methyl furoate
3-furancarboxylic acid, methyl ester
Identification
| Name | methyl furoate |
| IUPAC | methyl furan-3-carboxylate |
| CAS Number | 1334-76-5 |
| EINECS | 215-614-6 |
| FDA UNII | WS10TS94NA |
| Molecular Formula | C6 H6 O3 |
| Molecular Weight | 126.11142000 |
| MDL Number | MFCD06203671 |
| Nikkaji Number | J127.896G |
| XlogP3 | 1.30 (est) |
Regulatory
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 154.00 to 155.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 2.436000 mmHg @ 25.00 °C. (est) |
| Flash Point | 117.00 °F. TCC ( 47.30 °C. ) (est) |
| logP (o/w) | 1.297 (est) |
| Soluble in | alcohol |
Organoleptic Properties
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for methyl furoate usage levels up to | not for fragrance use. |
| Recommendation for methyl furoate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
furan carboxylic acid methyl ester
furancarboxylic acid methyl ester
3-
furancarboxylic acid methyl ester
3-
furancarboxylic acid, methyl ester
3-
furancarboxylicacidmethylester
furoic acid methyl ester
furoic acid, methyl ester
3-
furoic acid, methyl ester
methyl 3-furancarboxylate
methyl 3-furoate
methyl furan carboxylate
methyl furan-3-carboxylate
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Asymmetric synthesis of both enantiomers of arteludovicinolide A.
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An efficient method for the determination of furan derivatives in apple cider and wine by solid phase extraction and high performance liquid chromatography--diode array detector.
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1H NMR spectra. Part 29§: Proton chemical shifts and couplings in esters--the conformational analysis of methyl γ-butyrolactones.
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Gateways to clinical trials.
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Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases.
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Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure.
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Stability indicating reversed-phase liquid chromatographic determination of metronidazole benzoate and diloxanide furoate as bulk drug and in suspension dosage form.
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A ceramic electrochemical microreactor for the methoxylation of methyl-2-furoate with direct mass spectrometry coupling.
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Enzymatic hydrolysis of diloxanide furoate in the presence of beta-cyclodextrin and its methylated derivatives.
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Metabolic reduction of novel 3,4-dichloro-5-nitrofurans in Salmonella typhimurium.
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Mutagenicity of N- and O-acetyl derivatives of methyl 3,4-diphenyl-5-hydroxylamino-2-furoate and N-hydroxy-4-aminobiphenyl in Salmonella typhimurium.
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Cytokine inhibition by a novel steroid, mometasone furoate.
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Platelet activating factor antagonist design. 3. X-ray crystal structure and intermolecular crystal lattice interactions of methyl trans-4-acetoxymethyl-4,5-dihydro-2,5-bis(3,4-methylenedioxyphenyl)- 3-furancarboxylate.
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Platelet activating factor antagonist design: structure of methyl trans-5-(3,4-dimethoxyphenyl)-2,3,4,5-tetrahydro-2-oxo-4- furancarboxylate.
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Mutagenicity of 3,4-diphenyl-5-nitrofuran analogs in Salmonella typhimurium.
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Formation of novel nitrofuran metabolites in xanthine oxidase-catalyzed reduction of methyl 5-nitro-2-furoate.
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Reduction of methyl 5-nitro-2-furoate by xanthine oxidase: an evidence for hydroxylaminofuran formation.
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Synthesis and local anesthetic activity of benzo[b]furan derivatives.