dillapiol (dill)

1-allyl-2,3-dimethoxy-4,5-(methylenedioxy)benzene

CAS: 484-31-1 C12 H14 O4 MW: 222.24038000 woody

Identification

Namedillapiol (dill)
CAS Number484-31-1
FDA UNII438CJQ562D
Molecular FormulaC12 H14 O4
Molecular Weight222.24038000
Nikkaji NumberJ12.531H
Beilstein0196037

Regulatory

Physical Properties

Appearance colorless viscous liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.16440 @ 0.00 °C.
Refractive Index 1.53050 @ 0.00 °C.
Melting Point 28.00 to 29.00 °C. @ 760.00 mm Hg
Boiling Point 285.00 to 292.00 °C. @ 760.00 mm Hg, 160.00 to 161.00 °C. @ 10.00 mm Hg
Vapor Pressure 0.006000 mmHg @ 25.00 °C. (est)
Flash Point 222.00 °F. TCC ( 105.70 °C. ) (est)
logP (o/w) 2.343 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description wood spice

Safety Information

Oral/Parenteral Toxicityoral-mouse LD50 1000 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for dillapiol (dill) usage levels up tonot for fragrance use.
Recommendation for dillapiol (dill) flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

coriander seed oil coriander seed oil cuba @ 0.45% Data crithmum maritimum oil @ <0.10% Data cubeb oil @ 0.16% Data cumin seed dill dill leaf dill leaf oil dill oil dill plant dill root oil dill seed dill shoot oil dill weed oil cuba @ 0.31% Data fennel root oil fennel sprout parsley fruit oil parsley seed oil pepper spiked pepper perilla piper marginatum salvia leucantha trachyspermum roxburghianum benth. ex. kurz. seed oil india @ 0.20% Data

Synonyms

1- allyl-2,3-dimethoxy-4,5-(methylene dioxy) benzene 1- allyl-2,3-dimethoxy-4,5-(methylenedioxy)benzene 6- allyl-4,5-dimethoxy-1,3-benzodioxol apiole (dill) benzene, 1-allyl-2,3-dimethoxy-4,5-(methylenedioxy)- 1,3- benzodioxole, 4,5-dimethoxy-6-(2-propen-1-yl)- 1,3- benzodioxole, 4,5-dimethoxy-6-(2-propenyl)- dill apiole (dill) 4,5- dimethoxy-6-(prop-2-en-1-yl)-1,3-benzodioxole 4,5- dimethoxy-6-prop-2-enyl-1,3-benzodioxole 4,5- dimethoxy-6-prop-2-enyl-2H-benzo[d]1,3-dioxolene 1,2- methylene dioxy-5,6-dimethoxy-4-allyl benzene 1,2- methylenedioxy-5,6-dimethoxy-4-allylbenzene PubMed: [Chemical constituents of Osmanthus fragrans fruits]. PubMed: Dillapiol: a pyrethrum synergist for control of the Colorado potato beetle. PubMed: Genetic toxicity of dillapiol and spinosad larvicides in somatic cells of Drosophila melanogaster. PubMed: Chemical composition and antifungal activity of essential oils and supercritical CO2 extracts of Apium nodiflorum (L.) Lag. PubMed: The volatile constituents of Salvia leucantha. PubMed: HIV-1-inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata. PubMed: Bioactivities of Piper aduncum L. and Piper obliquum Ruiz & Pavon (Piperaceae) essential oils from Eastern Ecuador. PubMed: Potential control of Aedes aegypti (Diptera: Culicidae) with Piper aduncum L. (Piperaceae) extracts demonstrated by chromosomal biomarkers and toxic effects on interphase nuclei. PubMed: A synthetic derivative of plant allylpolyalkoxybenzenes induces selective loss of motile cilia in sea urchin embryos. PubMed: Ciliogenesis, ciliary function, and selective isolation. PubMed: Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products. PubMed: Dillapiol and Apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus. PubMed: Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense. PubMed: Evaluation of the efficacy of dill apiol and pyriproxyfen in the treatment and control of Xenopsylla cheopis flea Roths (Siphonaptera: Pulicidae). PubMed: Traditionally-used antimalarials from the Meliaceae. PubMed: Antimicrobial constituents of Foeniculum vulgare. PubMed: An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. PubMed: Evaluation of anti-inflammatory-related activity of essential oils from the leaves and resin of species of Protium. PubMed: Genetic analysis of nothoapiol formation in Perilla frutescens. PubMed: Insecticidal defenses of Piperaceae from the neotropics. PubMed: Five new prenylated p-hydroxybenzoic acid derivatives with antimicrobial and molluscicidal activity from Piper aduncum leaves. PubMed: Isolation of dillapiol from a chemotype of Perilla frutescens as an active principle for prolonging hexobarbital-induced sleep.