myricanol
tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol,16,17-dimethoxy-, (9R)-
Identification
| Name | myricanol |
| CAS Number | 33606-81-4 |
| FDA UNII | Search |
| Molecular Formula | C21 H26 O5 |
| Molecular Weight | 358.43422000 |
| Nikkaji Number | J19.022E |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 583.46 °C. @ 760.00 mm Hg (est) |
| Flash Point | 584.00 °F. TCC ( 306.70 °C. ) (est) |
| logP (o/w) | 3.677 (est) |
| Soluble in | water, 1.708 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for myricanol usage levels up to | not for fragrance use. |
| Recommendation for myricanol flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Potential Uses
Natural Occurrence
Synonyms
(R)-16,17-
dimethoxytricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol
(9R)-16,17-
dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaene-3,9,15-triol
tricyclo(12.3.1.12,6)nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol, 16,17-dimethoxy-, (R)-
tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,15-triol,16,17-dimethoxy-, (9R)-
PubMed:
Myricanol induces apoptotic cell death and anti-tumor activity in non-small cell lung carcinoma in vivo.
PubMed:
Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance.
PubMed:
Growth-inhibiting and apoptosis-inducing activities of Myricanol from the bark of Myrica rubra in human lung adenocarcinoma A549 cells.
PubMed:
Biological evaluation of secondary metabolites from the roots of Myrica adenophora.
PubMed:
Diarylheptanoid sulfates and related compounds from Myrica rubra bark.
PubMed:
The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
PubMed:
Myricarborin A and n-butyl-alpha-L-rhamnopyranoside, two novel compounds from the bark of Myrica rubra.
PubMed:
Inhibitors of nitric oxide production from the bark of Myrica rubra: structures of new biphenyl type diarylheptanoid glycosides and taraxerane type triterpene.
PubMed:
Bioactive constituents of Chinese natural medicines. VII. Inhibitors of degranulation in RBL-2H3 cells and absolute stereostructures of three new diarylheptanoid glycosides from the bark of Myrica rubra.
PubMed:
Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra.
PubMed:
Diarylheptanoids from Myrica arborea.
PubMed:
[Constituents of Acer nikoense and Myrica rubra. On diarylheptanoids].
PubMed:
[Protective effects of the bark of Myrica rubra Sieb. et Zucc. on experimental liver injuries].
PubMed:
[Diarylheptanoids in the bark of Myrica rubra Sieb. et Zucc].