2,4-hexadienal

hexa-2,4-dienal

CAS: 80466-34-8 C6 H8 O MW: 96.12896000 green green

Identification

Name2,4-hexadienal
CAS Number80466-34-8
FDA UNIISearch
Molecular FormulaC6 H8 O
Molecular Weight96.12896000

Regulatory

Physical Properties

Appearance pale yellow to yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 155.86 °C. @ 760.00 mm Hg (est)
Vapor Pressure 2.970000 mmHg @ 25.00 °C. (est)
Flash Point 143.00 °F. TCC ( 61.70 °C. ) (est)
logP (o/w) 1.381 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Strength high ,
Substantivity > 1 hour(s) at 100.00 %
Odor Description
at 1.00 % in dipropylene glycol.
Fatty, sweet, green aldehydic odor with a spicy finish
Taste Description
green creamy
Sweet, green, creamy

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
IFRA Critical EffectInsufficient data
Recommendation for 2,4-hexadienal usage levels up toPROHIBITED: Should not be used as a fragrance ingredient.

Bedoukian Research, Inc.

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CJ Latta & Associates, LLC

Extensive Line

Aromatic Chemicals and Organic Acids.

View All Website (630) 240-8079 chiplatta@msn.com

Potential Uses

None Found

Natural Occurrence

caraway seed cascarilla bark oil @ trace% Data corn silk

Synonyms

hexa-2,4-dienal 2,4- hexadien-1-al PubMed: Comprehensive analysis of the catalytic and structural properties of a mu-class glutathione s-transferase from Fasciola gigantica. PubMed: Degradation of Diphenyl Ether in Sphingobium phenoxybenzoativorans SC_3 Is Initiated by a Novel Ring Cleavage Dioxygenase. PubMed: Multi-trait analysis of post-harvest storage in rocket salad (Diplotaxis tenuifolia) links sensorial, volatile and nutritional data. PubMed: PARTICIPATION OF Y89 AND Y97 IN THE CONJUGATING ACTIVITY OF Drosophila melanogaster GLUTATHIONE S-TRANSFERASE D3 (DmGSTD3). PubMed: Use of TD-GC-TOF-MS to assess volatile composition during post-harvest storage in seven accessions of rocket salad (Eruca sativa). PubMed: Change of volatile compounds in fresh fish meat during ice storage. PubMed: exo-Selective asymmetric Diels-Alder reaction of 2,4-dienals and nitroalkenes by trienamine catalysis. PubMed: Laboratory investigation on the role of organics in atmospheric nanoparticle growth. PubMed: Volatile composition of four southern highbush blueberry cultivars and effect of growing location and harvest date. PubMed: Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds. PubMed: Synthesis and biological evaluation of (+/-)-dinemasone C and analogues. PubMed: The fate of benzene-oxide. PubMed: Aldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived alpha, beta-unsaturated carbonyls at physiological levels. PubMed: Effect of soybean volatile compounds on Aspergillus flavus growth and aflatoxin production. PubMed: A kinetic and mechanistic study of the amino acid catalyzed aldol condensation of acetaldehyde in aqueous and salt solutions. PubMed: Characterization of Taenia solium cysticerci microsomal glutathione S-transferase activity. PubMed: The atmospheric photolysis of E-2-hexenal, Z-3-hexenal and E,E-2,4-hexadienal. PubMed: Volatile emissions from Aesculus hippocastanum induced by mining of larval stages of Cameraria ohridella influence oviposition by conspecific females. PubMed: Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4. PubMed: Syntheses of (-)-TAN-2483A, (-)-massarilactone B, and the fusidilactone B ring system. Revision of the structures of and syntheses of (+/-)-Waol A (FD-211) and (+/-)-Waol B (FD-212). PubMed: Purification, characterization and kinetic properties of the Taenia solium glutathione S-transferase isoform 26.5 kDa. PubMed: NTP toxicology and carcinogensis Studies of 2,4-hexadienal (89% trans,trans isomer, CAS No. 142-83-6; 11% cis,trans isomer) (Gavage Studies). PubMed: Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities. PubMed: Particle growth by acid-catalyzed heterogeneous reactions of organic carbonyls on preexisting aerosols. PubMed: Alpha,beta-unsaturated carbonyl compounds: induction of oxidative DNA damage in mammalian cells. PubMed: Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice. PubMed: Synthesis of (-)-TAN-2483A. Revision of the structures and syntheses of (+/-)-FD-211 (waol A) and (+/-)-FD-212 (waol B). PubMed: Short term feeding of hexadienal to postnatal rats: effects on stomach aldehyde dehydrogenase. PubMed: Thresholds of carcinogenicity of flavors. PubMed: Identification of aroma compounds in Parmigiano-Reggiano cheese by gas chromatography/olfactometry. PubMed: The influence of the solvents DMSO and ethanol on the genotoxicity of alpha,beta-unsaturated aldehydes in the SOS chromotest. PubMed: Glutathione S-transferase pi expression in forestomach carcinogenesis process induced by gavage-administered 2,4-hexadienal in the F344 rat. PubMed: DNA-damaging potential and glutathione depletion of 2-cyclohexene-1-one in mammalian cells, compared to food relevant 2-alkenals. PubMed: Structure-activity relationships in the induction of DNA-protein cross-links by hematotoxic ring-opened benzene metabolites and related compounds in HL60 cells. PubMed: Appearance of cross linked proteins in human atheroma and rat pre-fibrotic liver detected by a new monoclonal antibody. PubMed: Reactive ring-opened aldehyde metabolites in benzene hematotoxicity. PubMed: Neighboring Group Effects in Intramolecular Aldol Condensations. Rate Enhancement by gamma Substituents(1). PubMed: Chemistry and antimicrobial activity of caryoynencins analogs. PubMed: Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite. PubMed: The hematotoxic effects of 6-hydroxy-trans,trans-2,4-hexadienal, a reactive metabolite of trans,trans-muconaldehyde, in CD-1 mice. PubMed: Interaction of trans,trans-muconaldehyde with bovine serum albumin. PubMed: Mutagenicity of trans,trans-muconaldehyde and its metabolites in V79 cells. PubMed: Reaction of (E,E)-muconaldehyde and its aldehydic metabolites, (E,E)-6-oxohexadienoic acid and (E,E)-6-hydroxyhexa-2,4-dienal, with glutathione. PubMed: Identification and characterization of deoxyguanosine adducts of mutagenic beta-alkyl-substituted acrolein congeners. PubMed: Pathways of trans,trans-muconaldehyde metabolism in mouse liver cytosol: reversibility of monoreductive metabolism and formation of end products. PubMed: Cell spreading on collagen that has been exposed to reactive aldehydes. PubMed: Mutagenicity of beta-alkyl substituted acrolein congeners in the Salmonella typhimurium strain TA100 and genotoxicity testing in the SOS chromotest. PubMed: Pseudo malonaldehyde activity in the thiobarbituric acid test.