ayapin
Identification
| Name | ayapin |
| IUPAC | [1,3]dioxolo[4,5-g]chromen-6-one |
| CAS Number | 494-56-4 |
| FDA UNII | 7Y9JR4973B |
| Molecular Formula | C10 H6 O4 |
| Molecular Weight | 190.15462000 |
| Nikkaji Number | J11.816H |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2218 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ayapin usage levels up to | not for fragrance use. |
| Recommendation for ayapin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
6H-1,3-
dioxolo(4,5-g)(1)benzopyran-6-one
[1,3]
dioxolo[4,5-g]chromen-6-one
6,7-(
methylene dioxy) coumarin
6,7-(
methylenedioxy)coumarin
PubMed:
[Study on distributed patterns of scoparone and ayapin in Dendrobium species from Yunnan].
PubMed:
Huperzine A for mild cognitive impairment.
PubMed:
[Aromatic constituents of Heteroplexis micocephal and their bioactivities].
PubMed:
Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells.
PubMed:
Huperzine A for vascular dementia.
PubMed:
Antifungal activity of a new phenolic compound from capitulum of a head rot-resistant sunflower genotype.
PubMed:
Simultaneous analysis of trans- and cis-isomers of 2-glucosyloxycinnamic acids and coumarin derivatives in Dendrobium thyrsiflorum by high-performance liquid chromatography (HPLC)-photodiode array detection (DAD)-electrospray ionization (ESI)-tandem mass spectrometry (MS).
PubMed:
Antifungal activity of some coumarins obtained from species of Pterocaulon (Asteraceae).
PubMed:
Yb(OTf)3-catalyzed reactions of 5-alkylidene Meldrum's acids with phenols: one-pot assembly of 3,4-dihydrocoumarins, 4-chromanones, coumarins, and chromones.
PubMed:
Diterpenes from Alomia myriadenia (Asteraceae) with cytotoxic and trypanocidal activity.
PubMed:
[Studies on the chemical constituents of Dendrobium fimbriatum].
PubMed:
Systemic acquired resistance in sunflower (Helianthus annuus L.).
PubMed:
Atom economy. Palladium-catalyzed formation of coumarins by addition of phenols and alkynoates via a net C-H insertion.
PubMed:
New coumarins from Pterocaulon polystachyum.
PubMed:
The metabolism of sunflower phytoalexins ayapin and scopoletin: plant-fungus interactions.
PubMed:
[Blood coagulation activity of the Ayapin, (6,7-metilen-dioxy-coumarin) obtained from Alomia fastigiata Benth (Compositae)].
PubMed:
ACCUMULATION OF AYAPIN AND SCOPOLIN IN SUNFLOWER PLANTS TREATED WITH 2,4-DICHLOROPHENOXYACETIC ACID.
PubMed:
Ayapin, scopoletin and 6,7-dimethoxycoumarin from Dendrobium thyrsiflorum (Reichb. f.).