saussurea lappa root extract
extract of the roots of the costus, saussurea lappa, asteraceae
Identification
| Name | saussurea lappa root extract |
| CAS Number | 90106-55-1 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| IFRA Critical Effect | Dermal sensitization |
| Recommendation for saussurea lappa root extract usage levels up to | PROHIBITED: Should not be used as a fragrance ingredient. |
| Recommendation for saussurea lappa root extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
aucklandia costus root extract
costus root extract
extract of the roots of the costus, saussurea lappa, asteraceae
saussurea costus root extract
PubMed:
UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa.
PubMed:
Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India.
PubMed:
Evaluation of anti-resistant activity of Auklandia (Saussurea lappa) root against some human pathogens.
PubMed:
Aqueous extract of Saussurea lappa root ameliorate oxidative myocardial injury induced by isoproterenol in rats.
PubMed:
Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells.
PubMed:
Larvicidal activity of medicinal plant extracts and lignan identified in Phryma leptostachya var. asiatica roots against housefly (Musca domestica L.).
PubMed:
Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke.
PubMed:
Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells.
PubMed:
A new sesquiterpene and other constituents from Saussurea lappa root.
PubMed:
Antihepatotoxic activity of Saussurea lappa extract on D-galactosamine and lipopolysaccharide-induced hepatitis in mice.
PubMed:
Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa.
PubMed:
Authentication of Saussurea lappa, an endangered medicinal material, by ITS DNA and 5S rRNA sequencing.
PubMed:
Effects of Saussurea lappa roots extract in ethanol on leukocyte phagocytic activity, lymphocyte proliferation and interferon-gamma (IFN-gamma).
PubMed:
Presence of cholinergic and calcium antagonist constituents in Saussurea lappa explains its use in constipation and spasm.
PubMed:
Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells.
PubMed:
Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells.
PubMed:
Cytotoxic sesquiterpene lactones from the root of Saussurea lappa.
PubMed:
Germacrenes from fresh costus roots.
PubMed:
Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release.
PubMed:
Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line.
PubMed:
Effect of dehydrocostus lactone and costunolide from Saussurea root on the central nervous system in mice.
PubMed:
Effect of polyols on heat inactivation of Aspergillus niger van Teighem inulinase.
PubMed:
Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
PubMed:
Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix.
PubMed:
Sesquiterpenoids from costum root oil (Saussurea lappa Clarke)