glaucarubin

(1beta,2alpha,11beta,12alpha,15beta(S))-11,20- epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy) picras-3-en-16-one glarubin glaucarubina glaumeba alpha- kirondrin MK-53 simarubaceae PubMed: Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases. PubMed: The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans. PubMed: Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines. PubMed: Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition. PubMed: Antiviral activity of simalikalactone D, a quassinoid from Quassia africana. PubMed: Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. PubMed: Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack. PubMed: Insect antifeedant and growth regulating activities of quassinoids from Samadera indica. PubMed: Total synthesis of (+)-quassin. PubMed: Nematocidal activity of quassinoids against a species of Diplogastridae. PubMed: Studies on the anxiolytic activity of Eurycoma longifolia Jack roots in mice. PubMed: Quassinoids from the twigs and thorns of Castela polyandra. PubMed: Anti-malarial activities of acylated bruceolide derivatives. PubMed: In vitro anti-trichomonic activity of Castela texana. PubMed: Anticancer activity of glaucarubinone analogues. PubMed: Mode of action of the anticancer quassinoids--inhibition of the plasma membrane NADH oxidase. PubMed: Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships. PubMed: Effect of the quassinoids glaucarubolone and simalikalactone D on growth of cells permanently infected with feline and human immunodeficiency viruses and on viral infections. PubMed: Anti-tuberculosis activity of quassinoids. PubMed: Synthesis of cytotoxic fluorinated quassinoids. PubMed: [Weitz' aminium salt initiated electron transfer reactions and application to the synthesis of natural products]. PubMed: Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion. PubMed: Inhibitory effects of quassinoid derivatives on Epstein-Barr virus early antigen activation. PubMed: Quassinoids as inhibitors of Epstein-Barr virus early antigen activation. PubMed: Antifertility activity of Quassia amara in male rats - in vivo study. PubMed: Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. PubMed: Two new quassinoids, ailantinols A and B, and related compounds from Ailanthus altissima. PubMed: Effect of 7-day daily replacement of culture medium containing Eurycoma longifolia Jack constituents on the Malaysian Plasmodium falciparum isolates. PubMed: Bruceanols G and H cytotoxic quassinoids from Brucea antidysenterica. PubMed: Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica. PubMed: Antifertility activity of Quassia amara: quassin inhibits the steroidogenesis in rat Leydig cells in vitro. PubMed: In vitro antimalarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates. PubMed: In vitro cytotoxicity of chaparrin from Castela texana. PubMed: Effects of chaparrin, nordihydroguaiaretic acid and their structural analogues on Entamoeba histolytica cultures. PubMed: Antimalarial activity of cedronin. PubMed: Bruceanols D, E, and F three new cytotoxic quassinoids from Brucea antidysenterica. PubMed: A new antimalarial quassinoid from Simaba guianensis. PubMed: Quassinoids exhibit greater selectivity against Plasmodium falciparum than against Entamoeba histolytica, Giardia intestinalis or Toxoplasma gondii in vitro. PubMed: Effect of quassin on the metabolism of catecholamines in different life cycle stages of Culex quinquefasciatus. PubMed: Cytotoxic quassinoids from Cedronia granatensis. PubMed: Mode of action of the antitumor compound girodazole (RP 49532A, NSC 627434). PubMed: Antitumor agents, 127. Bruceoside C, a new cytotoxic quassinoid glucoside, and related compounds from Brucea javanica. PubMed: Larvicidal efficacy of Quassin against Culex quinquefasciatus. PubMed: Picrasinoside H, a new quassinoid glucoside, and related compounds from the stem wood of Picrasma ailanthoides. PubMed: In vitro cytotoxicity of a series of quassinoids from Brucea javanica fruits against KB cells. PubMed: Antitumor agents, 118. The isolation and characterization of bruceanic acid A, its methyl ester, and the new bruceanic acids B, C, and D, from Brucea antidysenterica. PubMed: [Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea javanica (L.) Merr]. PubMed: [Studies on the chemical constituents of Brucea javanica (L.) Merr]. PubMed: Studies on the constituents of Indonesian Picrasma javanica. III. Structures of new quassinoids, javanicins A, C and D. PubMed: Antitumor agents, 104. Isolation of yadanziosides M and P from Brucea antidysenterica and identification of bruceantinoside B as a mixture of yadanzioside P and bruceantinoside C. PubMed: Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids. PubMed: 1H- and 13C-NMR spectroscopic studies of selected quassinoids. PubMed: Antitumor activity of novel ailanthone derivatives in vitro and in vivo. PubMed: Antitumor agents, 93. Bruceanol C, a new cytotoxic quassinoid from Brucea antidysenterica. PubMed: Metabolism of plant-derived anticancer agents. PubMed: Antitumor agents, 90. Bruceantinoside C, a new cytotoxic quassinoid glycoside from Brucea antidysenterica. PubMed: Antimalarial agents, 4. Synthesis of a brusatol analog and biological activity of brusatol-related compounds. PubMed: Acute insecticidal activity of quassin and its congeners against the American cockroach. PubMed: Plants as sources of antimalarial drugs, Part 4: Activity of Brucea javanica fruits against chloroquine-resistant Plasmodium falciparum in vitro and against Plasmodium berghei in vivo. PubMed: [Therapeutic trials of experimental murine malaria with the quassinoid, glaucarubinone]. PubMed: Yadanzioside P, a new antileukemic quassinoid glycoside from Brucea javanica (L.) Merr with the 3-O-(beta-D-glucopyranosyl)bruceantin structure. PubMed: Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids. PubMed: Two new quassinoids from Simaba multiflora fruits. PubMed: [Castela texana: screening for its anti-amoebic activity]. PubMed: Antitumor agents, 74. Bruceanol-A and -B, two new antileukemic quassinoids from Brucea antidysenterica. PubMed: Growth inhibitory, insecticidal and antifeedant effects of some antileukemic and cytotoxic quassinoids on two species of agricultural pests. PubMed: Quassinoid bitter principles. II. PubMed: Evaluation of bleomycin, chlorozotocin, MGBG, and bruceantin in patients with advanced soft tissue sarcoma, bone sarcoma, or mesothelioma. PubMed: Antitumor agents, 65. Brusatol and cleomiscosin-A, antileukemic principles from Brucea javanica. PubMed: Reversibility of protein synthesis inhibition by quassinoid antineoplastic agents in a rabbit reticulocyte system. PubMed: An enzyme-linked immunosorbent assay for quassin and closely related metabolites. PubMed: Anti-inflammatory agents III: Structure-activity relationships of brusatol and related quassinoids. PubMed: Antimalarial activity of bruceantin in vitro. PubMed: Antitumor agents LIX: effects of quassinoids on protein synthesis of a number of murine tumors and normal cells. PubMed: Structure-activity relationships for binding and inactivation of rabbit reticulocyte ribosomes by quassinoid antineoplastic agents. PubMed: A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma. PubMed: Phase II trial of bruceantin in metastatic breast carcinoma. PubMed: Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica. PubMed: Antitumor agents XLVIII: Structure-activity relationships of quassinoids as in vitro protein synthesis inhibitors of P-388 lymphocytic leukemia tumor cell metabolism. PubMed: Antitumor agents XLVI: In vitro effects of esters of brusatol, bisbrusatol, and related compounds on nucleic acid and protein synthesis of P-388 lymphocytic leukemia cells. PubMed: Antitumor agents XLV: Bisbrusatolyl and brusatolyl esters and related compounds as novel potent antileukemic agents. PubMed: Antitumor agents XLVII: The effects of bisbrusatolyl malonate on P-388 lymphocytic leukemia cell metabolism. PubMed: Clinical pharmacology of bruceantin by radioimmunoassay. PubMed: [Mode of action of new antitumor compounds]. PubMed: In vitro activity of certain quassinoid anti-tumor agents against Entamoeba histolytica. PubMed: Antitumor agents XLII: Comparison of antileukemic activity of helenalin, brusatol, and bruceantin and their esters on different strains of P-388 lymphocytic leukemic cells. PubMed: Phase I study on bruceantin administered on a weekly schedule. PubMed: Mechanism of eukaryotic protein synthesis inhibition by brusatol. PubMed: Antitumor agents. 39. Bruceantinoside-A and -B, novel antileukemic quassinoid glucosides from Brucea antidysenterica. PubMed: Soularubinone, a new antileukemic quassionoid from Soulamea tomentosa. PubMed: Antimalarial activity of quassinoids against chloroquine-resistant Plasmodium falciparum in vitro. PubMed: Bruceolides from Filjian Brucea javanica. PubMed: [Antiamebic properties of some derivatives of ailantone and quassin]. PubMed: [The chemical constituents of the Chinese drug "Yadanzi." I. Isolation and identification of daucosterol, brucein D and brucein E (author's transl)]. PubMed: Radioimmunoassay for the detection and quantitation of bruceantin. PubMed: The antineoplastic quassinoids of Simaba cuspidata spruce and Ailanthus grandis Prain. PubMed: Bruceantin, an inhibitor of the initiation of protein synthesis in eukaryotes [proceedings]. PubMed: Structural requirements of quassinoids for the inhibition of cell transformation. PubMed: Cytotoxic bruceolides from Brucea javanica [proceedings]. PubMed: Phase I trial of bruceantin. PubMed: Initial clinical studies with bruceantin. PubMed: Antitumor agents. XXXIV: Mechanism of action of bruceoside A and brusatol on nucleic acid metabolism of P-388 lymphocytic leukemia cells. PubMed: Antitumor agents. XXXV: Effects of brusatol, bruceoside A, and bruceantin on P-388 lymphocytic leukemia cell respiration. PubMed: Disposition and metabolism of bruceantin in the mouse. PubMed: Potential anticancer agents IX. Isolation of a new simaroubolide, 6alpha-tigloyloxychaparrinone, from Ailanthus integrifolia ssp. calycina (Simaroubaceae). PubMed: Plant antitumor agents. XVI. 6alpha-Senecioyloxy-chaparrinone, a new antileukemic quassinoid from Simaba multiflora. PubMed: New natural products of interest under development at the National Cancer Institute. PubMed: Potential anticancer agents vi. Constituents of Ailanthus excelsa (Simaroubaceae). PubMed: Antitumor plants. IV. Constituents of Simarouba versicolor. PubMed: Structural requirements for biological activity among antileukemic glaucarubolone ester quassinoids. PubMed: Treatment of amebic abscess of the liver. PubMed: Effects of amebicides on growth of Acanthamoeba sp. PubMed: CRYSTAL AND MOLECULAR STRUCTURE OF GLAUCARUBIN. PubMed: [The treatment of intestinal amebiasis with glaucarubin. Apropos of 173 case]. PubMed: [Treatment of autochthonous chronic non-dy-senteric amebiasis with glaucarubin]. PubMed: [The treatment of intestinal amebiasis by glaucarubin]. PubMed: Chemotherapeutic and pharmacological studies on glaucarubin, a specific amebacide. PubMed: The use of glaucarubin (a crystalline glycoside isolated from Simarouba glauca) in the treatment of human colonic amebiasis. PubMed: Symposium on the treatment of human amoebiasis. II. The treatment of intestinal amoebiasis with emetine bismuth iodide, glaucarubin, dichloroacet-hydroxy-methylanilide, camoform and various antibiotics. PubMed: Clinical trial of glaucarubin in treatment of amebiasis.