ethyl 4-methoxycinnamate
3-(4-methoxyphenyl)-2-propenoic acid ethyl ester
Identification
| Name | ethyl 4-methoxycinnamate |
| IUPAC | ethyl 3-(4-methoxyphenyl)prop-2-enoate |
| CAS Number | 1929-30-2 |
| EINECS | 217-679-6 |
| FDA UNII | Search |
| Molecular Formula | C12 H14 O3 |
| Molecular Weight | 206.24118000 |
| MDL Number | MFCD00026906 |
| XlogP3 | 3.00 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 325.00 to 326.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000235 mmHg @ 25.00 °C. (est) |
| Flash Point | 273.00 °F. TCC ( 133.80 °C. ) (est) |
| logP (o/w) | 3.020 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | uv absorbers |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic UV absorber |
| Recommendation for ethyl 4-methoxycinnamate usage levels up to | not for fragrance use. |
| Recommendation for ethyl 4-methoxycinnamate flavor usage levels up to | not for flavor use. |
BOC Sciences
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O'Laughlin Industries Inc.
Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics
Leading the Flavor and Fragrance Industry since 1980.
Potential Uses
Natural Occurrence
Synonyms
ethyl 3-(4-methoxyphenyl)-2-propenoate
ethyl 3-(4-methoxyphenyl)prop-2-enoate
ethyl methoxycinnamate
ethyl p-methoxycinnamate
ethyl para-methoxycinnamate
4-
methoxy cinnamic acid ethyl ester
4-
methoxycinnamic acid ethyl ester
3-(4-
methoxyphenyl)-2-propenoic acid ethyl ester
PubMed:
Ethyl-p-methoxycinnamate isolated from Kaempferia galanga inhibits inflammation by suppressing interleukin-1, tumor necrosis factor-α, and angiogenesis by blocking endothelial functions.
PubMed:
Moduratory effect of thai traditional medicine (Yahom Tultavai) on hepatic cytochrome P450 enzymes and pentobarbital-induced sleeping in mice.
PubMed:
Hypopigmentary effects of ethyl P-methoxycinnamate isolated from Kaempferia galanga.
PubMed:
Antiangiogenic effects and mechanisms of trans-ethyl p-methoxycinnamate from Kaempferia galanga L.
PubMed:
Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galanga L. extracts.
PubMed:
Ethyl p-methoxycinnamate isolated from a traditional anti-tuberculosis medicinal herb inhibits drug resistant strains of Mycobacterium tuberculosis in vitro.
PubMed:
Supercritical carbon dioxide extraction of ethyl p-methoxycinnamate from Kaempferia galanga L. rhizome and its apoptotic induction in human HepG2 cells.
PubMed:
Chemical composition and larvicidal activity of edible plant-derived essential oils against the pyrethroid-susceptible and -resistant strains of Aedes aegypti (Diptera: Culicidae).
PubMed:
Sedative activity of hexane extract of Keampferia galanga L. and its active compounds.
PubMed:
Larvicidal activity of Kaempferia galanga rhizome phenylpropanoids towards three mosquito species.
PubMed:
[Study on the anti-carcinogenic effects of three compounds in Kaempferia galanga L].
PubMed:
[Studies on the chemical constituents of Securidaca inappendiculata].
PubMed:
[Studies on the chemical constituents of Kaempferia marginata].
PubMed:
Isolation of Ethyl p-methoxycinnamate, the major antifungal principle of Curcumba zedoaria.