menthyl formate

(5-methyl-2-propan-2-ylcyclohexyl) formate

CAS: 2230-90-2 C11 H20 O2 MW: 184.27880000

Identification

Namementhyl formate
CAS Number2230-90-2
EINECS218-768-2
FDA UNIISearch
Molecular FormulaC11 H20 O2
Molecular Weight184.27880000
Nikkaji NumberJ156.146D
CoE Number10751

Regulatory

JECFA Food Flavoring2246 menthyl formate
DG SANTE Food Flavourings09.618 menthyl formate
FEMA Number4509
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)2230-90-2 ; MENTHYL FORMATE

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00 sum of isomers
Food Chemicals Codex Listed No
Specific Gravity 0.93300 to 0.93900 @ 25.00 °C.
Pounds per Gallon - (est). 7.763 to 7.813
Refractive Index 1.44600 to 1.45200 @ 20.00 °C.
Melting Point 9.00 °C. @ 760.00 mm Hg
Boiling Point 219.00 to 220.00 °C. @ 760.00 mm Hg, 130.00 to 131.00 °C. @ 50.00 mm Hg
Vapor Pressure 0.070000 mmHg @ 25.00 °C. (est)
Flash Point 188.00 °F. TCC ( 86.67 °C. )
logP (o/w) 3.774 (est)
Soluble in alcohol
Insoluble in water
Similar Items note

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for menthyl formate usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.73 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)3900 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)1.00000
beverages(alcoholic)1.00000
breakfast cereal-
cheese-
chewing gum20.00000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy10.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy10.00000
soups-
sugar substitutes-
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)7.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)5.00000
Edible ices, including sherbet and sorbet (03.0)10.00000
Processed fruit (04.1)7.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)10.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)5.00000
Bakery wares (07.0)10.00000
Meat and meat products, including poultry and game (08.0)2.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)2.00000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)5.00000
Foodstuffs intended for particular nutritional uses (13.0)10.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)5.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)10.00000
Ready-to-eat savouries (15.0)20.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)5.00000

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

cyclohexanol, 5-methyl-2-(1-methylethyl)-, formate cyclohexanol,5-methyl-2-(1-methylethyl)-, 1-formate formic acid menthyl ester p- menth-3-yl methanoate para- menth-3-yl methanoate 5- methyl-2-(1-methylethyl)cyclohexanol formate (5- methyl-2-propan-2-ylcyclohexyl) formate 2-iso propyl-5-methyl cyclohexyl formate 2-iso propyl-5-methylcyclohexyl formate PubMed: Volatile compounds and sensory analysis of both harvests of double-cut Yakima peppermint (Mentha piperita L.). PubMed: Preparation of 2R, 3S, 2'R-nadolol enantiomer using S-(-)-menthyl chloroformate as a chiral derivatizing reagent. PubMed: Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives. PubMed: N-Menthoxycarbonylation combined with trimethylsilylation for enantioseparation of beta-blockers by achiral dual-column gas chromatography. PubMed: Comparison of different chloroformates for the derivatisation of seleno amino acids for gas chromatographic analysis. PubMed: Chirality and the origin of life: in situ enantiomeric separation for future space missions. PubMed: Chiral purity test of metoprolol enantiomer after derivatization with (-)-menthyl chloroformate by reversed-phase high performance liquid chromatography. PubMed: Chiral separation of beta-blockers after derivatization with (-)-menthyl chloroformate by reversed-phase high performance liquid chromatography. PubMed: A new HPLC technique for the separation of methocarbamol enantiomers. PubMed: Chloroformates in gas chromatography as general purpose derivatizing agents. PubMed: Assay of tocainide enantiomers in plasma by solid-phase extraction and indirect chiral high-performance liquid chromatography after derivatization with (-)-menthyl chloroformate. PubMed: Identification and determination of the enantiomers of moprolol and their metabolites in human urine by high-performance liquid chromatography and gas chromatography-mass spectrometry. PubMed: One-step conversion of amino acids into N-menthyloxycarbonyl alkyl ester derivatives for chiral gas chromatography. PubMed: Detection of amphetamine and methamphetamine in urine by gas chromatography/mass spectrometry following derivatization with (-)-menthyl chloroformate. PubMed: Stereospecific liquid chromatographic analysis of racemic adrenergic drugs utilizing precolumn derivatization with (-)-menthyl chloroformate. PubMed: Resolution of antihypertensive aryloxypropanolamine enantiomers by reversed-phase chromatography of (-)-menthyl chloroformate derivatives.