Identification

Namecarvone
IUPAC2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one
CAS Number99-49-0
EINECS202-759-5
FDA UNII75GK9XIA8I
Molecular FormulaC10 H14 O
Molecular Weight150.22078000
Nikkaji NumberJ4.522E
Beilstein1364206
CoE Number146

Regulatory

JECFA Food Flavoring2245 carvone
DG SANTE Food Flavourings07.012 carvone
FEMA Number2249
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)99-49-0 ; CARVONE
FDA RegulationFDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 231.00 °C. @ 760.00 mm Hg, 137.00 to 138.00 °C. @ 50.00 mm Hg
Vapor Pressure 0.160000 mmHg @ 25.00 °C.
Flash Point 192.00 °F. TCC ( 88.89 °C. )
logP (o/w) 3.070
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Oral/Parenteral Toxicityoral-rat LD50 1640 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 2675 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
IFRA Critical EffectDermal sensitization and systemic toxicity
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%)Category 1: Products applied to the lips
NotesIFRA FLAVOR REQUIREMENTS:
baked goods94.00000
beverages(nonalcoholic)34.00000
beverages(alcoholic)126.00000
breakfast cereal-
cheese0.20000
chewing gum10000.00000
condiments / relishes50.00000
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy150.00000
fruit ices-
gelatins / puddings87.00000
granulated sugar-
gravies-
hard candy5000.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products0.10000
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy5000.00000
soups-
sugar substitutes-
sweet sauces-

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

View All Website +49.2822.68561.0 service@axxence.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

Potential Uses

None Found

Natural Occurrence

agathosma crenulata oil @ 0.22% Data ajowan seed oil turkey @ trace% Data anise seed oil anise star anise fruit basil plant basil shoot oil bay laurel leaf bergamot oil @ 0.000-trace% Data bergamot oil @ 0.09% Data buchu leaf oil @ trace% Data cabbage leaf caraway oil caraway plant caraway seed caraway seed oil caraway seed oil @ 52.30-54.40% Data cardamom fruit oil carrot seed carrot weed oil @ 8.77% Data cascarilla bark oil @ 0.03% Data cayenne fruit celery leaf celery seed celery seed oil celery seed oil CO2 extract india @ 0.02% Data celery seed oil egypt @ 0.40% Data celery seed oil india @ 0.06% Data celery shoot cistus oil @ 0.5% Data clove plant coriander fruit cornmint leaf cornmint oil india @ 0.05% Data costmary oil @ 51.51% Data cubeb oil @ trace% Data cypress cone oil egypt @ trace% Data dill leaf dill leaf oil dill oil dill root dill seed dill seed oil dill shoot oil dill weed oil cuba @ 14.50% Data dill weed oil reunion @ 0.40% Data eucalyptus globulus bicostata oil @ 0.16% Data eucalyptus globulus maidenii f. muell oil @ 0.15% Data eucalyptus globulus pseudoglobulus oil @ 0.31% Data fennel seed oil fleabane oil @ 1.10% Data gingergrass oil @ 3.20% Data helichrysum arenarium (l.) moench oil hungary @ 1.10% Data horsemint shoot kewda oil @ trace% Data labdanum leaf oil @ 0.30% Data labdanum oil @ 0.31% Data laurel leaf oil turkey @ 0.10% Data lavandin oil china @ 0.12% Data lavandin oil grosso @ trace% Data lemon oil lemon verbena oil morocco @ 0.8% Data lemon verbena oil turkey @ 0.50% Data levisticum officinale flower oil @ 0.27% Data levisticum officinale seed oil @ 0.10% Data lime oil distilled mexico @ 0.01% Data lime oil distilled peru @ trace% Data lovage root mandarin fruit mandarin oil @ 0.20% Data mandarin oil uruguay @ 0.02-0.07% Data marjoram oil marjoram oil sweet cyprus @ 0.00-0.70% Data marjoram oil sweet turkey @ 0.15-0.17% Data marjoram plant mastic fruit oil @ 1.32% Data mikan peel oil @ trace% Data myrtle oil @ 0.08% Data nepeta denudata benth. oil iran @ 0.40% Data orange fruit orange peel oil bitter china @ 0.03% Data oregano plant oregano plant oregano shoot osmanthus absolute @ trace% Data pennyroyal oil uruguay @ 0.20-2.20% Data pepper black pepper fruit pepper black pepper fruit oil peppermint leaf peppermint oil mongolia @ 0.16% Data pimenta leaf oil @ 0.10% Data plum fruit rosemary leaf rosemary oil CO2 extract @ 0.26% Data rosemary oil egypt @ 1.67% Data rosemary plant rugula herb sage oil cuba @ 0.21% Data sage oil spain @ 0.0-0.3% Data salvia officinalis oil cuba @ 0.21% Data savory winter savory plant spearmint oil america @ 65.79-71.62% Data spearmint plant tansy flower oil canada @ 0.84% Data tansy oil canada @ 6.60% Data tansy oil marocco @ 0.30% Data tarragon plant thyme absolute @ trace% Data thyme plant thymus richardii pers. subsp. nitidus (guss.) jalas oil italy @ 0.70% Data trachyspermum roxburghianum benth. ex. kurz. seed oil india @ trace% Data tsauri grass oil @ 4.10% Data turmeric root oil CO2 extract @ 2.12% Data water mint leaf wormseed oil america @ 2.28% Data wormseed oil spain @ 0.2% Data wormseed oil spain @ 2.07% Data wormwood oil italy @ trace% Data yarrow leaf oil @ trace% Data yuzu peel oil c.p. @ 0.01-0.02% Data yuzu peel oil CO2 extract @ 0.01% Data zingiber officinale root oil china @ 0.26% Data

Synonyms

DL- carvone D- carvone natural 2- cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)- delta-p- mentha-1(6),8-dien-2-one delta-para- mentha-1(6),8-dien-2-one p- mentha-6,8-dien-2-one para- mentha-6,8-dien-2-one 6,8(9)-p- menthadien-2-one delta-1- methyl-4-isopropenyl-6-cyclohexen-2-one 2- methyl-5-(1-methyl ethenyl)-2-cyclohexen-1-one 2- methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one 2- methyl-5-isopropenyl-2-cyclohexenone 2- methyl-5-prop-1-en-2-ylcyclohex-2-en-1-one 5-iso propenyl-2-methyl-2-cyclohexen-1-one delta(sup 6,8)-(9)- terpadienone-2 PubMed: Transfer of terpenes from essential oils into cow milk. PubMed: (-)-Carvone: antispasmodic effect and mode of action. PubMed: Chemical composition and biological activities of Calamintha officinalis Moench essential oil. PubMed: Allergic contact dermatitis from carvone in hair conditioners. PubMed: Chitosan coating improves retention and redispersibility of freeze-dried flavor oil emulsions. PubMed: Comparative analysis of essential oils from eight herbal medicines with pungent flavor and cool nature by GC-MS and chemometric resolution methods. PubMed: Enhanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic biocatalyst. PubMed: Chemical and physical stability of protein and gum arabic-stabilized oil-in-water emulsions containing limonene. PubMed: Inhibitory effects of substrate and product on the carvone biotransformation activity of Rhodococcus erythropolis. PubMed: Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions. PubMed: Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study. PubMed: Character impact odorants of fennel fruits and fennel tea. PubMed: Changes of the volatile profile and artifact formation in Daidai (Citrus aurantium) cold-pressed peel oil on storage. PubMed: Influence of drying on the flavor quality of spearmint (Mentha spicata L.). PubMed: Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells. PubMed: Volatile flavor components of ripe and overripe ki-mikans (Citrus flaviculpus Hort. ex Tanaka) in comparison with Hyuganatsu (Citrus tamurana Hort. ex Tanaka). PubMed: Cinnamaldehyde content in foods determined by gas chromatography-mass spectrometry. PubMed: Aroma-active compounds of miniature beefsteakplant (Mosla dianthera Maxim). PubMed: Applications of High-Temperature Aqueous Media for Synthetic Organic Reactions. PubMed: Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings. PubMed: Conductive olfactory losses in chronic rhinosinusitis? A computational fluid dynamics study of 29 patients. PubMed: Perceptual and processing differences between physical and dichorhinic odor mixtures. PubMed: Rapid odor perception in rat olfactory bulb by microelectrode array. PubMed: Stress-related activities induced by predator odor may become indistinguishable by hinokitiol odor. PubMed: (-)-Carvone: antispasmodic effect and mode of action. PubMed: Olfactory discrimination ability of South African fur seals (Arctocephalus pusillus) for enantiomers. PubMed: Odor detection and odor discrimination in subadult and adult rats for two enantiomeric odorants supported by c-fos data. PubMed: [Characterization of aroma active compounds in blood orange juice by solid phase microextraction and gas chromatography-mass spectrometry-olfactometry]. PubMed: Performance of mice in discrimination of liquor odors: behavioral evidence for olfactory attention. PubMed: Response accuracy and odor sampling time in mice trained to discriminate between enantiomers of carvone and those of terpinen-4-ol. PubMed: Character impact odorants of fennel fruits and fennel tea. PubMed: The number of functional olfactory receptor genes and the relative size of olfactory brain structures are poor predictors of olfactory discrimination performance with enantiomers. PubMed: Composition and aroma compounds of Ragusano cheese: native pasture and total mixed rations. PubMed: Olfactory discrimination ability of human subjects for enantiomers with an isopropenyl group at the chiral center. PubMed: OMP gene deletion results in an alteration in odorant-induced mucosal activity patterns. PubMed: Olfactory discrimination of short chain fatty acids in rats with large bilateral lesions of the olfactory bulbs. PubMed: Influence of drying on the flavor quality of spearmint (Mentha spicata L.). PubMed: Sensitivity-dependent hierarchical receptor codes for odors. PubMed: Concanavalin A application to the olfactory epithelium reveals different sensory neuron populations for the odour pair D- and L-carvone. PubMed: Spontaneous versus reinforced olfactory discriminations. PubMed: A psychophysical study of the relationship between temporal processing in odor mixtures and transduction pathways. PubMed: Enantioselectivity of odor perception in honeybees (Apis mellifera carnica). PubMed: Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation. PubMed: Relationships between odor-elicited oscillations in the salamander olfactory epithelium and olfactory bulb. PubMed: Enantioselectivity of odor perception in squirrel monkeys and humans. PubMed: Olfactory discrimination ability of human subjects for ten pairs of enantiomers. PubMed: Temporal processing of odor mixtures reveals that identification of components takes precedence over temporal information in olfactory memory. PubMed: Identification of ligands for olfactory receptors by functional expression of a receptor library. PubMed: Spatially organized response zones in rat olfactory epithelium. PubMed: Ca2+ and Cl(-)-dependence of the turtle olfactory response to odorants and forskolin. PubMed: Variation in odor thresholds for l-carvone and cineole and correlations with suprathreshold intensity ratings. PubMed: Temperature increase abolishes ability of turtle olfactory receptors to discriminate similar odorant. PubMed: A mass transport model of olfaction. PubMed: Differential olfactory perception of enantiomeric compounds by blind subterranean mole rats (Spalax ehrenbergi). PubMed: Quantitative analysis on odor intensity and quality of optical isomers in turtle olfactory system. PubMed: Olfactory bulb size, odor discrimination and magnetic insensitivity in hummingbirds. PubMed: Odor masking in the rat. PubMed: Sensory evidence for olfactory receptors with opposite chiral selectivity. PubMed: Quality and intensity of binary odor mixtures. PubMed: Odor incongruity and chirality. PubMed: Odor differences between enantiomeric isomers. PubMed: Study of chemical stability of lemon oil components in sodium caseinate-lactose glycoconjugate-stabilized oil-in-water emulsions using solid-phase microextraction-gas chromatography.