dehydrodiisoeugenol
4-(2,3-dihydro-7-methoxy-3-methyl-5-propenyl-2-benzofuranyl)-2-methoxyphenol
Identification
| Name | dehydrodiisoeugenol |
| IUPAC | 2-methoxy-4-[7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol |
| CAS Number | 2680-81-1 |
| FDA UNII | Search |
| Molecular Formula | C20 H22 O4 |
| Molecular Weight | 326.39214000 |
| Nikkaji Number | J1.358.866J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 451.99 °C. @ 760.00 mm Hg (est) |
| Flash Point | 441.00 °F. TCC ( 227.20 °C. ) (est) |
| logP (o/w) | 4.188 (est) |
| Soluble in | water, 0.2551 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for dehydrodiisoeugenol usage levels up to | not for fragrance use. |
| Recommendation for dehydrodiisoeugenol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4-(2,3-
dihydro-7-methoxy-3-methyl-5-propenyl-2-benzofuranyl)-2-methoxyphenol
diisoeugenol, dehydro-
iso
eugenol, dehydrodi-
2-
methoxy-4-[7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol
phenol, 4-(2,3-dihydro-7-methoxy-3-methyl-5-propenyl-2-benzofuranyl)-2-methoxy- (8CI)
phenol, 4-[2,3-dihydro-7-methoxy-3-methyl-5-(1-propenyl)-2-benzofuranyl]-2-methoxy-
PubMed:
New inhibitors of nitric oxide production from the seeds of Myristica fragrans.
PubMed:
Cerebral nuclei distribution study of dehydrodiisoeugenol as an anxiogenic agent determined by RP-HPLC.
PubMed:
Analysis of anti-inflammatory dehydrodiisoeugenol and metabolites excreted in rat feces and urine using HPLC-UV.
PubMed:
Enantiomeric resolution of (±)-licarin A by high-performance liquid-chromatography using a chiral stationary phase.
PubMed:
Metabolism of the lignan dehydrodiisoeugenol in rats.
PubMed:
Cytotoxic and anti-infective phenolic compounds isolated from Mikania decora and Cremastosperma microcarpum.
PubMed:
[Studies on the chemical constituents of Litsea lancifolia].
PubMed:
Determination of dehydrodiisoeugenol in rat tissues using HPLC method.
PubMed:
[New neolignan from seed of Myristica fragrans].
PubMed:
Skin sensitization potency of isoeugenol and its dimers evaluated by a non-radioisotopic modification of the local lymph node assay and guinea pig maximization test.
PubMed:
Biotransformation of isoeugenol to vanillin by a newly isolated Bacillus pumilus strain: identification of major metabolites.
PubMed:
Predicting the biological activities of 2-methoxyphenol antioxidants: effects of dimers.
PubMed:
Metabolism of isoeugenol via isoeugenol-diol by a newly isolated strain of Bacillus subtilis HS8.
PubMed:
Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds.
PubMed:
Dehydrodiisoeugenol, an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages.
PubMed:
Cytotoxicity and radical intensity of eugenol, isoeugenol or related dimers.
PubMed:
Simple synthesis of benzofuranoid neolignans from Myristica fragrans.
PubMed:
The biomimetic oxidation of beta-1, beta-0-4, beta-5, and biphenyl lignin model compounds by synthetic iron porphyrins.
PubMed:
Isolation and characterization of an anaerobic dehydrodivanillin-degrading bacterium.
PubMed:
Antitumor plants. X. Constituents of Nectandra rigida.
PubMed:
Dehydrodiisoeugenol: a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae).