prunella vulgaris extract
extract of the whole plant, self heal, prunella vulgaris l., labiatae
Identification
| Name | prunella vulgaris extract |
| IUPAC | prunella vulgaris l. extract |
| CAS Number | 90105-92-3 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 750 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION']
Safety in Use
| Category | antioxidants |
| Recommendation for prunella vulgaris extract usage levels up to | not for fragrance use. |
| Recommendation for prunella vulgaris extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
austakhadus extract
extract of the whole plant, self heal, prunella vulgaris l., labiatae
heal all extract
heal-all extract
self heal extract
self-heal extract
PubMed:
Extracts of endophytic fungus xkc-s03 from Prunella vulgaris L. spica inhibit gastric cancer in vitro and in vivo.
PubMed:
Pentacyclic triterpenoids from spikes of Prunella vulgaris L. inhibit glycogen phosphorylase and improve insulin sensitivity in 3T3-L1 adipocytes.
PubMed:
SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes.
PubMed:
Anti-diabetic effects of the ethanol extract of a functional formula diet in mice fed with a fructose/fat-rich combination diet.
PubMed:
In vitro antioxidant and anticancer effects of solvent fractions from Prunella vulgaris var. lilacina.
PubMed:
Effects of Prunella vulgaris on the mice immune function.
PubMed:
NF-κB-targeted anti-inflammatory activity of Prunella vulgaris var. lilacina in macrophages RAW 264.7.
PubMed:
Anti-Proliferative Effect of an Aqueous Extract of Prunella vulgaris in Vascular Smooth Muscle Cells.
PubMed:
The protective effect of Prunella vulgaris ethanol extract against vascular inflammation in TNF-α-stimulated human aortic smooth muscle cells.
PubMed:
Prunella vulgaris attenuates prepulse inhibition deficit and attention disruption induced by MK-801 in mice.
PubMed:
The inhibitory effect of Prunella vulgaris L. on aldose reductase and protein glycation.
PubMed:
Prunella vulgaris aqueous extract attenuates IL-1β-induced apoptosis and NF-κB activation in INS-1 cells.
PubMed:
Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes.
PubMed:
[Experimental study of extract from Prunella vulgaris inducing B, T lymphoma cell apoptosis].
PubMed:
The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases.
PubMed:
A new unusual delta11(12)-oleane triterpene and anti-complementary triterpenes from Prunella vulgaris spikes.
PubMed:
[Analyze on the component of rosmarinic acid in Prunella vulgaris and its effect on alpha-glycosidase activity].
PubMed:
Prunella vulgaris suppresses HG-induced vascular inflammation via Nrf2/HO-1/eNOS activation.
PubMed:
Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
PubMed:
Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers.
PubMed:
[Dynamic change of active component content in different parts of Prunella vulgaris].
PubMed:
Evaluation of the anti-neuraminidase activity of the traditional Chinese medicines and determination of the anti-influenza A virus effects of the neuraminidase inhibitory TCMs in vitro and in vivo.
PubMed:
Oleanolic acid from Prunella Vulgaris L. induces SPC-A-1 cell line apoptosis via regulation of Bax, Bad and Bcl-2 expression.
PubMed:
Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L.
PubMed:
Chemoprevention by Prunella vulgaris L. extract of non-small cell lung cancer via promoting apoptosis and regulating the cell cycle.
PubMed:
Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice.
PubMed:
Effect of polyacetylenic acids from Prunella vulgaris on various plant pathogens.
PubMed:
Identification of two polysaccharides from Prunella vulgaris L. and evaluation on their anti-lung adenocarcinoma activity.
PubMed:
Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.
PubMed:
The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice.
PubMed:
Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappaB-dependent MMP-9 expression.
PubMed:
Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages.
PubMed:
Prunella vulgaris extract and rosmarinic acid prevent UVB-induced DNA damage and oxidative stress in HaCaT keratinocytes.
PubMed:
Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts.
PubMed:
Inhibition of lentivirus replication by aqueous extracts of Prunella vulgaris.
PubMed:
Triterpenoic acids of Prunella vulgaris var. lilacina and their cytotoxic activities in vitro.
PubMed:
Immunostimulatory activity of aqueous extract isolated from Prunella vulgaris.
PubMed:
Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models.
PubMed:
Heme oxygenase-1 inducing constituent of Prunella vulgaris in HepG2 cells.
PubMed:
Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production.
PubMed:
Antihyperglycemic activity of Prunella vulgaris L. in streptozotocin-induced diabetic mice.
PubMed:
Photoprotective properties of Prunella vulgaris and rosmarinic acid on human keratinocytes.
PubMed:
Clematis mandshurica protected to apoptosis of rat chondrocytes.
PubMed:
In vitro and in vivo immunosuppressive activity of Spica Prunellae ethanol extract on the immune responses in mice.
PubMed:
Biological activities of Prunella vulgaris extract.
PubMed:
Inhibitory effects of rosmarinic acid on Lck SH2 domain binding to a synthetic phosphopeptide.
PubMed:
Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study.
PubMed:
Inhibition of immediate-type allergic reactions by Prunella vulgaris in a murine model.
PubMed:
A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs.
PubMed:
Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris.
PubMed:
Extract of Prunella vulgaris spikes inhibits HIV replication at reverse transcription in vitro and can be absorbed from intestine in vivo.
PubMed:
Anti-HIV-1 activity of herbs in Labiatae.
PubMed:
[Screening test of crude drug extract on anti-HIV activity].
PubMed:
Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris.