shikimin
anisatin
Identification
| Name | shikimin |
| CAS Number | 51372-90-8 |
| FDA UNII | Search |
| Molecular Formula | C15 H20 O8 |
| Molecular Weight | 328.31800000 |
| Nikkaji Number | J3.036.272A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 609.49 °C. @ 760.00 mm Hg (est) |
| Flash Point | 446.00 °F. TCC ( 230.10 °C. ) (est) |
| logP (o/w) | -1.894 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for shikimin usage levels up to | not for fragrance use. |
| Recommendation for shikimin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
anisatin
hexahydro-1,5,6a,7-tetrahydroxy-5,9-dimethyl spiro(6H-4,9a-methanocyclopent(d)oxocin-6,3'-oxetane)-2,2'(1H)-dione
spiro(6H-4,9a-methanocyclopent(d)oxocin-6,3'-oxetane)-2,2'(1H)-dione, hexahydro-1,5,6a,7-tetrahydroxy-5,9-dimethyl-
PubMed:
A bird's eye view of anisatin induced convulsive seizures in brain by a (1)H NMR based metabolic approach.
PubMed:
Rapid and simple neurotoxin-based distinction of Chinese and Japanese star anise by direct plant spray mass spectrometry.
PubMed:
Analysis of the neurotoxin anisatin in star anise by LC-MS/MS.
PubMed:
A new phenylpropanoid glycoside from the fruits of Illicium simonsii.
PubMed:
Rapid control of Chinese star anise fruits and teas for neurotoxic anisatin by Direct Analysis in Real Time high resolution mass spectrometry.
PubMed:
A case of infantile star anise toxicity.
PubMed:
Total synthesis of (-)-anisatin.
PubMed:
[Apparent life-threatening event in infants: think about star anise intoxication!].
PubMed:
[Two new sesquiterpene lactones from the pericarp of Illicium macranthum].
PubMed:
Henrylactones A-E and anti-HBV constituents from Illicium henryi.
PubMed:
Combination of TLC and HPLC-MS/MS methods. Approach to a rational quality control of Chinese star anise.
PubMed:
Molecular mechanisms of toxicity of important food-borne phytotoxins.
PubMed:
Tea: not immoral, illegal, or fattening, but is it innocuous?
PubMed:
[An epidemic of epileptic seizures after consumption of herbal tea].
PubMed:
Structure-activity relationships of seco-prezizaane terpenoids in gamma-aminobutyric acid receptors of houseflies and rats.
PubMed:
Synthetic studies toward anisatin: a formal synthesis of (+/-)-8-deoxyanisatin.
PubMed:
The molecular structure of 2alpha-hydroxyneoanisatin and structure-activity relationships among convulsant sesquiterpenes of the seco-prezizaane and picrotoxane types.
PubMed:
Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons.
PubMed:
[Plant toxicity-coriamyrtin, anisatin, cicutoxin].
PubMed:
Interaction of anisatin with rat brain gamma-aminobutyric acidA receptors: allosteric modulation by competitive antagonists.
PubMed:
New Sesquiterpene Lactones from Illicium floridanum
PubMed:
Neurotropic components from star anise (Illicium verum Hook. fil.)
PubMed:
[Studies on the toxic constituents of Illicium simonsii Maxim].
PubMed:
[The toxic principle of Illicium henryi Diels and structure of 6-deoxypseudoanisatin].
PubMed:
Pharmacology of GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria).
PubMed:
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
PubMed:
Neuropharmacological studies on the receptors mediating responses to carbachol, amino acids and octopamine on Limulus and Hirudo central neurons.
PubMed:
Anisatin modulation of temperature-dependent inhibition [3H]muscimol binding by chloride ion.
PubMed:
Anisatin modulation of GABA- and pentobarbital-induced enhancement of diazepam binding in rat brain.
PubMed:
Effects of anisatin on the GABA action in the crayfish neuromuscular junction.
PubMed:
Anisatin, a potent GABA antagonist, isolated from Illicium anisatum.
PubMed:
Central actions of shikimin and tutin.