coronopilin

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1,6-beta-dihydroxy-4-oxo-10-alpha-h-ambros-11(13)-en-12-oic acid gamma-lactone

CAS: 2571-81-5 C15 H20 O4 MW: 264.32120000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namecoronopilin
IUPAC(3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylidene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione
CAS Number2571-81-5
FDA UNIISearch
Molecular FormulaC15 H20 O4
Molecular Weight264.32120000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1.245e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for coronopilin usage levels up tonot for fragrance use.
Recommendation for coronopilin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

parthenium hysterophorus

Synonyms

10-alpha-H- ambros-11(13)-en-12-oic acid, 1,6-beta-dihydroxy-4-oxo-, gamma-lactone azuleno(4,5-b)furan-2,9-dione, decahydro-6a-hydroxy-6,9a-dimethyl-3-methylene-, (3aS-(3aalpha,6beta,6aalpha,9abeta,9balpha))- (9CI) coronopolin 1,6-beta- dihydroxy-4-oxo-10-alpha-h-ambros-11(13)-en-12-oic acid gamma-lactone (3aS,6S,6aS,9aS,9bR)-6a- hydroxy-6,9a-dimethyl-3-methylidene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione PubMed: Design and synthesis of novel 1,2,3-triazole derivatives of coronopilin as anti-cancer compounds. PubMed: Multiple anticancer effects of damsin and coronopilin isolated from Ambrosia arborescens on cell cultures. PubMed: Quantification of sesquiterpene lactones in Parthenium hyterophorous by normal-phase HPLC. PubMed: Effect of sesquiterpene lactone coronopilin on leukaemia cell population growth, cell type-specific induction of apoptosis and mitotic catastrophe. PubMed: A new highly oxygenated pseudoguaianolide from a collection of the flowers of Parthenium hysterophorus. PubMed: Pseudoguaianolides from the flowers of Parthenium hysterophorus.