myricanone

tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one, 3,15-dihydroxy-16,17-dimethoxy-

CAS: 32492-74-3 C21 H24 O5 MW: 356.41828000

Identification

Namemyricanone
CAS Number32492-74-3
FDA UNIISearch
Molecular FormulaC21 H24 O5
Molecular Weight356.41828000
Nikkaji NumberJ19.021G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 583.69 °C. @ 760.00 mm Hg (est)
Flash Point 404.00 °F. TCC ( 206.70 °C. ) (est)
logP (o/w) 3.790 (est)
Soluble in water, 1.484 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for myricanone usage levels up tonot for fragrance use.
Recommendation for myricanone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

bayberry chinese bayberry bark myrica nagi

Synonyms

3,15- dihydroxy-16,17-dimethoxytricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one 3,15- dihydroxy-16,17-dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one tricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one, 3,15-dihydroxy-16,17-dimethoxy- tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one, 3,15-dihydroxy-16,17-dimethoxy- PubMed: In vitro Anticancer Activity of Myricanone in Human Lung Adenocarcinoma A549 Cells. PubMed: Biological evaluation of secondary metabolites from the roots of Myrica adenophora. PubMed: Diarylheptanoid-myricanone isolated from ethanolic extract of Myrica cerifera shows anticancer effects on HeLa and PC3 cell lines: signalling pathway and drug-DNA interaction. PubMed: Anticancer potential of myricanone, a major bioactive component of Myrica cerifera: novel signaling cascade for accomplishing apoptosis. PubMed: Diarylheptanoid sulfates and related compounds from Myrica rubra bark. PubMed: Three new cyclic diarylheptanoids and other phenolic compounds from the bark of Myrica rubra and their melanogenesis inhibitory and radical scavenging activities. PubMed: Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene. PubMed: Chemopreventive potential of cyclic diarylheptanoids. PubMed: Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra. PubMed: Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra. PubMed: Antitumor-promoting effects of cyclic diarylheptanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis. PubMed: [Constituents of Acer nikoense and Myrica rubra. On diarylheptanoids]. PubMed: [Diarylheptanoids in the bark of Myrica rubra Sieb. et Zucc].