isoborneol
1,7,7-trimethyl bicyclo(2.2.1)heptan-2-ol
Identification
| Name | isoborneol |
| CAS Number | 10385-78-1 |
| FDA UNII | Search |
| Molecular Formula | C10 H18 O |
| Molecular Weight | 154.25266000 |
| Nikkaji Number | J46.978E |
| Beilstein | 2038056 |
| XlogP3 | 2.70 (est) |
Regulatory
Physical Properties
| Appearance | white solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 212.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.040000 mmHg @ 25.00 °C. (est) |
| Flash Point | 150.00 °F. TCC ( 65.60 °C. ) (est) |
| logP (o/w) | 2.550 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
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Potential Uses
Natural Occurrence
Synonyms
bingpian
2-
hydroxybornane
2-
hydroxycamphane
1,7,7-
trimethyl bicyclo(2.2.1)heptan-2-ol
1,7,7-
trimethylbicyclo[2.2.1]heptan-6-ol
PubMed:
Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel.
PubMed:
Natural borneol, a monoterpenoid compound, potentiates selenocystine-induced apoptosis in human hepatocellular carcinoma cells by enhancement of cellular uptake and activation of ROS-mediated DNA damage.
PubMed:
Identification of 1,8-cineole, borneol, camphor, and thujone as anti-inflammatory compounds in a Salvia officinalis L. infusion using human gingival fibroblasts.
PubMed:
Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
PubMed:
Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse.
PubMed:
Velamo do campo: its volatile constituents, secretory elements, and biological activity.
PubMed:
Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol.
PubMed:
Selective extraction of oxygenated compounds from oregano with sub-critical water.
PubMed:
Contact toxicity, feeding reduction, and repellency of essential oils from three plants from the ginger family (Zingiberaceae) and their major components against Sitophilus zeamais and Tribolium castaneum.
PubMed:
Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco.
PubMed:
Investigation of sensory and volatile characteristics of farmed and wild barramundi (Lates calcarifer) using gas chromatography-olfactometry mass spectrometry and descriptive sensory analysis.
PubMed:
Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines.
PubMed:
Effects of borneol on the level of DNA damage induced in primary rat hepatocytes and testicular cells by hydrogen peroxide.
PubMed:
Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis.
PubMed:
Antioxidant property of volatile oils determined by the ferric reducing ability.
PubMed:
Fragrance material review on isoborneol.
PubMed:
Fragrance material review on l-borneol.
PubMed:
Fragrance material review on borneol.
PubMed:
The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity.
PubMed:
Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaris.
PubMed:
Bismuth subgallate/borneol (suile) is superior to bacitracin in the human forearm biopsy model for acute wound healing.
PubMed:
Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils.
PubMed:
[Measurement of borneol based on near infrared spectroscopy].
PubMed:
High-affinity monoclonal antibodies for detection of the microbial metabolite, 2-methylisoborneol.
PubMed:
Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. Var. pectinatus (Lamiaceae).
PubMed:
Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction-gas chromatography, solid-phase microextraction-gas chromatography-mass spectrometry and olfactometry.
PubMed:
Volatile compounds emitted by sclerotia of Sclerotinia minor, Sclerotinia sclerotiorum, and Sclerotium rolfsii.
PubMed:
Composition and antimicrobial activity of the essential oils of Micromeria cristata subsp. phrygia and the enantiomeric distribution of borneol.
PubMed:
Biochemical characterization of ochratoxin A-producing strains of the genus Penicillium.
PubMed:
Fungal volatiles as indicators of food and feeds spoilage.
PubMed:
Penicillium discolor, a new species from cheese, nuts and vegetables.
PubMed:
[Stereochemical structure of d-borneol in "the Japanese Standards of Food Additives"].
PubMed:
Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay.
PubMed:
Action of douglas fir tussock moth larvae and their microflora on dietary terpenes.