Identification

Namethymol
IUPAC5-methyl-2-propan-2-ylphenol
CAS Number89-83-8
EINECS201-944-8
FDA UNII3J50XA376E
Molecular FormulaC10 H14 O
Molecular Weight150.22078000
MDL NumberMFCD00002309
Nikkaji NumberJ10.606B
Beilstein1907135
CoE Number174
XlogP33.30 (est)

Regulatory

JECFA Food Flavoring709 thymol
DG SANTE Food Flavourings04.006 thymol
FEMA Number3066
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)89-83-8 ; THYMOL
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance white crystalline solid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed Yes
Melting Point 49.00 to 51.00 °C. @ 760.00 mm Hg
Boiling Point 231.00 to 232.00 °C. @ 760.00 mm Hg, 143.00 to 144.00 °C. @ 50.00 mm Hg
Congealing Point 49.30 °C.
Vapor Pressure 0.038000 mmHg @ 25.00 °C.
Flash Point 216.00 °F. TCC ( 102.22 °C. )
logP (o/w) 3.300
Shelf Life 36.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water
Stability non-discoloring in most media

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesdenaturants

Organoleptic Properties

Odor Strength high ,
Substantivity 176 hour(s) at 20.00 % in dipropylene glycol
Odor Description
at 1.00 % in dipropylene glycol.
Spicy, phenolic and thymol with a chemical, medicinal, camphoreous nuance
warm, thyme-like, medicinal
phenolic, camphoraceous, thyme
Odor sample from Sigma-Aldrich
Taste Description
Phenolic, medicinal, woody and spicy
strong spicy, thyme-like, phenolic, herbal
aromatic, medicinal

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 980 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 243 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE\nLUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION']

Safety in Use

Categoryflavor and fragrance agents
Recommendation for thymol usage levels up to0.1000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)51.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)160.00 (μg/capita/day)
Structure ClassI
baked goods5.00000
beverages(nonalcoholic)2.50000
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-504-6093 account@bocsci.com

ECSA Chemicals

International trading and distribution

ECSA Group offers its customers in these business segments a complete 'one-stop shopping' solution.

View All Website +41 91 695 88 00 marketing@ecsa.ch

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

View All Website +86 (0)592 5105533 info@foreverest.cn

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Global Essence Inc.

Preferred Partner

Accommodate each customers unique needs.

View All Website 001 732 677 1100 info@globalessenceuk.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

PerfumersWorld Ltd.

feeeel... the smell!

The one-stop resource for the creative perfumer.

View All Website +66(0)2-99-800-80 pwenquiries@perfumersworld.com

Prodasynth

PRODUCTEUR PAR ESSENCE

Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.

View All Website (33) 4 93 09 00 11 info@prodasynth.com

Robertet, Inc.

HOME OF NATURE, SEED TO SCENT

HOME OF NATURE – natural ingredients from the source.

View All Website +1.201.337.7100 info@robertetUSA.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

Symrise AG

Always Insiring More

Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.

View All Website +49 5531 90 0 scentandcare@symrise.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The Good Scents Company

Fragrance Creators

For your fragrance creations.

View All Website 414-764-2659 goodscnt@thegoodscentscompany.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Continued Customer Satisfaction

We employ our five senses to do our job well.

View All Website +34 934706210 info@ventos.com

Vigon International, Inc.

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

Potential Uses

FL/FR ajowan FR alpine bouquet FR bouquet FR florida soap FR herbal FR mint FR oregano FR peppermint FR pizza FR spice FR thyme oil white replacer FR windsor soap FR wintergreen FR yew

Natural Occurrence

ajowan seed oil turkey @ 61.31% Data anise oil armoise oil morocco @ trace% Data artemisia variabilis flower oil italy @ 0.80% Data basil leaf basil oil basil shoot oil bay laurel leaf oil bergamot plant wild blackberry fruit PMC blueberry fruit boldo leaf oil italy @ 0.07% Data boldus leaf oil chile @ 0.03% Data carrot seed oil spain @ trace-0.35% Data cascarilla bark oil @ trace% Data celery seed celery seed oil chenopodium ambrosioides oil @ 2.0% Data cistus oil @ 0.2% Data clary sage oil greece @ trace% Data coriander seed oil corn seed oil corn silk crithmum maritimum l. oil turkey @ <0.10% Data croton cajucara benth. leaf oil brazil @ 0.10% Data croton flavens l. (welensali) leaf oil curacao @ trace% Data cumin seed oil dill herb dill shoot oil dill weed oil cuba @ 0.16% Data dill weed oil reunion @ trace% Data eucalyptus camaldulensis dehn. leaf oil jerusalem @ 0.40% Data eucalyptus delegatensis r. baker leaf oil ethiopia @ 0.40% Data eucalyptus globulus bud oil @ 0.14% Data eucalyptus globulus fruit oil @ 0.28% Data eucalyptus globulus oil rwanda @ trace% Data featherfew leaf oil @ trace% Data fir needle oil canada @ 0.00-2.89% Data geranium rose-scented oil (pelargonium spp.) cuba @ 0.10% Data ginkgo biloba wood grapefruit guava leaf oil cuba @ 0.10% Data helichrysum arenarium (l.) moench oil hungary @ 0.60% Data horsemint shoot hyssop shoot laurel leaf oil turkey @ trace% Data lavender oil france @ trace% Data lemon balm shoot lemon leaf oil lemon pericarp oil lemon verbena oil morocco @ 0.3% Data licorice lime oil expressed florida @ trace% Data lippia aff. gracillis h.b.k. leaf oil brazil @ 8.00% Data mandarin fruit mandarin oil @ trace% Data mandarin oil avana @ 0.02% Data mandarin oil avana @ 0.11% Data mandarin oil italy @ 0.05% Data mandarin oil italy @ trace% Data mangrove bark red oil cuba @ 0.70% Data marjoram oil marjoram oil @ 0.51% Data marjoram oil spain @ trace% Data marjoram oil sweet cuba @ 11.55% Data marjoram oil sweet cyprus @ 0.00-0.10% Data marjoram oil sweet morocco @ 0.56% Data marjoram oil sweet turkey @ 0.48-1.53% Data marjoram pot oil turkey @ 0.17-39.81% Data marjoram shoot oil mikan peel oil @ trace% Data nepeta betonicifolia c.a. meyer oil turkey @ 1.20% Data orange fruit orange peel oil bitter china @ 0.12% Data oregano flower oil oregano leaf oregano oil oregano oil mexico @ 46.30% Data oregano plant oregano plant oregano shoot oregano shoot oregano shoot oil origanum oil greece @ 0.25% Data osmanthus absolute @ 0.23% Data parsley leaf parsley leaf oil cuba @ 0.02% Data pennyroyal oil cuba @ 3.03% Data peppermint oil petitgrain lemon oil peucedanum petiolare (dc) boiss oil iran @ 0.10% Data pimenta leaf oil @ 1.00% Data plectranthus glandulosus hook f. leaf oil cameroon @ 0.40% Data prangos uechtritzii boiss. et hausskn. fruit oil turkey @ 3.50% Data rosemary oil CO2 extract @ 0.69% Data rosemary oil france @ 0.00-0.18% Data rosemary oil turkey @ 0.90% Data rosemary plant rosemary shoot oil sage leaf sage oil sage oil dalmatian @ 0.20% Data sage oil england @ 0.20% Data salvia atropatana bunge oil iran @ 0.40% Data salvia officinalis seed oil tunisia @ 0.37% Data salvia sclarea seed oil tunisia @ 0.10% Data satureja khuzistanica jamzad oil iran @ trace% Data savory oil summer @ 0.12-0.14% Data savory oil winter @ 0.30% Data savory oleoresin winter @ 0.30% Data savory summer savory plant savory winter savory oil savory winter savory plant spearmint oil tanacetum annum l. oil marocco @ 0.80% Data tansy oil marocco @ 1.20% Data tea leaf thyme thyme absolute @ 43.10% Data thyme oil thyme oil portuguese @ 0.2% Data thyme oil red CO2 extract @ 36.59% Data thyme oil red CO2 extract spain @ 13.2% Data thyme oil red india @ 60.1% Data thyme oil red spain @ 16.55-38.24% Data thyme oil spain @ 34.18% Data thyme oil spain @ 71.84% Data thyme oil wild or creeping canada @ 3.50% Data thyme oil wild or creeping pakistan @ 42.63% Data thyme plant thyme shoot thymus richardii pers. subsp. nitidus (guss.) jalas oil italy @ 1.30% Data valerian root oil @ 0.1% Data walnut black walnut oil wormseed oil america @ 0.02% Data wormseed oil spain @ 1.0% Data wormwood oil annus france @ 0.00-0.83% Data yarrow oil greece @ 0.10% Data yuzu peel oil c.p. @ 0.12-0.21% Data yuzu peel oil CO2 extract @ 0.24-1.10% Data

Synonyms

apiguard p- cymen-3-ol para- cymen-3-ol 3-p- cymenol 3-para- cymenol a- cymophenol alpha- cymophenol 3- hydroxy p-cymene 2- hydroxy-1-isopropyl-4-methylbenzene 3- hydroxy-1-methyl-4-isopropylbenzene 1- hydroxy-5-methyl-2-isopropylbenzene 3- hydroxy-p-cymene 3- hydroxy-para-cymene 5- methyl-2-(1-methyl ethyl) phenol 5- methyl-2-(1-methylethyl)-phenol 5- methyl-2-(1-methylethyl)phenol 5- methyl-2-(methylethyl)phenol 5- methyl-2-(propan-2-yl)phenol 5- methyl-2-isopropyl-1-phenol 5- methyl-2-isopropylphenol 5- methyl-2-propan-2-ylphenol 5- methyl-2,1-methyl ethyl phenol 1- methyl-3-hydroxy-4- isopropylbenzene 1- methyl-3-hydroxy-4-isopropylbenzene 3- methyl-6-isopropylphenol phenol, 5-methyl-2-(1-methylethyl)- iso propyl cresol 6-iso propyl-3-methyl phenol 6-iso propyl-3-methylphenol 2-iso propyl-5-methyl phenol 2-iso propyl-5-methyl-phenol 2-iso propyl-5-methylphenol 6-iso propyl-m-cresol 6-iso propyl-meta-cresol 6-iso propyl-p-cresol 6-iso propyl-para-cresol thyme camphor thymic acid thymol cryst. thymol crystal natural thymol crystals thymol crystals (natural) thymol crystals N.F. thymol crystals natural thymol crystals NF thymol crystals U.S.P. thymol dist. thymol extra thymol natural thymol NF fine powder 60 mesh thymol USP natural PubMed: The role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies. PubMed: Satureja horvatii essential oil: in vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. PubMed: Encapsulation altered starch digestion: toward developing starch-based delivery systems. PubMed: A comparative study of the antioxidant/prooxidant effects of carvacrol and thymol at various concentrations on membrane and DNA of parental and drug resistant H1299 cells. PubMed: Volatiles profiling in medicinal licorice roots using steam distillation and solid-phase microextraction (SPME) coupled to chemometrics. PubMed: Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats. PubMed: Evaluation of natural antimicrobials on typical meat spoilage bacteria in vitro and in vacuum-packed pork meat. PubMed: Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis. PubMed: Study on the synergic effect of natural compounds on the microbial quality decay of packed fish hamburger. PubMed: Chemical composition of volatile extract and biological activities of volatile and less-volatile extracts of juniper berry (Juniperus drupacea L.) fruit. PubMed: Improvement of the overall quality of table grapes stored under modified atmosphere packaging in combination with natural antimicrobial compounds. PubMed: Anticariogenic activity of macelignan isolated from Myristica fragrans (nutmeg) against Streptococcus mutans. PubMed: Preservative effect of combined treatment with electrolyzed NaCl solutions and essential oil compounds on carp fillets during convectional air-drying. PubMed: Toxicological properties of thio- and alkylphenols causing flavor tainting in fish from the upper Wisconsin River. PubMed: A method for quantitative analysis of flavor-tainting alkylphenols and aromatic thiols in fish.