical Effect | Dermal sensitization and systemic toxicity |
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%) | Category 1: Products applied to the lips |
| Notes | IFRA FLAVOR REQUIREMENTS: |
| baked goods | 94.00000 |
| beverages(nonalcoholic) | 34.00000 |
| beverages(alcoholic) | 126.00000 |
| breakfast cereal | - |
| cheese | 0.20000 |
| chewing gum | 10000.00000 |
| condiments / relishes | 50.00000 |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 150.00000 |
| fruit ices | - |
| gelatins / puddings | 87.00000 |
| granulated sugar | - |
| gravies | - |
| hard candy | 5000.00000 |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | 0.10000 |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | 5000.00000 |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
Axxence Aromatic GmbH
We bring nature to your flavour
Dedicated to provide the best possible quality and supply service of natural aroma ingredients.
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Jiangyin Healthway International Trade Co., Ltd
Independent Ingredients Supplier
We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
Lluch Essence S.L.
A family company dedicated to sales and distribution
Flexibility, availability, price and quality.
Potential Uses
Natural Occurrence
Synonyms
DL-
carvone
D-
carvone natural
2-
cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-
delta-p-
mentha-1(6),8-dien-2-one
delta-para-
mentha-1(6),8-dien-2-one
p-
mentha-6,8-dien-2-one
para-
mentha-6,8-dien-2-one
6,8(9)-p-
menthadien-2-one
delta-1-
methyl-4-isopropenyl-6-cyclohexen-2-one
2-
methyl-5-(1-methyl ethenyl)-2-cyclohexen-1-one
2-
methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one
2-
methyl-5-isopropenyl-2-cyclohexenone
2-
methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one
5-iso
propenyl-2-methyl-2-cyclohexen-1-one
delta(sup 6,8)-(9)-
terpadienone-2
PubMed:
Transfer of terpenes from essential oils into cow milk.
PubMed:
(-)-Carvone: antispasmodic effect and mode of action.
PubMed:
Chemical composition and biological activities of Calamintha officinalis Moench essential oil.
PubMed:
Allergic contact dermatitis from carvone in hair conditioners.
PubMed:
Chitosan coating improves retention and redispersibility of freeze-dried flavor oil emulsions.
PubMed:
Comparative analysis of essential oils from eight herbal medicines with pungent flavor and cool nature by GC-MS and chemometric resolution methods.
PubMed:
Enhanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic biocatalyst.
PubMed:
Chemical and physical stability of protein and gum arabic-stabilized oil-in-water emulsions containing limonene.
PubMed:
Inhibitory effects of substrate and product on the carvone biotransformation activity of Rhodococcus erythropolis.
PubMed:
Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions.
PubMed:
Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study.
PubMed:
Character impact odorants of fennel fruits and fennel tea.
PubMed:
Changes of the volatile profile and artifact formation in Daidai (Citrus aurantium) cold-pressed peel oil on storage.
PubMed:
Influence of drying on the flavor quality of spearmint (Mentha spicata L.).
PubMed:
Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells.
PubMed:
Volatile flavor components of ripe and overripe ki-mikans (Citrus flaviculpus Hort. ex Tanaka) in comparison with Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed:
Cinnamaldehyde content in foods determined by gas chromatography-mass spectrometry.
PubMed:
Aroma-active compounds of miniature beefsteakplant (Mosla dianthera Maxim).
PubMed:
Applications of High-Temperature Aqueous Media for Synthetic Organic Reactions.
PubMed:
Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings.
PubMed:
Conductive olfactory losses in chronic rhinosinusitis? A computational fluid dynamics study of 29 patients.
PubMed:
Perceptual and processing differences between physical and dichorhinic odor mixtures.
PubMed:
Rapid odor perception in rat olfactory bulb by microelectrode array.
PubMed:
Stress-related activities induced by predator odor may become indistinguishable by hinokitiol odor.
PubMed:
(-)-Carvone: antispasmodic effect and mode of action.
PubMed:
Olfactory discrimination ability of South African fur seals (Arctocephalus pusillus) for enantiomers.
PubMed:
Odor detection and odor discrimination in subadult and adult rats for two enantiomeric odorants supported by c-fos data.
PubMed:
[Characterization of aroma active compounds in blood orange juice by solid phase microextraction and gas chromatography-mass spectrometry-olfactometry].
PubMed:
Performance of mice in discrimination of liquor odors: behavioral evidence for olfactory attention.
PubMed:
Response accuracy and odor sampling time in mice trained to discriminate between enantiomers of carvone and those of terpinen-4-ol.
PubMed:
Character impact odorants of fennel fruits and fennel tea.
PubMed:
The number of functional olfactory receptor genes and the relative size of olfactory brain structures are poor predictors of olfactory discrimination performance with enantiomers.
PubMed:
Composition and aroma compounds of Ragusano cheese: native pasture and total mixed rations.
PubMed:
Olfactory discrimination ability of human subjects for enantiomers with an isopropenyl group at the chiral center.
PubMed:
OMP gene deletion results in an alteration in odorant-induced mucosal activity patterns.
PubMed:
Olfactory discrimination of short chain fatty acids in rats with large bilateral lesions of the olfactory bulbs.
PubMed:
Influence of drying on the flavor quality of spearmint (Mentha spicata L.).
PubMed:
Sensitivity-dependent hierarchical receptor codes for odors.
PubMed:
Concanavalin A application to the olfactory epithelium reveals different sensory neuron populations for the odour pair D- and L-carvone.
PubMed:
Spontaneous versus reinforced olfactory discriminations.
PubMed:
A psychophysical study of the relationship between temporal processing in odor mixtures and transduction pathways.
PubMed:
Enantioselectivity of odor perception in honeybees (Apis mellifera carnica).
PubMed:
Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation.
PubMed:
Relationships between odor-elicited oscillations in the salamander olfactory epithelium and olfactory bulb.
PubMed:
Enantioselectivity of odor perception in squirrel monkeys and humans.
PubMed:
Olfactory discrimination ability of human subjects for ten pairs of enantiomers.
PubMed:
Temporal processing of odor mixtures reveals that identification of components takes precedence over temporal information in olfactory memory.
PubMed:
Identification of ligands for olfactory receptors by functional expression of a receptor library.
PubMed:
Spatially organized response zones in rat olfactory epithelium.
PubMed:
Ca2+ and Cl(-)-dependence of the turtle olfactory response to odorants and forskolin.
PubMed:
Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings.
PubMed:
Temperature increase abolishes ability of turtle olfactory receptors to discriminate similar odorant.
PubMed:
A mass transport model of olfaction.
PubMed:
Differential olfactory perception of enantiomeric compounds by blind subterranean mole rats (Spalax ehrenbergi).
PubMed:
Quantitative analysis on odor intensity and quality of optical isomers in turtle olfactory system.
PubMed:
Olfactory bulb size, odor discrimination and magnetic insensitivity in hummingbirds.
PubMed:
Odor masking in the rat.
PubMed:
Sensory evidence for olfactory receptors with opposite chiral selectivity.
PubMed:
Quality and intensity of binary odor mixtures.
PubMed:
Odor incongruity and chirality.
PubMed:
Odor differences between enantiomeric isomers.
PubMed:
Study of chemical stability of lemon oil components in sodium caseinate-lactose glycoconjugate-stabilized oil-in-water emulsions using solid-phase microextraction-gas chromatography.