acetoxyvalerenic acid

(E)-3-[(1R,4S,7R,7aR)-1-acetyloxy-3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl]-2-methylprop-2-enoic acid

CAS: 81397-67-3 C17 H24 O4 MW: 292.37508000

Identification

Nameacetoxyvalerenic acid
CAS Number81397-67-3
FDA UNIISearch
Molecular FormulaC17 H24 O4
Molecular Weight292.37508000

Regulatory

Physical Properties

Appearance colorless clear viscous liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 427.00 °C. @ 760.00 mm Hg (est)
Flash Point 302.00 °F. TCC ( 150.30 °C. ) (est)
logP (o/w) 4.106 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage refrigerate in tightly sealed containers.
Soluble in alcohol

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for acetoxyvalerenic acid usage levels up tonot for fragrance use.
Recommendation for acetoxyvalerenic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

valerian

Synonyms

(2E)-3-[(1R,4S,7R,7aR)-1- acetoxy-3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl]-2-methylacrylic acid 3-(1-( acetyl oxy)-2,4,5,6,7,7a-hexahydro-3,7-dimethyl-1H-inden-4-yl)-2-methyl-2-propenoic acid acetyl valerenolic acid (E)-3-[(1R,4S,7R,7aR)-1- acetyloxy-3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl]-2-methylprop-2-enoic acid (2E)-3-[(1R,4S,7R,7aR)-1-( acetyloxy)-3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl]-2-methylprop-2-enoic acid acetylvalerenolic acid 2- propenoic acid, 3-[(1R,4S,7R,7aR)-1-(acetyloxy)-2,4,5,6,7,7a-hexahydro-3,7-dimethyl-1H-inden-4-yl]-2-methyl-, (2E)- PubMed: NF-kappaB modulators from Valeriana officinalis PubMed: Transport of a GABAA receptor modulator and its derivatives from Valeriana officinalis L. s. l. across an in vitro cell culture model of the blood-brain barrier PubMed: Quality Control of Valerianae Radix by Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) Spectroscopy PubMed: Pharmacokinetics of valerenic acid after single and multiple doses of valerian in older women PubMed: Preserved pharmacological activity of hepatocytes-treated extracts of valerian and St. John's wort PubMed: Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid PubMed: In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4 PubMed: Cytotoxic potential of valerian constituents and valerian tinctures PubMed: [Inhibition of gamma-aminobutyric acid catabolism by valerenic acid derivatives]