ethyl gallate

gallic acid, ethyl ester

CAS: 831-61-8 C9 H10 O5 MW: 198.17470000

Identification

Nameethyl gallate
IUPACethyl 3,4,5-trihydroxybenzoate
CAS Number831-61-8
EINECS212-608-5
FDA UNII235I6UDD3L
Molecular FormulaC9 H10 O5
Molecular Weight198.17470000
MDL NumberMFCD00016430
Beilstein2116014
XlogP31.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 447.28 °C. @ 760.00 mm Hg (est)
Flash Point 365.00 °F. TCC ( 185.00 °C. ) (est)
logP (o/w) 1.300
Soluble in water, 1.319e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD50 5810 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for ethyl gallate usage levels up tonot for fragrance use.
Recommendation for ethyl gallate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

guava root not found in nature

Synonyms

benzoic acid, 3,4,5-trihydroxy-, ethyl ester ethyl 3,4,5-trihydroxybenzoate ethyl-3,4,5-trihydroxybenzoate ethylgallate gallic acid ethyl ester gallic acid, ethyl ester nipa no. 48 nipagallin A phyllemblin progallin A 3,4,5- trihydroxybenzoic acid ethyl ester PubMed: Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour. Fen Ke) seed extract. PubMed: Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. PubMed: Synthesis, biological evaluation and docking studies of 4-aryloxymethyl coumarins derived from substructures and degradation products of vancomycin. PubMed: Ethyl gallate attenuates acute lung injury through Nrf2 signaling. PubMed: Looking like Limulus? - Retinula axons and visual neuropils of the median and lateral eyes of scorpions. PubMed: [Phenolic constituents of Ampelopsis grossedentata from zhangjiajie]. PubMed: [Study on chemical constituents from flowers of Ailanthus altissima]. PubMed: Protective effect of Paeonia anomala extracts and constituents against tert-butylhydroperoxide-induced oxidative stress in HepG2 cells. PubMed: Glyoxal and methylglyoxal: autoxidation from dihydroxyacetone and polyphenol cytoprotective antioxidant mechanisms. PubMed: Ethyl Gallate Induces Apoptosis of HL-60 Cells by Promoting the Expression of Caspases-8, -9, -3, Apoptosis-Inducing Factor and Endonuclease G. PubMed: [Phenolic acid derivatives from Alchornea trewioides]. PubMed: Synergy study of the inhibitory potential of red wine polyphenols on vascular smooth muscle cell proliferation. PubMed: Identifying new lignin bioengineering targets: impact of epicatechin, quercetin glycoside, and gallate derivatives on the lignification and fermentation of maize cell walls. PubMed: Antibacterial activity of wine phenolic compounds and oenological extracts against potential respiratory pathogens. PubMed: Free radical scavenging, cytotoxic, and hemolytic activities of an active antioxidant compound ethyl gallate from leaves of Acacia nilotica (L.) Wild. Ex. Delile subsp. indica (Benth.) Brenan. PubMed: Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs. PubMed: Bioactive constituents from Harpephyllum caffrum Bernh. and Rhus coriaria L. PubMed: Gallic treatment is galling to Pseudomonas. PubMed: Mechanisms of systemic vasodilation by lysozyme-c in septic shock. PubMed: [Chemical constituents from the roots of Pithecellobium lucidum and their cytotoxic activity]. PubMed: Benefits of ethyl gallate versus norepinephrine in the treatment of cardiovascular collapse in Pseudomonas aeruginosa septic shock in dogs. PubMed: [Phenolic acid derivatives from Bauhinia glauca subsp. pernervosa]. PubMed: Involvement of heme oxygenase-1 induction in inhibitory effect of ethyl gallate isolated from Galla Rhois on nitric oxide production in RAW 264.7 macrophages. PubMed: Ethyl gallate isolated from Pistacia integerrima Linn. inhibits cell adhesion molecules by blocking AP-1 transcription factor. PubMed: [Study on the chemical constituents from fresh roots of Euphorbia fischeriana]. PubMed: Revisiting the anatomy of the central nervous system of a hemimetabolous model insect species: the pea aphid Acyrthosiphon pisum. PubMed: Ethyl gallate, a scavenger of hydrogen peroxide that inhibits lysozyme-induced hydrogen peroxide signaling in vitro, reverses hypotension in canine septic shock. PubMed: Partial least squares and principal components analysis of wine vintage by high performance liquid chromatography with chemiluminescence detection. PubMed: [Chemical constituents from stem barks of Vernonia cumingiana]. PubMed: Cell death shapes embryonic lineages of the central complex in the grasshopper Schistocerca gregaria. PubMed: Sexual dimorphism in shape and distribution of GABA-like immuno-reactive neurons in cricket terminal abdominal ganglion. PubMed: Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD. PubMed: In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. PubMed: [Chemical constituents from roots of Distylium myricoides]. PubMed: LC-MS/MS method for the simultaneous determination of ethyl gallate and its major metabolite in rat plasma. PubMed: Constancy and variability of identified glomeruli in antennal lobes: computational approach in Spodoptera littoralis. PubMed: Validated HPLC method for the standardization of Phyllanthus niruri (herb and commercial extracts) using corilagin as a phytochemical marker. PubMed: [Studies on chemical constituents from leaves of Lysidice brevicalyx]. PubMed: [Studies on chemical constituents of Salacia prinoides]. PubMed: A redetermination of 2-(6-diethyl-amino-3-diethyl-iminio-3H-xanthen-9-yl)benzoate-ethyl gallate (1/1) at room temperature. PubMed: Antioxidant constituents of Nymphaea caerulea flowers. PubMed: Antiplasmodial phenolic compounds from Piptadenia pervillei. PubMed: Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction. PubMed: A new benzofuranic acid from the leaves of Rhus alata. PubMed: A low-temperature phase of the 1:1 complex of 2-(6-diethylamino-3-diethyl-iminio-3H-xanthen-9-yl)benzoate with ethyl gallate at 93 K. PubMed: A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. PubMed: Antioxidant activity of brocchlin carboxylic acid and its methyl ester from Chrozophora brocchiana. PubMed: Antibacterial phenolic compounds from the spines of Gleditsia sinensis Lam. PubMed: [Chemical constitutents of Bauhinia aurea]. PubMed: Phosphodiesterase-I inhibitor quinovic acid glycosides from Bridelia ndellensis. PubMed: Isolation of the active compound in Mauria heterophylla, a Peruvian plant with antibacterial activity. PubMed: Effects of structure on radical-scavenging abilities and antioxidative activities of tea polyphenols: NMR analytical approach using 1,1-diphenyl-2-picrylhydrazyl radicals. PubMed: Alkyl gallates, intensifiers of beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus. PubMed: Biological activity of phenolic compounds from Alchornea glandulosa. PubMed: [Studies on the chemical constituents of Ampelopsis humulifolia var. heterophylla (Thunb.) K. Koch]. PubMed: Antioxidant flavonoids and phenolic acids from leaves of Leea guineense G Don (Leeaceae). PubMed: Two new and four known polyphenolics obtained as new cell-cycle inhibitors from Rubus aleaefolius Poir. PubMed: GC-mS analysis and anti-microbial activity of acidic fractions obtained from Paeonia peregrina and Paeonia tenuifolia roots. PubMed: Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit. PubMed: Pharmacologically active ellagitannins from Terminalia myriocarpa. PubMed: Deodorizing effects of tea catechins on amines and ammonia. PubMed: Analytical method of measuring tea catechins in human plasma by solid-phase extraction and HPLC with electrochemical detection. PubMed: Ethyl m-digallate from red maple, Acer rubrum L., as the major resistance factor to forest tent caterpillar, Malacosoma disstria Hbn. PubMed: Free radical lipid peroxidation inhibits enzymatic conversion of beta-carotene into vitamin A. PubMed: [Effect of gallic acid derivatives on secretion of Th1 cytokines and Th2 cytokines from anti CD3-stimulated spleen cells]. PubMed: Isolation and characterization of novel benzoates, cinnamates, flavonoids, and lignans from Riesling wine and screening for antioxidant activity. PubMed: [Polyphenol compounds from Hamamelis virginiana L]. PubMed: NMR Analytical Approach To Clarify the Antioxidative Molecular Mechanism of Catechins Using 1,1-Diphenyl-2-picrylhydrazyl. PubMed: NMR analytical approach to clarify the molecular mechanisms of the antioxidative and radical-scavenging activities of antioxidants in tea using 1,1-diphenyl-2-picrylhydrazyl. PubMed: A novel beta-glucuronidase inhibiting triterpenoid from Paeonia emodi. PubMed: Potent and selective inhibition of squalene epoxidase by synthetic galloyl esters. PubMed: The mechanisms underlying the relaxant effect of methyl and ethyl gallates in the guinea pig trachea in vitro: contribution of potassium channels. PubMed: Gallates inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of leukocyte adhesion molecules in vascular endothelial cells. PubMed: Evidence of Trolox and some gallates as synergistic protectors of erythrocytes against peroxyl radicals. PubMed: Modular structures in the mushroom body of the cockroach. PubMed: Extraction and purification of effective antimicrobial constituents of Terminalia chebula RETS. against methicillin-resistant Staphylococcus aureus. PubMed: Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae). PubMed: Morphology of neuroglia in the antennal lobes and mushroom bodies of the brain of the honeybee. PubMed: Neuroanatomy of a crayfish thoracic ganglion: sensory and motor roots of the walking-leg nerves and possible homologies with insects. PubMed: [Chemical constituents of roots of Ampelopsis brevipedunculata (Maxim) Trautv]. PubMed: Cytotoxicity of propyl gallate and related compounds in rat hepatocytes. PubMed: Testing of lipoxygenase inhibitors, cyclooxygenase inhibitors, drugs with immunomodulating properties and some reference antipsoriatic drugs in the modified mouse tail test, an animal model of psoriasis. PubMed: Organization of the commissural fibers in the adult brain of the locust. PubMed: Structural organization of male-specific visual neurons in calliphorid optic lobes. PubMed: Depigmentation and inhibition of cell growth of B-16 melanoma cells by compounds isolated from Paeonia suffruticosa callus. PubMed: The osmium-ethyl gallate procedure is superior to silver impregnations for mapping neuronal pathways. PubMed: The structure of the fourth abdominal ganglion of the crayfish, Procambarus clarki (Girard). I. Tracts in the ganglionic core. PubMed: Identifiable neurons in the locust central nervous system that react with antibodies to serotonin. PubMed: Influence of pH and light on the stability of some antioxidants. PubMed: Lipid staining for the electron microscope: a new method. PubMed: THE USE OF THE OSMIUM-ETHYL GALLATE TECHNIQUE IN THE STUDY OF CARBON TETRACHLORIDE LIVER INJURY. PubMed: Bacteriostatic, bactericidal, and drug resistance studies of ethyl gallate on Mycobacterium tuberculosis. PubMed: Physiological suitability of ethyl gallate as an anti-oxidant. II. The determination of chronic toxicity. PubMed: Physiological suitability of ethyl gallate as an anti-oxidant. I. Acute toxicity dose. PubMed: Ethyl gallate, a mycobacteria-specific antibiotic isolated from Haematoxylon campechianum. II. Microbiological studies. PubMed: Ethyl gallate, a mycobacteria-specific antibiotic isolated from Haematoxylon campechianum. I. Isolation and chemical studies.