5-hydroxypentanoic acid
valeric acid, 5-hydroxy-
Identification
| Name | 5-hydroxypentanoic acid |
| CAS Number | 13392-69-3 |
| FDA UNII | H5EVV4LP59 |
| Molecular Formula | C5 H10 O3 |
| Molecular Weight | 118.13230000 |
| Nikkaji Number | J140.264A |
| XlogP3 | -0.10 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 268.20 °C. @ 760.00 mm Hg (est) |
| Flash Point | 267.00 °F. TCC ( 130.30 °C. ) (est) |
| logP (o/w) | -0.390 (est) |
| Soluble in | water, 6.792e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for 5-hydroxypentanoic acid usage levels up to | not for fragrance use. |
| Recommendation for 5-hydroxypentanoic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
delta-
hydroxypentanoic acid
5-
hydroxyvaleric acid
pentanoic acid, 5-hydroxy-
valeric acid, 5-hydroxy-
PubMed:
Drought stress increases the production of 5-hydroxynorvaline in two C4 grasses.
PubMed:
Effect of heat treatment on the antioxidant activity of extracts from citrus peels.
PubMed:
Pregnane- and furostane-type oligoglycosides from the seeds of Allium tuberosum.
PubMed:
A tertiary alcohol analog of gamma-hydroxybutyric acid as a specific gamma-hydroxybutyric acid receptor ligand.
PubMed:
Anti-arthritic effects of the novel dipeptidyl peptidase IV inhibitors TMC-2A and TSL-225.
PubMed:
Unusual dehydrations in anaerobic bacteria: considering ketyls (radical anions) as reactive intermediates in enzymatic reactions.
PubMed:
Determination of valproic acid and its metabolites using gas chromatography with mass-selective detection: application to serum and urine samples from sheep.
PubMed:
The identification of 5-hydroxy-L-norvaline in cultures of pyridoxine auxotrophs of Escherichia coli B.
PubMed:
Studies on the renal transport of trimethylpentanoic acid metabolites of 2,2,4-trimethylpentane in rat renal cortical slices.
PubMed:
Mechanism of action of an antifungal antibiotic, RI-331, (S) 2-amino-4-oxo-5-hydroxypentanoic acid; kinetics of inactivation of homoserine dehydrogenase from Saccharomyces cerevisiae.
PubMed:
The mechanism of antifungal action of (S)-2-amino-4-oxo-5-hydroxypentanoic acid, RI-331: the inhibition of homoserine dehydrogenase in Saccharomyces cerevisiae.
PubMed:
The mode of antifungal action of (S)2-amino-4-oxo-5-hydroxypentanoic acid, RI-331.
PubMed:
Nucleoside phosphotransferase from malt sprouts. II. Studies on the active site and the phospho-intermediate.
PubMed:
Direct chemical evidence for the mixed anhydride intermediate of carboxypeptidase A in ester and peptide hydrolysis.
PubMed:
Mechanism of action of butyryl-CoA dehydrogenase: reactions with acetylenic, olefinic, and fluorinated substrate analogues.
PubMed:
Metabolism of branched medium chain length fatty acid. II--beta-oxidation of sodium dipropylacetate in rats.