ubiquinone-5
2,5-cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(3,7,11,15,19-pentamethyl-2,6,10,14,18-eicosapentaenyl)-, (all-E)-
Identification
| Name | ubiquinone-5 |
| IUPAC | 2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E)-3,7,11,15,19-pentamethylicosa-2,6,10,14,18-pentaenyl]cyclohexa-2,5-diene-1,4-dione |
| CAS Number | 4370-61-0 |
| FDA UNII | Search |
| Molecular Formula | C34 H50 O4 |
| Molecular Weight | 522.76930000 |
| MDL Number | MFCD00274412 |
| Nikkaji Number | J492.361H |
| Beilstein | 2315703 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 3.411e-008 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ubiquinone-5 usage levels up to | not for fragrance use. |
| Recommendation for ubiquinone-5 flavor usage levels up to | not for flavor use. |
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
Potential Uses
Natural Occurrence
Synonyms
coenzyme Q5
2,5-
cyclohexadiene-1,4-dione, 2,3-dimethoxy-5-methyl-6-(3,7,11,15,19-pentamethyl-2,6,10,14,18-eicosapentaenyl)-, (all-E)-
(all-E)-2,3-
dimethoxy-5-methyl-6-(3,7,11,15,19-pentamethyl-2,6,10,14,18-eicosapentaenyl)-2,5-cyclohexadiene-1,4-dione
2,3-
dimethoxy-5-methyl-6-[(2E,6E,10E,14E)-3,7,11,15,19-pentamethylicosa-2,6,10,14,18-pentaenyl]cyclohexa-2,5-diene-1,4-dione
ubiquinone 25
ubiquinone 5
PubMed:
Effects of ubiquinone derivatives on the mitochondrial unselective channel of Saccharomyces cerevisiae.
PubMed:
Prerequisites for ubiquinone analogs to prevent mitochondrial permeability transition-induced cell death.
PubMed:
Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death.
PubMed:
Coenzyme Q(1) depletes NAD(P)H and impairs recycling of ascorbate in astrocytes.
PubMed:
Hepatocyte metabolism of coenzyme Q1 (ubiquinone-5) to its sulfate conjugate decreases its antioxidant activity.
PubMed:
Electrochemical properties of natural organic matter (NOM), fractions of NOM, and model biogeochemical electron shuttles.
PubMed:
Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site.
PubMed:
A ubiquinone-binding site regulates the mitochondrial permeability transition pore.
PubMed:
Partial Purification and Characterization of Complex I, NADH:Ubiquinone Reductase, from the Inner Membrane of Beetroot Mitochondria.
PubMed:
Ubiquinone-5 is reduced by superoxide in the aerobic state by NADPH oxidase of guinea pig macrophages.
PubMed:
The inhibition of plant mitochondrial respiration by the synthetic analog of ubiquinone, 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT).
PubMed:
Characterization of purified cytochrome b-c1 complex from Rhodopseudomonas sphaeroides R-26.
PubMed:
On the role of ubiquinone in the respiratory chain.
PubMed:
Partial purification and properties of respiratory chain-linked l-glycerol 3-phosphate dehydrogenase from a marine bacterium, Vibrio alginolyticus.
PubMed:
Inhibition of electron transfer in the cytochrome b-c, segment of the mitochondrial respiratory chain by a synthetic analogue of ubiquinone.
PubMed:
Bioenergetics in clinical medicine: prevention by forms of coenzyme Q of the inhibition by adriamycin of coenzyme Q10-enzymes in mitochondria of the myocardium.
PubMed:
Effect of alpha-p-chlorophenoxyisobutyrate on the metabolism of isoprenoid compounds in the rat.
PubMed:
Isolation of ubiquinone-5, new member of ubiquinone group.