neurosporene

psi,psi-carotene, 7,8-dihydro-

CAS: 502-64-7 C40 H58 MW: 538.90226000

Identification

Nameneurosporene
IUPAC(6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26,30-dodecaene
CAS Number502-64-7
FDA UNIISearch
Molecular FormulaC40 H58
Molecular Weight538.90226000
Nikkaji NumberJ367.196H

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 6.593e-014 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for neurosporene usage levels up tonot for fragrance use.
Recommendation for neurosporene flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

carrot root orange pericarp passion fruit pineapple fruit watermelon fruit

Synonyms

psi,psi- carotene, 7,8-dihydro- 7,8- dihydro-psi,psi-carotene (6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2,6,10,14,19,23,27,31- octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26,30-dodecaene PubMed: Effect of Illumination Intensity and Inhibition of Carotenoid Biosynthesis on Assembly of Peripheral Light-Gathering Complexes in Purple Sulfur Bacteria C Allochromatium vinosum ATCC 17899. PubMed: High carotenoid production by a halotolerant bacterium, Kocuria sp. strain QWT-12 and anticancer activity of its carotenoid. PubMed: Origin of the S* Excited State Feature of Carotenoids in Light-Harvesting Complex 1 from Purple Photosynthetic Bacteria. PubMed: Functional Lycopene Cyclase (CruA) in Cyanobacterium, Arthrospira platensis NIES-39, and its Role in Carotenoid Synthesis. PubMed: A metabolomic evaluation of the phytochemical composition of tomato juices being used in human clinical trials. PubMed: Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites. PubMed: Thermal processing differentially affects lycopene and other carotenoids in cis-lycopene containing, tangerine tomatoes. PubMed: Vibronic coupling in the excited-states of carotenoids. PubMed: Identification and spectroscopic characterization of neurosporene. PubMed: Enhanced bioavailability of lycopene when consumed as cis-isomers from tangerine compared to red tomato juice, a randomized, cross-over clinical trial. PubMed: Assembly of functional photosystem complexes in Rhodobacter sphaeroides incorporating carotenoids from the spirilloxanthin pathway. PubMed: Distribution of colored carotenoids between light-harvesting complexes in the process of recovering carotenoid biosynthesis in Ectothiorhodospira haloalkaliphila cells. PubMed: Multiple transformation with the crtYB gene of the limiting enzyme increased carotenoid synthesis and generated novel derivatives in Xanthophyllomyces dendrorhous. PubMed: Construction of carotenoid biosynthetic pathways using squalene synthase. PubMed: Dissection of tomato lycopene biosynthesis through virus-induced gene silencing. PubMed: Acyclic carotenoid and cyclic apocarotenoid cleavage by an orthologue of lignostilbene-α,β-dioxygenase in Rhodopseudomonas palustris. PubMed: Neurosporene is the major carotenoid accumulated by Rhodobacter viridis JA737. PubMed: New insight into the cleavage reaction of Nostoc sp. strain PCC 7120 carotenoid cleavage dioxygenase in natural and nonnatural carotenoids. PubMed: Heterologous carotenoid-biosynthetic enzymes: functional complementation and effects on carotenoid profiles in Escherichia coli. PubMed: High-level production of the industrial product lycopene by the photosynthetic bacterium Rhodospirillum rubrum. PubMed: Carotenogenesis gene cluster and phytoene desaturase catalyzing both three- and four-step desaturations from Rhodobacter azotoformans. PubMed: Rhodobacter viridis sp. nov., a phototrophic bacterium isolated from mud of a stream. PubMed: Elucidation of the biosynthetic pathway for Okenone in Thiodictyon sp. CAD16 leads to the discovery of two novel carotene ketolases. PubMed: Carotenoid radical formation: dependence on conjugation length. PubMed: Structural and kinetics properties of a mutated phytoene desaturase from Rubrivivax gelatinosus with modified product specificity. PubMed: Ultrafast time-resolved absorption spectroscopy of geometric isomers of carotenoids. PubMed: Ultrafast Time-resolved Absorption Spectroscopy of Geometric Isomers of Carotenoids. PubMed: Excitation energy transfer and carotenoid radical cation formation in light harvesting complexes - a theoretical perspective. PubMed: Carotenoids and carotenogenic genes in Podospora anserina: engineering of the carotenoid composition extends the life span of the mycelium. PubMed: Heterogeneity of carotenoid content and composition in LH2 of the purple sulphur bacterium Allochromatium minutissimum grown under carotenoid-biosynthesis inhibition. PubMed: Isorenieratene biosynthesis in green sulfur bacteria requires the cooperative actions of two carotenoid cyclases. PubMed: Ultrafast time-resolved carotenoid to-bacteriochlorophyll energy transfer in LH2 complexes from photosynthetic bacteria. PubMed: Mutation of a single residue, beta-glutamate-20, alters protein-lipid interactions of light harvesting complex II. PubMed: Culture characteristics of carotenoid-producing filamentous fungus T-1, and carotenoid production. PubMed: Evaluation of colors in green mutants isolated from purple bacteria as a host for colorimetric whole-cell biosensors. PubMed: Role of B800 in carotenoid-bacteriochlorophyll energy and electron transfer in LH2 complexes from the purple bacterium Rhodobacter sphaeroides. PubMed: Ultrafast dynamics and excited state spectra of open-chain carotenoids at room and low temperatures. PubMed: Kinetic variations determine the product pattern of phytoene desaturase from Rubrivivax gelatinosus. PubMed: Carotenoid radical cation formation in LH2 of purple bacteria: a quantum chemical study. PubMed: Astaxanthin formation in the marine photosynthetic bacterium Rhodovulum sulfidophilum expressing crtI, crtY, crtW and crtZ. PubMed: Mechanism of carotenoid singlet excited state energy transfer in modified bacterial reaction centers. PubMed: Sll0254 (CrtL(diox)) is a bifunctional lycopene cyclase/dioxygenase in cyanobacteria producing myxoxanthophyll. PubMed: Investigation of the effects of different carotenoids on the absorption and CD signals of light harvesting 1 complexes. PubMed: Monocyclic carotenoid biosynthetic pathway in the yeast Phaffia rhodozyma (Xanthophyllomyces dendrorhous). PubMed: Efficient light harvesting through carotenoids. PubMed: Accumulation of unusual carotenoids in the spheroidene pathway, demethylspheroidene and demethylspheroidenone, in an alkaliphilic purple nonsulfur bacterium Rhodobaca bogoriensis. PubMed: Effects of carotenoid inhibition on the photosynthetic RC-LH1 complex in purple sulphur bacterium Thiorhodospira sibirica. PubMed: Construction and characterization of genetically modified synechocystis sp. PCC 6803 photosystem II core complexes containing carotenoids with shorter pi-conjugation than beta-carotene. PubMed: [Isoprenoid pigments in representatives of the family Microbacteriaceae]. PubMed: Photo-oxidative stress in Rhodobacter sphaeroides: protective role of carotenoids and expression of selected genes. PubMed: Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde. PubMed: Analysis in vitro of the enzyme CRTISO establishes a poly-cis-carotenoid biosynthesis pathway in plants. PubMed: Elimination of polarity in the carotenoid terminus promotes the exposure of B850-binding sites (Tyr 44, 45) and ANS-mediated energy transfer in LH2 complexes of Rhodobacter sphaeroides. PubMed: Conjugation length dependence of internal conversion in carotenoids: role of the intermediate state. PubMed: zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene. PubMed: Acquirement and characterization of a carotenoid mutant (GM309) of Rhodobacter sphaeroides 601. PubMed: Slr1293 in Synechocystis sp. strain PCC 6803 Is the C-3',4' desaturase (CrtD) involved in myxoxanthophyll biosynthesis. PubMed: Asymmetrically acting lycopene beta-cyclases (CrtLm) from non-photosynthetic bacteria. PubMed: Role of the C-terminal extrinsic region of the alpha polypeptide of the light-harvesting 2 complex of Rhodobacter sphaeroides: a domain swap study. PubMed: Response of Escherichia coli Containing Mycobacterial Carotene Genes to UV Radiation. PubMed: Chemistry, distribution, and metabolism of tomato carotenoids and their impact on human health. PubMed: Carotenoid composition and vitamin A value of an Argentinian squash (Cucurbita moschata). PubMed: Functional assembly of the foreign carotenoid lycopene into the photosynthetic apparatus of Rhodobacter sphaeroides, achieved by replacement of the native 3-step phytoene desaturase with its 4-step counterpart from Erwinia herbicola. PubMed: Tangerine dreams: cloning of carotenoid isomerase from Arabidopsis and tomato. PubMed: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase. PubMed: Phytoene desaturase, CrtI, of the purple photosynthetic bacterium, Rubrivivax gelatinosus, produces both neurosporene and lycopene. PubMed: Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution. PubMed: Biosynthesis of carotenoids in plastids of plants. PubMed: A single five-step desaturase is involved in the carotenoid biosynthesis pathway to beta-carotene and torulene in Neurospora crassa. PubMed: Carotenoid and ultrastructure variations in plastids of Arum italicum Miller fruit during maturation and ripening. PubMed: Substrate specificity of the expressed carotenoid 3,4-desaturase from Rubrivivax gelatinosus reveals the detailed reaction sequence to spheroidene and spirilloxanthin. PubMed: Catalytic properties of an expressed and purified higher plant type zeta-carotene desaturase from Capsicum annuum. PubMed: Heliorestis daurensis, gen. nov. Sp. Nov., An alkaliphilic rod-to-coiled-shaped phototrophic heliobacterium from a siberian soda lake PubMed: Refined crystal structures of reaction centres from Rhodopseudomonas viridis in complexes with the herbicide atrazine and two chiral atrazine derivatives also lead to a new model of the bound carotenoid. PubMed: Evaluation of structurally different carotenoids in Escherichia coli transformants as protectants against UV-B radiation. PubMed: A higher-plant type zeta-carotene desaturase in the cyanobacterium Synechocystis PCC6803. PubMed: The major carotenoid in all known species of heliobacteria is the C30 carotenoid 4,4'-diaponeurosporene, not neurosporene. PubMed: The carotenoid 7,8-dihydro-psi end group can be cyclized by the lycopene cyclases from the bacterium Erwinia uredovora and the higher plant Capsicum annuum. PubMed: Expression, purification and properties of lycopene cyclase from Erwinia uredovora. PubMed: Purification in an active state and properties of the 3-step phytoene desaturase from Rhodobacter capsulatus overexpressed in Escherichia coli. PubMed: Biochemical characterization of purified zeta-carotene desaturase from Anabaena PCC 7120 after expression in Escherichia coli. PubMed: Carotenoid composition and vitamin A value of Brazilian loquat (Eriobotrya japonica Lindl.). PubMed: Molecular cloning and functional expression in E. coli of a novel plant enzyme mediating zeta-carotene desaturation. PubMed: A specific carotenoid is required for reconstitution of the Rubrivivax gelatinosus B875 light harvesting complex from its subunit form B820. PubMed: Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942. PubMed: Early steps in carotenoid biosynthesis: sequences and transcriptional analysis of the crtI and crtB genes of Rhodobacter sphaeroides and overexpression and reactivation of crtI in Escherichia coli and R. sphaeroides. PubMed: A novel carotenoid biosynthesis gene coding for zeta-carotene desaturase: functional expression, sequence and phylogenetic origin. PubMed: Functional complementation in Escherichia coli of different phytoene desaturase genes and analysis of accumulated carotenes. PubMed: Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli. PubMed: Photoisomerization of lycopene during carotenogenesis in mutant C-6D of Scenedesmus obliquus. PubMed: Evidence for an essential role of carotenoids in the assembly of an active photosystem II. PubMed: A Rhodobacter sphaeroides puf L, M and X deletion mutant and its complementation in trans with a 5.3 kb puf operon shuttle fragment. PubMed: The triterpenoid carotenoids and related terpenoids in Staphylococcus aureus 209P. PubMed: Reconstitution of carotenoids into the light-harvesting pigment-protein complex from the carotenoidless mutant of Rhodopseudomonas as sphaeroides R26. PubMed: Inhibition of carotenoid synthesis in Micrococcus roseus. PubMed: Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata. PubMed: The resonance Raman spectrum of carotenoids as an intrinsic probe for membrane potential. Oscillatory changes in the spectrum of neurosporene in the chromatophores of Rhodopseudomonas sphaeroides. PubMed: Biosynthesis of aryl carotenoids: inhibitor studies of chlorobactene biosynthesis in Chlorobium limicola f. thiosulfatophilum. PubMed: Carotenogenesis associated with arthrosporulation of Trichophyton mentagrophytes. PubMed: Studies on the near-UV effect on carotenogenesis in Verticillium agaricinum. PubMed: A series of mutant strains of Scenedesmus obliquus with abnormal carotenoid compositions. PubMed: The carotenoids of Flavobacterium strain R1560. PubMed: The carotenoid shift in Rhodopseudomonas sphaeroides. The flash induced change. PubMed: Enzymatic synthesis of C40 carotenes by cell-free preparation from Halobacterium cutirubrum. PubMed: An enzyme complex for the dehydrogenation of phytoene in Phycomyces. PubMed: [Effect of high pressure on the carotenoid content of Blakeslea trispora Thaxter mycelium]. PubMed: Carotenoid pigments of Mycobacterium kansasii. PubMed: Triterpenoid carotenoids and related lipids. Triterpenoid monohydroxy- and monoglucosyloxy-carotenoids from Streptococcus faecium UNH 564P. PubMed: Triterpenoid carotenoids and related lipids. The triterpenoid carotenes of Streptococcus faecium UNH 564P. PubMed: Biosynthesis of carotenoids in Brevibacterium sp. KY-4313. PubMed: Biosynthesis of spheroidene and hydroxyspheroidene in Rhodopseudomonas species: experiments with nicotine as inhibitor. PubMed: [Light dependent carotenoid synthesis : VI. Time course of synthesis of various carotenoids in Fusarium aquaeductuum after various inductive treatments]. PubMed: A novel sequence for phytoene dehydrogenation in Rhodospirillum rubrum. PubMed: Alternative pathways of spirilloxanthin biosynthesis in Rhodospirillum rubrum. PubMed: The stereospecific biosynthesis of phytoene and polyunsaturated carotenes. PubMed: BIOSYNTHESIS OF YEAST CAROTENOIDS. PubMed: Nonsaponifiable lipids of representative pleuropneumonia-like organisms. PubMed: [Identification of the major carotenoids of some fungi of the Ascomycetes and Basidiomycetes group. Neurosporene in Cantharellus infundibul informis]. PubMed: On a cis-neurosporene ex Pyracantha and the in vitro; stereoisomerization of neurosporene.