neurosporene
psi,psi-carotene, 7,8-dihydro-
Identification
| Name | neurosporene |
| IUPAC | (6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26,30-dodecaene |
| CAS Number | 502-64-7 |
| FDA UNII | Search |
| Molecular Formula | C40 H58 |
| Molecular Weight | 538.90226000 |
| Nikkaji Number | J367.196H |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 6.593e-014 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for neurosporene usage levels up to | not for fragrance use. |
| Recommendation for neurosporene flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
psi,psi-
carotene, 7,8-dihydro-
7,8-
dihydro-psi,psi-carotene
(6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2,6,10,14,19,23,27,31-
octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26,30-dodecaene
PubMed:
Effect of Illumination Intensity and Inhibition of Carotenoid Biosynthesis on Assembly of Peripheral Light-Gathering Complexes in Purple Sulfur Bacteria C Allochromatium vinosum ATCC 17899.
PubMed:
High carotenoid production by a halotolerant bacterium, Kocuria sp. strain QWT-12 and anticancer activity of its carotenoid.
PubMed:
Origin of the S* Excited State Feature of Carotenoids in Light-Harvesting Complex 1 from Purple Photosynthetic Bacteria.
PubMed:
Functional Lycopene Cyclase (CruA) in Cyanobacterium, Arthrospira platensis NIES-39, and its Role in Carotenoid Synthesis.
PubMed:
A metabolomic evaluation of the phytochemical composition of tomato juices being used in human clinical trials.
PubMed:
Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.
PubMed:
Thermal processing differentially affects lycopene and other carotenoids in cis-lycopene containing, tangerine tomatoes.
PubMed:
Vibronic coupling in the excited-states of carotenoids.
PubMed:
Identification and spectroscopic characterization of neurosporene.
PubMed:
Enhanced bioavailability of lycopene when consumed as cis-isomers from tangerine compared to red tomato juice, a randomized, cross-over clinical trial.
PubMed:
Assembly of functional photosystem complexes in Rhodobacter sphaeroides incorporating carotenoids from the spirilloxanthin pathway.
PubMed:
Distribution of colored carotenoids between light-harvesting complexes in the process of recovering carotenoid biosynthesis in Ectothiorhodospira haloalkaliphila cells.
PubMed:
Multiple transformation with the crtYB gene of the limiting enzyme increased carotenoid synthesis and generated novel derivatives in Xanthophyllomyces dendrorhous.
PubMed:
Construction of carotenoid biosynthetic pathways using squalene synthase.
PubMed:
Dissection of tomato lycopene biosynthesis through virus-induced gene silencing.
PubMed:
Acyclic carotenoid and cyclic apocarotenoid cleavage by an orthologue of lignostilbene-α,β-dioxygenase in Rhodopseudomonas palustris.
PubMed:
Neurosporene is the major carotenoid accumulated by Rhodobacter viridis JA737.
PubMed:
New insight into the cleavage reaction of Nostoc sp. strain PCC 7120 carotenoid cleavage dioxygenase in natural and nonnatural carotenoids.
PubMed:
Heterologous carotenoid-biosynthetic enzymes: functional complementation and effects on carotenoid profiles in Escherichia coli.
PubMed:
High-level production of the industrial product lycopene by the photosynthetic bacterium Rhodospirillum rubrum.
PubMed:
Carotenogenesis gene cluster and phytoene desaturase catalyzing both three- and four-step desaturations from Rhodobacter azotoformans.
PubMed:
Rhodobacter viridis sp. nov., a phototrophic bacterium isolated from mud of a stream.
PubMed:
Elucidation of the biosynthetic pathway for Okenone in Thiodictyon sp. CAD16 leads to the discovery of two novel carotene ketolases.
PubMed:
Carotenoid radical formation: dependence on conjugation length.
PubMed:
Structural and kinetics properties of a mutated phytoene desaturase from Rubrivivax gelatinosus with modified product specificity.
PubMed:
Ultrafast time-resolved absorption spectroscopy of geometric isomers of carotenoids.
PubMed:
Ultrafast Time-resolved Absorption Spectroscopy of Geometric Isomers of Carotenoids.
PubMed:
Excitation energy transfer and carotenoid radical cation formation in light harvesting complexes - a theoretical perspective.
PubMed:
Carotenoids and carotenogenic genes in Podospora anserina: engineering of the carotenoid composition extends the life span of the mycelium.
PubMed:
Heterogeneity of carotenoid content and composition in LH2 of the purple sulphur bacterium Allochromatium minutissimum grown under carotenoid-biosynthesis inhibition.
PubMed:
Isorenieratene biosynthesis in green sulfur bacteria requires the cooperative actions of two carotenoid cyclases.
PubMed:
Ultrafast time-resolved carotenoid to-bacteriochlorophyll energy transfer in LH2 complexes from photosynthetic bacteria.
PubMed:
Mutation of a single residue, beta-glutamate-20, alters protein-lipid interactions of light harvesting complex II.
PubMed:
Culture characteristics of carotenoid-producing filamentous fungus T-1, and carotenoid production.
PubMed:
Evaluation of colors in green mutants isolated from purple bacteria as a host for colorimetric whole-cell biosensors.
PubMed:
Role of B800 in carotenoid-bacteriochlorophyll energy and electron transfer in LH2 complexes from the purple bacterium Rhodobacter sphaeroides.
PubMed:
Ultrafast dynamics and excited state spectra of open-chain carotenoids at room and low temperatures.
PubMed:
Kinetic variations determine the product pattern of phytoene desaturase from Rubrivivax gelatinosus.
PubMed:
Carotenoid radical cation formation in LH2 of purple bacteria: a quantum chemical study.
PubMed:
Astaxanthin formation in the marine photosynthetic bacterium Rhodovulum sulfidophilum expressing crtI, crtY, crtW and crtZ.
PubMed:
Mechanism of carotenoid singlet excited state energy transfer in modified bacterial reaction centers.
PubMed:
Sll0254 (CrtL(diox)) is a bifunctional lycopene cyclase/dioxygenase in cyanobacteria producing myxoxanthophyll.
PubMed:
Investigation of the effects of different carotenoids on the absorption and CD signals of light harvesting 1 complexes.
PubMed:
Monocyclic carotenoid biosynthetic pathway in the yeast Phaffia rhodozyma (Xanthophyllomyces dendrorhous).
PubMed:
Efficient light harvesting through carotenoids.
PubMed:
Accumulation of unusual carotenoids in the spheroidene pathway, demethylspheroidene and demethylspheroidenone, in an alkaliphilic purple nonsulfur bacterium Rhodobaca bogoriensis.
PubMed:
Effects of carotenoid inhibition on the photosynthetic RC-LH1 complex in purple sulphur bacterium Thiorhodospira sibirica.
PubMed:
Construction and characterization of genetically modified synechocystis sp. PCC 6803 photosystem II core complexes containing carotenoids with shorter pi-conjugation than beta-carotene.
PubMed:
[Isoprenoid pigments in representatives of the family Microbacteriaceae].
PubMed:
Photo-oxidative stress in Rhodobacter sphaeroides: protective role of carotenoids and expression of selected genes.
PubMed:
Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde.
PubMed:
Analysis in vitro of the enzyme CRTISO establishes a poly-cis-carotenoid biosynthesis pathway in plants.
PubMed:
Elimination of polarity in the carotenoid terminus promotes the exposure of B850-binding sites (Tyr 44, 45) and ANS-mediated energy transfer in LH2 complexes of Rhodobacter sphaeroides.
PubMed:
Conjugation length dependence of internal conversion in carotenoids: role of the intermediate state.
PubMed:
zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene.
PubMed:
Acquirement and characterization of a carotenoid mutant (GM309) of Rhodobacter sphaeroides 601.
PubMed:
Slr1293 in Synechocystis sp. strain PCC 6803 Is the C-3',4' desaturase (CrtD) involved in myxoxanthophyll biosynthesis.
PubMed:
Asymmetrically acting lycopene beta-cyclases (CrtLm) from non-photosynthetic bacteria.
PubMed:
Role of the C-terminal extrinsic region of the alpha polypeptide of the light-harvesting 2 complex of Rhodobacter sphaeroides: a domain swap study.
PubMed:
Response of Escherichia coli Containing Mycobacterial Carotene Genes to UV Radiation.
PubMed:
Chemistry, distribution, and metabolism of tomato carotenoids and their impact on human health.
PubMed:
Carotenoid composition and vitamin A value of an Argentinian squash (Cucurbita moschata).
PubMed:
Functional assembly of the foreign carotenoid lycopene into the photosynthetic apparatus of Rhodobacter sphaeroides, achieved by replacement of the native 3-step phytoene desaturase with its 4-step counterpart from Erwinia herbicola.
PubMed:
Tangerine dreams: cloning of carotenoid isomerase from Arabidopsis and tomato.
PubMed:
Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase.
PubMed:
Phytoene desaturase, CrtI, of the purple photosynthetic bacterium, Rubrivivax gelatinosus, produces both neurosporene and lycopene.
PubMed:
Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution.
PubMed:
Biosynthesis of carotenoids in plastids of plants.
PubMed:
A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa.
PubMed:
Carotenoid and ultrastructure variations in plastids of Arum italicum Miller fruit during maturation and ripening.
PubMed:
Substrate specificity of the expressed carotenoid 3,4-desaturase from Rubrivivax gelatinosus reveals the detailed reaction sequence to spheroidene and spirilloxanthin.
PubMed:
Catalytic properties of an expressed and purified higher plant type zeta-carotene desaturase from Capsicum annuum.
PubMed:
Heliorestis daurensis, gen. nov. Sp. Nov., An alkaliphilic rod-to-coiled-shaped phototrophic heliobacterium from a siberian soda lake
PubMed:
Refined crystal structures of reaction centres from Rhodopseudomonas viridis in complexes with the herbicide atrazine and two chiral atrazine derivatives also lead to a new model of the bound carotenoid.
PubMed:
Evaluation of structurally different carotenoids in Escherichia coli transformants as protectants against UV-B radiation.
PubMed:
A higher-plant type zeta-carotene desaturase in the cyanobacterium Synechocystis PCC6803.
PubMed:
The major carotenoid in all known species of heliobacteria is the C30 carotenoid 4,4'-diaponeurosporene, not neurosporene.
PubMed:
The carotenoid 7,8-dihydro-psi end group can be cyclized by the lycopene cyclases from the bacterium Erwinia uredovora and the higher plant Capsicum annuum.
PubMed:
Expression, purification and properties of lycopene cyclase from Erwinia uredovora.
PubMed:
Purification in an active state and properties of the 3-step phytoene desaturase from Rhodobacter capsulatus overexpressed in Escherichia coli.
PubMed:
Biochemical characterization of purified zeta-carotene desaturase from Anabaena PCC 7120 after expression in Escherichia coli.
PubMed:
Carotenoid composition and vitamin A value of Brazilian loquat (Eriobotrya japonica Lindl.).
PubMed:
Molecular cloning and functional expression in E. coli of a novel plant enzyme mediating zeta-carotene desaturation.
PubMed:
A specific carotenoid is required for reconstitution of the Rubrivivax gelatinosus B875 light harvesting complex from its subunit form B820.
PubMed:
Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942.
PubMed:
Early steps in carotenoid biosynthesis: sequences and transcriptional analysis of the crtI and crtB genes of Rhodobacter sphaeroides and overexpression and reactivation of crtI in Escherichia coli and R. sphaeroides.
PubMed:
A novel carotenoid biosynthesis gene coding for zeta-carotene desaturase: functional expression, sequence and phylogenetic origin.
PubMed:
Functional complementation in Escherichia coli of different phytoene desaturase genes and analysis of accumulated carotenes.
PubMed:
Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli.
PubMed:
Photoisomerization of lycopene during carotenogenesis in mutant C-6D of Scenedesmus obliquus.
PubMed:
Evidence for an essential role of carotenoids in the assembly of an active photosystem II.
PubMed:
A Rhodobacter sphaeroides puf L, M and X deletion mutant and its complementation in trans with a 5.3 kb puf operon shuttle fragment.
PubMed:
The triterpenoid carotenoids and related terpenoids in Staphylococcus aureus 209P.
PubMed:
Reconstitution of carotenoids into the light-harvesting pigment-protein complex from the carotenoidless mutant of Rhodopseudomonas as sphaeroides R26.
PubMed:
Inhibition of carotenoid synthesis in Micrococcus roseus.
PubMed:
Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata.
PubMed:
The resonance Raman spectrum of carotenoids as an intrinsic probe for membrane potential. Oscillatory changes in the spectrum of neurosporene in the chromatophores of Rhodopseudomonas sphaeroides.
PubMed:
Biosynthesis of aryl carotenoids: inhibitor studies of chlorobactene biosynthesis in Chlorobium limicola f. thiosulfatophilum.
PubMed:
Carotenogenesis associated with arthrosporulation of Trichophyton mentagrophytes.
PubMed:
Studies on the near-UV effect on carotenogenesis in Verticillium agaricinum.
PubMed:
A series of mutant strains of Scenedesmus obliquus with abnormal carotenoid compositions.
PubMed:
The carotenoids of Flavobacterium strain R1560.
PubMed:
The carotenoid shift in Rhodopseudomonas sphaeroides. The flash induced change.
PubMed:
Enzymatic synthesis of C40 carotenes by cell-free preparation from Halobacterium cutirubrum.
PubMed:
An enzyme complex for the dehydrogenation of phytoene in Phycomyces.
PubMed:
[Effect of high pressure on the carotenoid content of Blakeslea trispora Thaxter mycelium].
PubMed:
Carotenoid pigments of Mycobacterium kansasii.
PubMed:
Triterpenoid carotenoids and related lipids. Triterpenoid monohydroxy- and monoglucosyloxy-carotenoids from Streptococcus faecium UNH 564P.
PubMed:
Triterpenoid carotenoids and related lipids. The triterpenoid carotenes of Streptococcus faecium UNH 564P.
PubMed:
Biosynthesis of carotenoids in Brevibacterium sp. KY-4313.
PubMed:
Biosynthesis of spheroidene and hydroxyspheroidene in Rhodopseudomonas species: experiments with nicotine as inhibitor.
PubMed:
[Light dependent carotenoid synthesis : VI. Time course of synthesis of various carotenoids in Fusarium aquaeductuum after various inductive treatments].
PubMed:
A novel sequence for phytoene dehydrogenation in Rhodospirillum rubrum.
PubMed:
Alternative pathways of spirilloxanthin biosynthesis in Rhodospirillum rubrum.
PubMed:
The stereospecific biosynthesis of phytoene and polyunsaturated carotenes.
PubMed:
BIOSYNTHESIS OF YEAST CAROTENOIDS.
PubMed:
Nonsaponifiable lipids of representative pleuropneumonia-like organisms.
PubMed:
[Identification of the major carotenoids of some fungi of the Ascomycetes and Basidiomycetes group. Neurosporene in Cantharellus infundibul informis].
PubMed:
On a cis-neurosporene ex Pyracantha and the in vitro; stereoisomerization of neurosporene.