methyl furoate

3-furancarboxylic acid, methyl ester

CAS: 1334-76-5 C6 H6 O3 MW: 126.11142000 berry

Identification

Namemethyl furoate
IUPACmethyl furan-3-carboxylate
CAS Number1334-76-5
EINECS215-614-6
FDA UNIIWS10TS94NA
Molecular FormulaC6 H6 O3
Molecular Weight126.11142000
MDL NumberMFCD06203671
Nikkaji NumberJ127.896G
XlogP31.30 (est)

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 154.00 to 155.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 2.436000 mmHg @ 25.00 °C. (est)
Flash Point 117.00 °F. TCC ( 47.30 °C. ) (est)
logP (o/w) 1.297 (est)
Soluble in alcohol

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for methyl furoate usage levels up tonot for fragrance use.
Recommendation for methyl furoate flavor usage levels up tonot for flavor use.

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Potential Uses

FR fungus

Natural Occurrence

coffee roasted coffee PMC kiwi fruit malpighia glabra fruit oil @ 0.10% Data soursop star fruit oil cuba @ trace% Data wine cabernet sauvignon wine

Synonyms

furan carboxylic acid methyl ester furancarboxylic acid methyl ester 3- furancarboxylic acid methyl ester 3- furancarboxylic acid, methyl ester 3- furancarboxylicacidmethylester furoic acid methyl ester furoic acid, methyl ester 3- furoic acid, methyl ester methyl 3-furancarboxylate methyl 3-furoate methyl furan carboxylate methyl furan-3-carboxylate PubMed: Mometasone furoate-loaded cold processed oil-in-water emulsions: in vitro and in vivo studies. PubMed: Asymmetric synthesis of both enantiomers of arteludovicinolide A. PubMed: An efficient method for the determination of furan derivatives in apple cider and wine by solid phase extraction and high performance liquid chromatography--diode array detector. PubMed: 1H NMR spectra. Part 29§: Proton chemical shifts and couplings in esters--the conformational analysis of methyl γ-butyrolactones. PubMed: Efficacy and safety of 15(R/S)-methyl-lipoxin A(4) in topical treatment of infantile eczema. PubMed: Chemical and biochemical study of industrially produced San Simón da Costa smoked semi-hard cow's milk cheeses: Effects of storage under vacuum and different modified atmospheres. PubMed: Gateways to clinical trials. PubMed: Gateways to clinical trials. PubMed: Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases. PubMed: Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure. PubMed: Pentane-1,5-diol as a percutaneous absorption enhancer. PubMed: Stability indicating reversed-phase liquid chromatographic determination of metronidazole benzoate and diloxanide furoate as bulk drug and in suspension dosage form. PubMed: A ceramic electrochemical microreactor for the methoxylation of methyl-2-furoate with direct mass spectrometry coupling. PubMed: Enzymatic hydrolysis of diloxanide furoate in the presence of beta-cyclodextrin and its methylated derivatives. PubMed: Mometasone furoate degradation and metabolism in human biological fluids and tissues. PubMed: Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide. PubMed: Generation of Maillard compounds from inulin during the thermal processing of Agave tequilana Weber Var. azul. PubMed: Phenolic compounds from tournefortia sarmentosa PubMed: The therapeutic efficacy of mometasone furoate cream 0.1% applied once daily vs clobetasol propionate cream 0.05% applied twice daily in chronic eczema. PubMed: Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. PubMed: Metabolic reduction of novel 3,4-dichloro-5-nitrofurans in Salmonella typhimurium. PubMed: Mutagenicity of N- and O-acetyl derivatives of methyl 3,4-diphenyl-5-hydroxylamino-2-furoate and N-hydroxy-4-aminobiphenyl in Salmonella typhimurium. PubMed: Cytokine inhibition by a novel steroid, mometasone furoate. PubMed: Platelet activating factor antagonist design. 3. X-ray crystal structure and intermolecular crystal lattice interactions of methyl trans-4-acetoxymethyl-4,5-dihydro-2,5-bis(3,4-methylenedioxyphenyl)- 3-furancarboxylate. PubMed: Platelet activating factor antagonist design: structure of methyl trans-5-(3,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-2-oxo-4- furancarboxylate. PubMed: 17-Heteroaroyl esters of corticosteroids. 2. 11 beta-Hydroxy series. PubMed: Synthesis and structure-activity studies of corticosteroid 17-heterocyclic aromatic esters. 1. 9 alpha, 11 beta-dichloro series. PubMed: Mutagenicity of 3,4-diphenyl-5-nitrofuran analogs in Salmonella typhimurium. PubMed: Formation of novel nitrofuran metabolites in xanthine oxidase-catalyzed reduction of methyl 5-nitro-2-furoate. PubMed: Reduction of methyl 5-nitro-2-furoate by xanthine oxidase: an evidence for hydroxylaminofuran formation. PubMed: Synthesis and local anesthetic activity of benzo[b]furan derivatives.