panaxytriol

1-heptadecene-4,6-diyne-3,9,10-triol

CAS: 87005-03-6 C17 H26 O3 MW: 278.39182000

Identification

Namepanaxytriol
IUPACheptadec-1-en-4,6-diyne-3,9,10-triol
CAS Number87005-03-6
FDA UNIISearch
Molecular FormulaC17 H26 O3
Molecular Weight278.39182000
Nikkaji NumberJ38.610C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 474.81 °C. @ 760.00 mm Hg (est)
Flash Point 426.00 °F. TCC ( 219.00 °C. ) (est)
logP (o/w) 4.218 (est)
Soluble in water, 18.61 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for panaxytriol usage levels up tonot for fragrance use.
Recommendation for panaxytriol flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Potential Uses

None Found

Natural Occurrence

ginseng

Synonyms

heptadec-1-en-4,6-diyne-3,9,10-triol 1- heptadecene-4,6-diyne-3,9,10-triol PubMed: Network pharmacology analyses of the antithrombotic pharmacological mechanism of Fufang Xueshuantong Capsule with experimental support using disseminated intravascular coagulation rats. PubMed: Direct and comprehensive analysis of ginsenosides and diterpene alkaloids in Shenfu injection by combinatory liquid chromatography-mass spectrometric techniques. PubMed: [Chemical constituents from stems of Cistanche deserticola cultured in Tarim desert]. PubMed: Identification of the active components in Shenmai injection that differentially affect Cyp3a4-mediated 1'-hydroxylation and 4-hydroxylation of midazolam. PubMed: Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol. PubMed: (3R, 9R, 10R)-Panaxytriol: A molecular-based nutraceutical with possible application to cancer prevention and treatment. PubMed: Induction of chemoprotective phase 2 enzymes by ginseng and its components. PubMed: Imaging induction of cytoprotective enzymes in intact human cells: coumberone, a metabolic reporter for human AKR1C enzymes reveals activation by panaxytriol, an active component of red ginseng. PubMed: Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro. PubMed: Total synthesis of (3R,9R,10R)-panaxytriol via tandem metathesis and metallotropic [1,3]-shift as a key step. PubMed: Total synthesis as a resource in drug discovery: the first in vivo evaluation of panaxytriol and its derivatives. PubMed: Straightforward synthesis of panaxytriol: an active component of Red Ginseng. PubMed: Chemoenzymatic asymmetric total syntheses of antitumor agents (3R,9R,10R)- and (3S,9R,10R)-Panaxytriol and (R)- and (S)-Falcarinol from Panax ginseng using an enantioconvergent enzyme-triggered cascade reaction. PubMed: Gymnasterkoreaynes A-F, cytotoxic polyacetylenes from Gymnaster koraiensis. PubMed: Inhibitory effect of tumor cell proliferation and induction of G2/M cell cycle arrest by panaxytriol. PubMed: Absolute structure of panaxytriol. PubMed: In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng. PubMed: Inducible nitric oxide synthase inhibitors from Saposhnikovia divaricata and Panax quinquefolium. PubMed: Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. PubMed: Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase. PubMed: [Polyacetylene compounds from Panax notoginsenoside]. PubMed: Screening of polyacetylenic alcohols in crude drugs using the ELISA for panaxytriol. PubMed: A possible mechanism for the cytotoxicity of a polyacetylenic alcohol, panaxytriol: inhibition of mitochondrial respiration. PubMed: A highly sensitive enzyme-linked immunosorbent assay (ELISA) for antitumor polyacetylenic alcohol, panaxytriol. PubMed: Potentiation of cytotoxicity of mitomycin C by a polyacetylenic alcohol, panaxytriol. PubMed: The first specific antibody against cytotoxic polyacetylenic alcohol, panaxynol. PubMed: [Thin layer chromatography and extractive technology of Panax japonicum C.A. Mey. var. major (Burk.) C. Y. Wu et K. M. Feng growing in Qingba Mountain Area]. PubMed: Cytotoxic activity of polyacetylene compounds in Panax ginseng C. A. Meyer. PubMed: [Cell growth inhibitory substance isolated from Panax ginseng root: panaxytriol]. PubMed: Determination of panaxytriol, a new type of tumour growth inhibitor from Panax ginseng, by capillary gas chromatography. PubMed: Studies on the panaxytriol of Panax ginseng C. A. Meyer. Isolation, determination and antitumor activity. PubMed: [A tumor inhibitory substance from panax ginseng].