4-methyl guaiacol
phenol, 2-methoxy-4-methyl-
Identification
| Name | 4-methyl guaiacol |
| IUPAC | 2-methoxy-4-methylphenol |
| CAS Number | 93-51-6 |
| EINECS | 202-252-9 |
| FDA UNII | W9GW1KZG6N |
| Molecular Formula | C8 H10 O2 |
| Molecular Weight | 138.16610000 |
| MDL Number | MFCD00002378 |
| Nikkaji Number | J1.175D |
| Beilstein | 1862340 |
| CoE Number | 175 |
| XlogP3 | 1.30 (est) |
Regulatory
| JECFA Food Flavoring | 715 2-methoxy-4-methylphenol |
| DG SANTE Food Flavourings | 04.007 2-methoxy-4-methylphenol |
| FEMA Number | 2671 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 93-51-6 ; 2-METHOXY-4-METHYLPHENOL |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | pale yellow clear liquid (est) |
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.09000 to 1.10000 @ 25.00 °C. |
| Pounds per Gallon - (est). | 9.070 to 9.153 |
| Refractive Index | 1.53400 to 1.54000 @ 20.00 °C. |
| Melting Point | 5.00 °C. @ 760.00 mm Hg |
| Boiling Point | 221.00 to 222.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.078000 mmHg @ 25.00 °C. (est) |
| Flash Point | 211.00 °F. TCC ( 99.44 °C. ) |
| logP (o/w) | 1.925 (est) |
| Shelf Life | 24.00 month(s) or longer if stored properly. |
| Storage | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in | alcohol |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
Organoleptic Properties
| Odor Strength | medium , |
| Substantivity | 132 hour(s) at 10.00 % in dipropylene glycol |
| Odor Description |
at 10.00 % in dipropylene glycol. at 1.00 % in ethyl alcohol. carnation; cheese; chocolate; clove; jasmine; sweet; vanilla; meaty; woody; wine-like; green; smoky; coffee sweet, spicy/phenolic vanilla sweet-spicy, phenolic-leathery note, floral balsamic undertones aromatic, spicy, clove, vanilla, phenolic, smoke-like sweet, smoky, leathery fragrance with hints of vanilla and cloves
|
| Odor sample from | Advanced Biotech. Inc. |
| Taste Description |
spicy clove woody leathery smoky coffee phenolic cocoa burnt at 10.00 ppm. spicy phenolic, smoky, sweet, coffee, vanilla, cocoa spicy, medicinal; vanilla, clove-like with phenolic nuances
|
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 740 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| IFRA Critical Effect | Dermal sensitization |
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%) | Category 1: Products applied to the lips |
| Notes | IFRA FLAVOR REQUIREMENTS: |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 31.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 3.00 (μg/capita/day) |
| baked goods | 4.00000 |
| beverages(nonalcoholic) | 10.00000 |
| beverages(alcoholic) | 0.60000 |
| breakfast cereal | - |
| cheese | - |
| chewing gum | 15.00000 |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 1.00000 |
| fruit ices | - |
| gelatins / puddings | 7.00000 |
| granulated sugar | - |
| gravies | - |
| hard candy | 0.80000 |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | 12.00000 |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | 4.00000 |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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