myricanol

tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol,16,17-dimethoxy-, (9R)-

CAS: 33606-81-4 C21 H26 O5 MW: 358.43422000

Identification

Namemyricanol
CAS Number33606-81-4
FDA UNIISearch
Molecular FormulaC21 H26 O5
Molecular Weight358.43422000
Nikkaji NumberJ19.022E

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 583.46 °C. @ 760.00 mm Hg (est)
Flash Point 584.00 °F. TCC ( 306.70 °C. ) (est)
logP (o/w) 3.677 (est)
Soluble in water, 1.708 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for myricanol usage levels up tonot for fragrance use.
Recommendation for myricanol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

anise root bayberry chinese bayberry bark

Synonyms

(R)-16,17- dimethoxytricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol (9R)-16,17- dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaene-3,9,15-triol tricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol, 16,17-dimethoxy-, (R)- tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol,16,17-dimethoxy-, (9R)- PubMed: Myricanol induces apoptotic cell death and anti-tumor activity in non-small cell lung carcinoma in vivo. PubMed: Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance. PubMed: Growth-inhibiting and apoptosis-inducing activities of Myricanol from the bark of Myrica rubra in human lung adenocarcinoma A549 cells. PubMed: Biological evaluation of secondary metabolites from the roots of Myrica adenophora. PubMed: Diarylheptanoid sulfates and related compounds from Myrica rubra bark. PubMed: The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau. PubMed: Myricarborin A and n-butyl-alpha-L-rhamnopyranoside, two novel compounds from the bark of Myrica rubra. PubMed: Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene. PubMed: Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra. PubMed: Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra. PubMed: Diarylheptanoids from Myrica arborea. PubMed: [Constituents of Acer nikoense and Myrica rubra. On diarylheptanoids]. PubMed: [Protective effects of the bark of Myrica rubra Sieb. et Zucc. on experimental liver injuries]. PubMed: [Diarylheptanoids in the bark of Myrica rubra Sieb. et Zucc].