cafestol palmitate
(5-oxofuran-2(5H)-ylidene)acetic acid
Identification
| Name | cafestol palmitate |
| CAS Number | 81760-46-5 |
| FDA UNII | P8W9M3T86Y |
| Molecular Formula | C36 H58 O4 |
| Molecular Weight | 554.85506000 |
| MDL Number | MFCD01075770 |
| Beilstein | 003111 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 629.00 to 630.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 305.00 °F. TCC ( 151.40 °C. ) (est) |
| logP (o/w) | 0.311 (est) |
| Soluble in | water, 6.884e-008 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cafestol palmitate usage levels up to | not for fragrance use. |
| Recommendation for cafestol palmitate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
acetic acid, 2-(5-oxo-2(5H)-furanylidene)-, (2E)-
cafestol palmitate
(5-oxo
furan-2(5H)-ylidene)acetic acid
(2E)-(5-oxo
furan-2(5H)-ylidene)ethanoic acid
PubMed:
Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
PubMed:
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
PubMed:
Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase.
PubMed:
Use of silver nitrate impregnated silica cartridges in the separation of kahweol and cafestol esters by preparative liquid chromatography.
PubMed:
Inhibition of carcinogenesis by some minor dietary constituents.
PubMed:
Inhibition of neoplasia by minor dietary constituents.
PubMed:
Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse.