Identification

Nameethylene oxide
IUPACoxirane
CAS Number75-21-8
EINECS200-849-9
FDA UNIIJJH7GNN18P
Molecular FormulaC2 H4 O
Molecular Weight44.05308000
MDL NumberMFCD00014482
Nikkaji NumberJ1.942I
Beilstein0102378

Regulatory

DG SANTE Food Contact Materialsethylene oxide
FEMA Number2433-VOID
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)75-21-8 ; ETHYLENE OXIDE--NLFG
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless gas (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.88200 @ 25.00 °C.
Refractive Index 1.35970 @ 20.00 °C.
Melting Point -111.00 °C. @ 760.00 mm Hg
Boiling Point 10.00 to 11.00 °C. @ 760.00 mm Hg
Vapor Pressure 1310.000000 mmHg @ 25.00 °C.
Flash Point -56.00 °F. TCC ( -49.00 °C. ) (est)
logP (o/w) -0.300
Soluble in water, 2.374e+005 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesnot used anymore

No sensory data available

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 72 mg/kg
Dermal Toxicitysubcutaneous-rat LD50 187 mg/kg
Inhalation Toxicityinhalation-rat LC50 800 ppm/4H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorymultipurpose additives
Recommendation for ethylene oxide usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

No supplier data available

Potential Uses

bactericidal disinfectants fungicidal sporicidal

Natural Occurrence

not found in nature

Synonyms

amprolene anprolene anproline oxa cyclopropane dihydrooxirene dimethylene oxide 1,2- epoxyaethan epoxyethane 1,2- epoxyethane oxido ethane ethene oxide ethox ethyleneoxide merpol oxide, ethylene oxiran oxirane oxirene, dihydro- oxyfume qazi-ketcham PubMed: Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity. PubMed: A novel aqueous two phase system composed of a thermo-separating polymer and an organic solvent for purification of thermo-acidic amylase enzyme from red pitaya (Hylocereus polyrhizus) peel. PubMed: Liquid crystalline assembly of coil-rod-coil molecules with lateral methyl groups into 3-D hexagonal and tetragonal assemblies. PubMed: Identification of ethylene oxide in herbs, spices and other dried vegetables imported into Italy. PubMed: Online dynamic pH junction-sweeping for the determination of benzoic and sorbic acids in food products by capillary electrophoresis. PubMed: In vivo evaluation of mastication noise reduction for dual channel implantable microphone. PubMed: Encapsulation of T4 bacteriophage in electrospun poly(ethylene oxide)/cellulose diacetate fibers. PubMed: Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing "Generally Recognized As Safe" (GRAS) nanopharmaceuticals: A review. PubMed: The mechanism of starch granule reacted with OSA by phase transition catalyst in aqueous medium. PubMed: Fabrication, gastromucoadhesivity, swelling, and degradation of zein-chitosan composite ultrafine fibers. PubMed: Fast screening of rice knockout mutants by multi-channel microchip electrophoresis. PubMed: Encapsulation of folic acid and its stability in sodium alginate-pectin-poly(ethylene oxide) electrospun fibres. PubMed: Evaluation of intraocular reactivity to metallic and ethylene oxide contaminants of medical devices in a rabbit model. 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PubMed: Gas chromatographic determination with electron capture detection of residual ethylene oxide in intraocular lenses. PubMed: NTP Toxicology and Carcinogenesis Studies of Ethylene Oxide (CAS No. 75-21-8) in B6C3F1 Mice (Inhalation Studies). PubMed: 2-chloroethyl fatty acid esters as indicators of 2-chloroethanol in black walnuts, seasoning mixes, and spices. PubMed: Anaphylactic shock caused by formaldehyde in a patient undergoing long-term hemodialysis. PubMed: Frequency, size and location of brain tumours in F-344 rats chronically exposed to ethylene oxide. PubMed: Mutation and enhanced virus transformation of cultured hamster cells by exposure to gaseous ethylene oxide. PubMed: Three cases of hemodialysis-associated hypersensitivity reactions. PubMed: Ethylene oxide. PubMed: Biomonitoring of exposure to potential mutagens and carcinogens in industrial populations. PubMed: Capsicum production, technology, chemistry, and quality. 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PubMed: OBSERVATIONS ON AUTOCLAVED, FUMIGATED AND IRRADIATED DIETS FOR BREEDING MICE. PubMed: Fumigation of jute bags with ethylene oxide and methyl bromide to eradicate potato ring rot bacteria.