2,4-dimethyl-5-ethyl thiazole

thiazole, 2,4-dimethyl-5-ethyl-

CAS: 38205-61-7 C7 H11 N S MW: 141.23667000 nutty

Identification

Name2,4-dimethyl-5-ethyl thiazole
IUPAC5-ethyl-2,4-dimethyl-1,3-thiazole
CAS Number38205-61-7
EINECS253-827-6
FDA UNII3836EZK8C1
Molecular FormulaC7 H11 N S
Molecular Weight141.23667000
Nikkaji NumberJ108.853J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 199.00 to 200.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.484000 mmHg @ 25.00 °C. (est)
Flash Point 161.00 °F. TCC ( 71.67 °C. )
logP (o/w) 1.361 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description at 0.01 % in propylene glycol.

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 2,4-dimethyl-5-ethyl thiazole usage levels up tonot for fragrance use.
Recommendation for 2,4-dimethyl-5-ethyl thiazole flavor usage levels up tonot for flavor use.

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Potential Uses

FL nut

Natural Occurrence

beef roast beef PMC chicken fried chicken PMC coffee PMC peanut roasted peanut pork cooked pork PMC

Synonyms

2,4- dimethyl-5-ethylthiazole ethyl dimethyl thiazole 5- ethyl-2,4-dimethyl thiazole 5- ethyl-2,4-dimethyl-1,3-thiazole 5- ethyl-2,4-dimethylthiazole thiazole, 2,4-dimethyl-5-ethyl- thiazole, 5-ethyl-2,4-dimethyl- PubMed: Synthesis and antimicrobial activity of some new heterocycles incorporating the pyrazolopyridine moiety. PubMed: Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans. PubMed: Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine. PubMed: Blockade of Tau hyperphosphorylation and Aβ₁₋₄₂ generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ₁ receptor agonist, in a nontransgenic mouse model of Alzheimer's disease. PubMed: Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities. PubMed: Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. PubMed: Novel rhodanine derivatives induce growth inhibition followed by apoptosis. PubMed: Design, microwave-assisted synthesis and HIV-RT inhibitory activity of 2-(2,6-dihalophenyl)-3-(4,6-dimethyl-5-(un)substituted-pyrimidin-2-yl)thiazolidin-4-ones. PubMed: The antipsychotics clozapine and olanzapine increase plasma glucose and corticosterone levels in rats: comparison with aripiprazole, ziprasidone, bifeprunox and F15063. PubMed: 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. PubMed: Comparison of three lychee cultivar odor profiles using gas chromatography-olfactometry and gas chromatography-sulfur detection. PubMed: Anxiety and depression. PubMed: Nature and significance of the electron-dense bodies of the endospores of rhinosporidium seeberi: their reactions with MTT (3-[4,5-dimethyl-2-thiazolyl]-2,5-diphenyl-2H-tetrazolium bromide) and TMRE (tetramethyl-rhodamine ethyl ester). PubMed: The assessment of the viability of the endospores of Rhinosporidium seeberi with MTT (3-[4, 5-dimethyl-2-thiazolyl]-2, 5-diphenyl-2H-tetrazolium bromide). PubMed: Attempted reduction of 1,2,3-thiadiazole-4-carboxylates with samarium/iodine in methanol. Unexpected ring enlargement to 1,2,5-trithiepan-4,6-dicarboxylates. PubMed: Structure-activity relationships of 2-aminothiazole derivatives as inducible nitric oxide synthase inhibitor. PubMed: Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. PubMed: Sequence specificity of DNA alkylation by the antitumor natural product leinamycin. PubMed: CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans. PubMed: A neutral complex of an azino[bond]DTDAF compound with TCNQ. PubMed: Analysis and detection of the herbicides dimethenamid and flufenacet and their sulfonic and oxanilic acid degradates in natural water. PubMed: The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK(1) receptor. PubMed: Characterisation of the effects of SR146131, a novel non-peptide CCK(1) receptor agonist, on IMR-32 human neuroblastoma cells. PubMed: Interaction of cyanine dyes with nucleic acids. XVII. Towards an aggregation of cyanine dyes in solutions as a factor facilitating nucleic acid detection. PubMed: Essential role of extracellular charged residues of the human CCK(1) receptor for interactions with SR 146131, SR 27897 and CCK-8S. PubMed: Effects of CP-060S, a novel Ca(2+) channel blocker, on oxidative stress in cultured cardiac myocytes. PubMed: Contrasting roles of leu(356) in the human CCK(1) receptor for antagonist SR 27897 and agonist SR 146131 binding. PubMed: Participation of peroxidase reaction in thiamine catabolism. PubMed: Discriminative stimulus properties of the 5-HT1A receptor agonist BAY x 3702 in the rat. PubMed: Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets. PubMed: Synthesis and antimicrobial screening of some novel thiazoles, dithiazoles and thiazolylpyridines. PubMed: Structure optimization of a leukotriene D4 antagonist by combinatorial chemistry in solution. PubMed: Subclassification of release-regulating alpha 2-autoreceptors in human brain cortex. PubMed: Presynaptic alpha 2-adrenoceptors mediating inhibition of noradrenaline and 5-hydroxytryptamine release in rat cerebral cortex: further characterization as different alpha 2-adrenoceptor subtypes. PubMed: Evidence for participation of transglutaminase in receptor-mediated endocytosis. PubMed: The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays.