phytanic acid
hexadecanoic acid, 3,7,11,15-tetramethyl- (8CI)(9CI)
Identification
| Name | phytanic acid |
| IUPAC | 3,7,11,15-tetramethylhexadecanoic acid |
| CAS Number | 14721-66-5 |
| FDA UNII | 8OYE5TF5VL |
| Molecular Formula | C20 H40 O2 |
| Molecular Weight | 312.53720000 |
| MDL Number | MFCD00133772 |
| Nikkaji Number | J14.320K |
| Beilstein | 1789963 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.001092 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for phytanic acid usage levels up to | not for fragrance use. |
| Recommendation for phytanic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
hexadecanoic acid, 3,7,11,15-tetramethyl- (8CI)(9CI)
3,7,11,15-
tetramethyl hexadecanoic acid
3,7,11,15-
tetramethylhexadecanoic acid
PubMed:
Dietary influences on tissue concentrations of phytanic acid and AMACR expression in the benign human prostate.
PubMed:
Lipocalin 2 expression and secretion is highly regulated by metabolic stress, cytokines, and nutrients in adipocytes.
PubMed:
Novel aspects of health promoting compounds in meat.
PubMed:
Toxicological issues associated with production and processing of meat.
PubMed:
Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes.
PubMed:
Plasma fatty acids in premature infants with hyperbilirubinemia: before-and-after nutrition support with fish oil emulsion.
PubMed:
Characterization of two Agrostis-Festuca alpine pastures and their influence on cheese composition.
PubMed:
Content and distribution of phytanic acid diastereomers in organic milk as affected by feed composition.
PubMed:
Phytanic acid and the risk of non-Hodgkin lymphoma.
PubMed:
Estimated phytanic acid intake and prostate cancer risk: a prospective cohort study.
PubMed:
AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk.
PubMed:
Phytanic acid--an overlooked bioactive fatty acid in dairy fat?
PubMed:
Identification of marker genes for lipid-lowering effect of a short-chain fructooligosaccharide by DNA microarray analysis.
PubMed:
Correlations of dietary patterns with prostate health.
PubMed:
Phytanic acid: measurement of plasma concentrations by gas-liquid chromatography-mass spectrometry analysis and associations with diet and other plasma fatty acids.
PubMed:
Polyunsaturated fats attenuate the dietary phytol-induced increase in hepatic fatty acid oxidation in mice.
PubMed:
Serum levels of phytanic acid are associated with prostate cancer risk.
PubMed:
Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.
PubMed:
Serum levels of phytanic acid are associated with prostate cancer risk.
PubMed:
Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands.
PubMed:
Nutraceutical resources for diabetes prevention--an update.
PubMed:
Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells.
PubMed:
Nutrition and retinal degenerations.
PubMed:
The design of a diet restricted in saturated very long-chain fatty acids: therapeutic application in adrenoleukodystrophy.
PubMed:
The influence of dietary branched-chain fatty acids on the fatty acid composition of tissue- lipids of rats.
PubMed:
Heredopathia atactica polyneuritiformis (Refsum's disease): 2. Estimation of phytanic acid in foods.
PubMed:
Naturally occurring food toxicants: toxic lipids.