Identification

Namedipropyl trisulfide
IUPAC1-propylsulfanyldisulfanylpropane
CAS Number6028-61-1
EINECS227-903-4
FDA UNIIU4529NM2C1
Molecular FormulaC6 H14 S3
Molecular Weight182.37258000
Nikkaji NumberJ99.403K
Beilstein1736293
CoE Number726

Regulatory

JECFA Food Flavoring585 dipropyl trisulfide
DG SANTE Food Flavourings12.023 dipropyl trisulfide
FEMA Number3276
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)6028-61-1 ; DIPROPYL TRISULFIDE

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 99.00 to 100.00 sum of isomers
Food Chemicals Codex Listed No
Specific Gravity 0.95200 @ 25.00 °C.
Refractive Index 1.54200 to 1.59000 @ 20.00 °C.
Boiling Point 86.00 to 89.00 °C. @ 1.50 mm Hg, 98.00 °C. @ 4.00 mm Hg
Vapor Pressure 0.024000 mmHg @ 25.00 °C. (est)
Vapor Density 6.2 ( Air = 1 )
Flash Point 167.00 °F. TCC ( 75.00 °C. )
logP (o/w) 3.964 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description
at 0.10 % in propylene glycol.
Sulfureous, alliaceous, pungent, green and onion-like with slight tropical and vegetative nuances
sweet/herbaceous, garlic-like
Taste Description
at 2.00 ppm.
garlic

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-mouse LD50 [sex: M,F] 800 - 1600 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for dipropyl trisulfide usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)11.28 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)1.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)348 (μg/person/day)
NOEL (No Observed Effect Level)4.8 (mg/kg bw per day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)0.60000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)0.04000
Edible ices, including sherbet and sorbet (03.0)0.50000
Processed fruit (04.1)-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)0.20000
Confectionery (05.0)0.75000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)0.62000
Bakery wares (07.0)0.80000
Meat and meat products, including poultry and game (08.0)0.73000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)0.10000
Eggs and egg products (10.0)0.08000
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)0.45000
Foodstuffs intended for particular nutritional uses (13.0)-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)0.50000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)0.10000
Ready-to-eat savouries (15.0)1.10000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)-

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Endeavour Specialty Chemicals Ltd

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FRUTAROM USA INC,

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Jiangyin Healthway International Trade Co., Ltd

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Lluch Essence S.L.

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Natural Advantage

Manufacturer of natural flavor ingredients

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Penta International Corporation

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Riverside Aromatics Ltd.

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Robinson Brothers Limited

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Sigma-Aldrich

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R C Treatt and Co Ltd

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Ernesto Ventós S.A.

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WholeChem, LLC

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Potential Uses

FL chive FL garlic FL mango FL meat FL onion FL peanut FL pineapple FL scallion FL spearmint

Natural Occurrence

blood orange oil italy @ 12.30% Data chive onion bulb onion oil peanut roasted peanut shallot

Synonyms

di-n-propyl trisulfide dipropyl trisulphide dipropyl trisulphide extra dipropyltrisulfane propyl trisulfide 1-( propyl trithio) propane 1- propylsulfanyldisulfanylpropane propyltrithioporpane trisulfane, 1,3-dipropyl- trisulfide, dipropyl PubMed: Control of Panama disease of banana by rotating and intercropping with Chinese chive (Allium tuberosum Rottler): role of plant volatiles. PubMed: Novel approach for the determination of volatile compounds in processed onion by headspace gas chromatography-mass spectrometry (HS GC-MS). PubMed: The role of diallyl sulfides and dipropyl sulfides in the in vitro antimicrobial activity of the essential oil of garlic, Allium sativum L., and leek, Allium porrum L. PubMed: Composition and immunotoxicity activity of major essential oils from stems of Allium victorialis L. var. platyphyllum Makino against Aedes aegypti L. PubMed: Relationship between lipophilicity and inhibitory activity against cancer cell growth of nine kinds of alk(en)yl trisulfides with different side chains. PubMed: Chicken manure increased concentration of organic sulfur compounds in field-grown onions. PubMed: Diallyl trisulfide protects rats from carbon tetrachloride-induced liver injury. PubMed: Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells. PubMed: Ruminal fermentation of propylene glycol and glycerol. PubMed: Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. PubMed: Volatile compounds thermally generated from S-propylcysteine and S-propylcysteine sulfoxide-aroma precursors of Allium vegetables. PubMed: Enhancing effects of organosulfur compounds from garlic and onions on hepatocarcinogenesis in rats: association with increased cell proliferation and elevated ornithine decarboxylase activity.