nerium oleander leaf extract
extract of the leaves of the rosebay, nerium oleander l., apocynaceae
Identification
| Name | nerium oleander leaf extract |
| CAS Number | 84929-39-5 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-mouse LD50 2857 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for nerium oleander leaf extract usage levels up to | not for fragrance use. |
| Recommendation for nerium oleander leaf extract flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
rose-
bay extract
extract of the leaves of the rosebay, nerium oleander l., apocynaceae
oleander extract
rosa laurel extract
rosebay leaf extract
rosebay leaves extract
PubMed:
Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer therapy?
PubMed:
Response to: Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer?
PubMed:
Clinical and pathological features of Nerium oleander extract toxicosis in wistar rats.
PubMed:
Assessment of anti-diabetic activity of an ethnopharmacological plant Nerium oleander through alloxan induced diabetes in mice.
PubMed:
PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway.
PubMed:
First-in-human study of pbi-05204, an oleander-derived inhibitor of akt, fgf-2, nf-κΠand p70s6k, in patients with advanced solid tumors.
PubMed:
In vitro antifugal activity of medicinal plant extract against Fusarium oxysporum f. sp. lycopersici race 3 the causal agent of tomato wilt.
PubMed:
Caffeoylquinic acids in leaves of selected Apocynaceae species: Their isolation and content.
PubMed:
BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin.
PubMed:
Effect of Nerium oleander (N.O.) leaves extract on serum hepcidin, total iron, and infiltration of ED1 positive cells in albino rat.
PubMed:
Prophylactic and therapeutic effects of garlic extract on Nerium oleander-induced arrhythmia: a new approach to antiarrhythmic therapy in an ovine model.
PubMed:
Exploring a natural MDR reversal agent: potential of medicinal food supplement Nerium oleander leaf distillate.
PubMed:
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells.
PubMed:
Evaluation of leaf aqueous extract and synthesized silver nanoparticles using Nerium oleander against Anopheles stephensi (Diptera: Culicidae).
PubMed:
The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: discovery of an active cardiac glycoside from Urginea maritima.
PubMed:
Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.
PubMed:
Hepatoprotective and antioxidant activity of methanolic extract of flowers of Nerium oleander against CCl4-induced liver injury in rats.
PubMed:
Antidiabetic activity evaluation of glimepiride and Nerium oleander extract on insulin, glucose levels and some liver enzymes activities in experimental diabetic rat model.
PubMed:
In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.
PubMed:
Acromyrmex octospinosus (Hymenoptera: Formicidae) management. Part 1: Effects of TRAMIL's insecticidal plant extracts.
PubMed:
Antiproliferative and phytochemical analyses of leaf extracts of ten Apocynaceae species.
PubMed:
Hypolipidemic potential of flowers of Nerium oleander in high fat diet-fed Sprague Dawley rats.
PubMed:
Acute cardiac toxicity of nerium oleander/indicum poisoning (kaner) poisoning.
PubMed:
Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum.
PubMed:
Cardioprotective effect of Nerium oleander flower against isoproterenol-induced myocardial oxidative stress in experimental rats.
PubMed:
Three new cardenolides from methanol extract of stems and twigs of Nerium oleander.
PubMed:
Response to 'Probable hepatotoxicity related to Nerium oleander extract in a patient with metastatic synovial sarcoma of the knee'.
PubMed:
Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. Schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christi L.) extracts on plants pathogenic fungi.
PubMed:
Probable hepatotoxicity related to Nerium oleander extract in a patient with metastatic synovial sarcoma of the knee.
PubMed:
Cytotoxic effects of leaf, stem and root extracts of Nerium oleander on leukemia cell lines and role of the p-glycoprotein in this effect.
PubMed:
Unexpectedly dangerous escargot stew: oleandrin poisoning through the alimentary chain.
PubMed:
Taraxasterane- and ursane-type triterpenes from Nerium oleander and their biological activities.
PubMed:
Phase 1 trial of Anvirzel in patients with refractory solid tumors.
PubMed:
A rare cause of complete heart block after transdermal botanical treatment for psoriasis.
PubMed:
Anti-inflammatory and antinociceptive activity assessment of plants used as remedy in Turkish folk medicine.
PubMed:
The cardiotonic effect of the crude ethanolic extract of Nerium oleander in the isolated guinea pig hearts.
PubMed:
Toxicity of Nerium oleander leaf extract in mice.
PubMed:
Murine pharmacokinetics and metabolism of oleandrin, a cytotoxic component of Nerium oleander.
PubMed:
Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin.
PubMed:
Anvirzel, an extract of Nerium oleander, induces cell death in human but not murine cancer cells.
PubMed:
LC/MS/MS analyses of an oleander extract for cancer treatment.
PubMed:
Oleandrin suppresses activation of nuclear transcription factor-kappaB, activator protein-1, and c-Jun NH2-terminal kinase.
PubMed:
Bio-active cardenolides from the leaves of Nerium oleander.
PubMed:
Cardenolides from the methanolic extract of Nerium oleander leaves possessing central nervous system depressant activity in mice.
PubMed:
Toxic effect of ethanolic extract of Nerium oleander (Apocynaceae) leaves against different developmental stages of Muscina stabulans (Diptera-Muscidae).
PubMed:
[Separation and identifying features of the cardiac aglycones and glycosides of Nerium oleander L. flowers by thin-layer chromatography].
PubMed:
Glycosylation of cardenolide aglycones in the leaves of Nerium oleander.
PubMed:
[Effect of several extracts derived from plants on the survival of larvae of Aedes fluviatilis (Lutz) (Diptera: Culicidae) in the laboratory].
PubMed:
Oleandrin distribution in a fatality from rectal and oral Nerium oleander extract administration.
PubMed:
[Diuretic effect of potable extract of Nerium oleander].
PubMed:
[Cardiotonic effect of potable solution of extract of the laurel rose (Nerium oleander)].