isopropyl formate
formic acid, isopropyl ester
Identification
| Name | isopropyl formate |
| IUPAC | propan-2-yl formate |
| CAS Number | 625-55-8 |
| EINECS | 210-901-2 |
| FDA UNII | H1L164W42G |
| Molecular Formula | C4 H8 O2 |
| Molecular Weight | 88.10616000 |
| MDL Number | MFCD00014127 |
| Nikkaji Number | J53.981C |
| Beilstein | 1735844 |
| CoE Number | 503 |
Regulatory
| JECFA Food Flavoring | 304 isopropyl formate |
| DG SANTE Food Flavourings | 09.165 isopropyl formate |
| FEMA Number | 2944 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 625-55-8 ; ISOPROPYL FORMATE |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | colorless clear liquid (est) |
| Assay | 97.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | -80.00 °C. @ 760.00 mm Hg |
| Boiling Point | 67.00 to 70.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 127.065002 mmHg @ 25.00 °C. (est) |
| Flash Point | 7.00 °F. TCC ( -13.89 °C. ) |
| logP (o/w) | 0.730 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
| Similar Items | note |
Organoleptic Properties
| Odor Strength | medium , |
| Substantivity | < 1 hour(s) at 100.00 % |
| Odor Description |
at 10.00 % in dipropylene glycol. Sweet, etherial, solvent like with a fruity lift
|
| Odor sample from | Sigma-Aldrich |
| Taste Description | at 35.00 ppm. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 4300 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for isopropyl formate usage levels up to | 2.0000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.45 (μg/capita/day) |
| baked goods | 60.00000 |
| beverages(nonalcoholic) | 18.00000 |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 18.00000 |
| fruit ices | 18.00000 |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | 55.00000 |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Synerzine, Inc.
Innovation. Customization. Aroma Ingredients.
Synerzine is a leading supplier of flavor and fragrance ingredients.
Potential Uses
Natural Occurrence
Synonyms
formic acid 1-methyl ethyl ester
formic acid 1-methylethyl ester
formic acid isopropyl ester
formic acid, 1-methylethyl ester
formic acid, isopropyl ester
1-
methyl ethyl formate
1-
methylethyl formate
propan-2-yl formate
iso
propyl methanoate
iso-
propyl-formate
iso
propylformate
PubMed:
Application of acid-catalyzed hydrolysis of dispersed organic solvent in developing new microencapsulation process technology.
PubMed:
Investigation on structural integrity of PLGA during ammonolysis-based microencapsulation process.
PubMed:
Nonhalogenated solvent-based solvent evaporation process useful in preparation of PLGA microspheres.
PubMed:
Ammonolysis-based microencapsulation technique using isopropyl formate as dispersed solvent.