perilla ketone
1-pentanone, 1-(3-furanyl)-4-methyl-
Identification
| Name | perilla ketone |
| CAS Number | 553-84-4 |
| FDA UNII | CV69S6Y94V |
| Molecular Formula | C10 H14 O2 |
| Molecular Weight | 166.21998000 |
| MDL Number | MFCD01939833 |
| Nikkaji Number | J69.495I |
| Beilstein | 0114624 |
| XlogP3 | 2.80 (est) |
Regulatory
Physical Properties
| Appearance | pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 223.00 to 225.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.091000 mmHg @ 25.00 °C. (est) |
| Flash Point | 206.00 °F. TCC ( 96.67 °C. ) |
| logP (o/w) | 2.760 |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-rat LD50 10 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for perilla ketone usage levels up to | not for fragrance use. |
| Recommendation for perilla ketone flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
1-
furan-3-yl-4-methylpentan-1-one
1-(
furan-3-yl)-4-methylpentan-1-one
1-(3-
furanyl)-4-methyl-1-pentanone
b-
furyl Isoamyl Ketone
beta-
furyl isoamyl ketone
1-(3-
furyl)-4-methyl-1-pentanone
1-(3-
furyl)-4-methylpentan-1-one
1-
pentanone, 1-(3-furanyl)-4-methyl-
1-
pentanone, 1-(3-furyl)-4-methyl-
PubMed:
Inhibition of Proinflammatory Cytokine Generation in Lung Inflammation by the Leaves of Perilla frutescens and Its Constituents.
PubMed:
Analogues of perillaketone as highly potent agonists of TRPA1 channel.
PubMed:
Bovine atypical interstitial pneumonia.
PubMed:
Characteristic aroma-active compounds of Korean perilla (Perilla frutescens Britton) leaf.
PubMed:
Determination of toxic perilla ketone, secondary plant metabolites and antioxidative capacity in five Perilla frutescens L. varieties.
PubMed:
Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.
PubMed:
Perilla frutescens var. frutescens in northern Laos.
PubMed:
Compensated overexpression of procollagens alpha 1(I) and alpha 1(III) following perilla mint ketone-induced acute pulmonary damage in horses.
PubMed:
Neutral and DEAE dextrans as tracers for assessing lung microvascular barrier permeability and integrity.
PubMed:
Correlation between increased airway responsiveness and severity of pulmonary edema.
PubMed:
Effect of pulmonary edema on tracheal diameter.
PubMed:
Effect of cardiogenic and noncardiogenic pulmonary edema on histamine responsiveness in sheep.
PubMed:
Reamed intramedullary femoral nailing after induction of an "ARDS-like" state in sheep: effect on clinically applicable markers of pulmonary function.
PubMed:
Comparison of the pulmonary dysfunction caused by cardiogenic and noncardiogenic pulmonary edema.
PubMed:
Evaluation of perilla ketone-induced unilateral lung injury using external gamma scanning.
PubMed:
Perilla ketone increases endothelial cell monolayer permeability in vitro.
PubMed:
Effects of Perilla ketone on the in situ sheep lung.
PubMed:
The effects of selected bulky substituents on the pulmonary toxicity of 3-furyl ketones in mice.
PubMed:
Morphology of noncardiogenic pulmonary edema induced by Perilla ketone in sheep.
PubMed:
Acute bovine pulmonary emphysema caused by the fungus Fusarium semitectum.
PubMed:
Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep.
PubMed:
The Essential Oil of Perilla ocimoides: A Rich Source of Rosefuran.
PubMed:
Intoxication of cattle by Perilla frutescens (purple mint).
PubMed:
An intestinal propulsion promoting substance from Perilla frutescens and its mechanism of action.
PubMed:
Respiratory disease in adult cattle.
PubMed:
Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system.
PubMed:
Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease.
PubMed:
Chemical-induced lung injury in domestic animals.
PubMed:
Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton.