perilla ketone

1-pentanone, 1-(3-furanyl)-4-methyl-

CAS: 553-84-4 C10 H14 O2 MW: 166.21998000

Identification

Nameperilla ketone
CAS Number553-84-4
FDA UNIICV69S6Y94V
Molecular FormulaC10 H14 O2
Molecular Weight166.21998000
MDL NumberMFCD01939833
Nikkaji NumberJ69.495I
Beilstein0114624
XlogP32.80 (est)

Regulatory

Physical Properties

Appearance pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 223.00 to 225.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.091000 mmHg @ 25.00 °C. (est)
Flash Point 206.00 °F. TCC ( 96.67 °C. )
logP (o/w) 2.760
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-rat LD50 10 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for perilla ketone usage levels up tonot for fragrance use.
Recommendation for perilla ketone flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

patchouli oil china @ 0.02% Data perilla

Synonyms

1- furan-3-yl-4-methylpentan-1-one 1-( furan-3-yl)-4-methylpentan-1-one 1-(3- furanyl)-4-methyl-1-pentanone b- furyl Isoamyl Ketone beta- furyl isoamyl ketone 1-(3- furyl)-4-methyl-1-pentanone 1-(3- furyl)-4-methylpentan-1-one 1- pentanone, 1-(3-furanyl)-4-methyl- 1- pentanone, 1-(3-furyl)-4-methyl- PubMed: Inhibition of Proinflammatory Cytokine Generation in Lung Inflammation by the Leaves of Perilla frutescens and Its Constituents. PubMed: Analogues of perillaketone as highly potent agonists of TRPA1 channel. PubMed: Bovine atypical interstitial pneumonia. PubMed: Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf. PubMed: Determination of toxic perilla ketone, secondary plant metabolites and antioxidative capacity in five Perilla frutescens L. varieties. PubMed: Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens. PubMed: Perilla frutescens var. frutescens in northern Laos. PubMed: Compensated overexpression of procollagens alpha 1(I) and alpha 1(III) following perilla mint ketone-induced acute pulmonary damage in horses. PubMed: Neutral and DEAE dextrans as tracers for assessing lung microvascular barrier permeability and integrity. PubMed: Correlation between increased airway responsiveness and severity of pulmonary edema. PubMed: Effect of pulmonary edema on tracheal diameter. PubMed: Effect of cardiogenic and noncardiogenic pulmonary edema on histamine responsiveness in sheep. PubMed: Reamed intramedullary femoral nailing after induction of an "ARDS-like" state in sheep: effect on clinically applicable markers of pulmonary function. PubMed: Comparison of the pulmonary dysfunction caused by cardiogenic and noncardiogenic pulmonary edema. PubMed: Evaluation of perilla ketone-induced unilateral lung injury using external gamma scanning. PubMed: Perilla ketone increases endothelial cell monolayer permeability in vitro. PubMed: Effects of Perilla ketone on the in situ sheep lung. PubMed: The effects of selected bulky substituents on the pulmonary toxicity of 3-furyl ketones in mice. PubMed: Morphology of noncardiogenic pulmonary edema induced by Perilla ketone in sheep. PubMed: Acute bovine pulmonary emphysema caused by the fungus Fusarium semitectum. PubMed: Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep. PubMed: The Essential Oil of Perilla ocimoides: A Rich Source of Rosefuran. PubMed: Intoxication of cattle by Perilla frutescens (purple mint). PubMed: An intestinal propulsion promoting substance from Perilla frutescens and its mechanism of action. PubMed: Respiratory disease in adult cattle. PubMed: Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system. PubMed: Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease. PubMed: Chemical-induced lung injury in domestic animals. PubMed: Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton.