polygala tenuifolia root extract
extract of the roots of polygala tenuifolia, polygalaceae
Identification
| Name | polygala tenuifolia root extract |
| IUPAC | polygala tenuifolia root extract |
| CAS Number | 94167-09-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for polygala tenuifolia root extract usage levels up to | not for fragrance use. |
| Recommendation for polygala tenuifolia root extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
extract of the roots of polygala tenuifolia, polygalaceae
polygala rehmannii root extract
yuan zhi root extract
PubMed:
Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice.
PubMed:
Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.
PubMed:
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
PubMed:
Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract.
PubMed:
Neuroprotective Effects of 3,6'-Disinapoyl Sucrose Through Increased BDNF Levels and CREB Phosphorylation via the CaMKII and ERK1/2 Pathway.
PubMed:
High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells.
PubMed:
The inhibition of JNK MAPK and NF-κB signaling by tenuifoliside A isolated from Polygala tenuifolia in lipopolysaccharide-induced macrophages is associated with its anti-inflammatory effect.
PubMed:
Analysis and detection of the chemical constituents of Radix Polygalae and their metabolites in rats after oral administration by ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
PubMed:
Tenuigenin ameliorates learning and memory impairments induced by ovariectomy.
PubMed:
Tenuigenin treatment improves behavioral Y-maze learning by enhancing synaptic plasticity in mice.
PubMed:
Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats.
PubMed:
Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells.
PubMed:
Effects of the crude extract of Polygala tenuifolia Willd on human sperm in vitro.
PubMed:
Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury.
PubMed:
Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models.
PubMed:
Antioxidant activity of oligosaccharide ester extracted from Polygala tenuifolia roots in senescence-accelerated mice.
PubMed:
Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice.
PubMed:
Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms.
PubMed:
Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory.
PubMed:
Localization and dynamic change of saponin in vegetative organs of Polygala tenuifolia.
PubMed:
BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains.
PubMed:
Effects of Polygala tenuifolia root extract on proliferation of neural stem cells in the hippocampal CA1 region.
PubMed:
Effect of Polygala tenuifolia root extract on scopolamine-induced impairment of rat spatial cognition in an eight-arm radial maze task.
PubMed:
Cerebral protective and cognition-improving effects of sinapic acid in rodents.
PubMed:
Effect of Polygala tenuifolia root extract on cerebral ischemia and reperfusion.
PubMed:
[Studies on the chemical constituents in root bark of Polygala tenuifolia (II)].
PubMed:
Attenuation of cocaine-induced conditioned place preference by Polygala tenuifolia root extract.
PubMed:
Effect of Polygala tenuifolia root on behavioral disorders by lesioning nucleus basalis magnocellularis in rat.
PubMed:
Tenuifoliose Q, a new oligosaccharide ester from the root of Polygala tenuifolia Willd.
PubMed:
Induction of NGF synthesis in astrocytes by onjisaponins of Polygala tenuifolia, constituents of kampo (Japanese herbal) medicine, Ninjin-yoei-to.
PubMed:
[Studies on chemical constituents of fat oil of Polygala tenuifolia].
PubMed:
Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.
PubMed:
Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria-pertussis-tetanus vaccines.
PubMed:
Effect of Polygala tenuifolia root extract on the tumor necrosis factor-alpha secretion from mouse astrocytes.
PubMed:
[SUGAR COMPONENTS OF THE ROOT OF POLYGALA TENUIFOLIA].