menthyl formate
(5-methyl-2-propan-2-ylcyclohexyl) formate
Identification
| Name | menthyl formate |
| CAS Number | 2230-90-2 |
| EINECS | 218-768-2 |
| FDA UNII | Search |
| Molecular Formula | C11 H20 O2 |
| Molecular Weight | 184.27880000 |
| Nikkaji Number | J156.146D |
| CoE Number | 10751 |
Regulatory
| JECFA Food Flavoring | 2246 menthyl formate |
| DG SANTE Food Flavourings | 09.618 menthyl formate |
| FEMA Number | 4509 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 2230-90-2 ; MENTHYL FORMATE |
Physical Properties
| Appearance | colorless clear liquid (est) |
| Assay | 95.00 to 100.00 sum of isomers |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.93300 to 0.93900 @ 25.00 °C. |
| Pounds per Gallon - (est). | 7.763 to 7.813 |
| Refractive Index | 1.44600 to 1.45200 @ 20.00 °C. |
| Melting Point | 9.00 °C. @ 760.00 mm Hg |
| Boiling Point | 219.00 to 220.00 °C. @ 760.00 mm Hg, 130.00 to 131.00 °C. @ 50.00 mm Hg |
| Vapor Pressure | 0.070000 mmHg @ 25.00 °C. (est) |
| Flash Point | 188.00 °F. TCC ( 86.67 °C. ) |
| logP (o/w) | 3.774 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
| Similar Items | note |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for menthyl formate usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.73 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 3900 (μg/person/day) |
| Threshold of Concern | 1800 (μg/person/day) |
| Structure Class | I |
| baked goods | - |
| beverages(nonalcoholic) | 1.00000 |
| beverages(alcoholic) | 1.00000 |
| breakfast cereal | - |
| cheese | - |
| chewing gum | 20.00000 |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | 10.00000 |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | 10.00000 |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
| Dairy products, excluding products of category 02.0 (01.0) | 7.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 5.00000 |
| Edible ices, including sherbet and sorbet (03.0) | 10.00000 |
| Processed fruit (04.1) | 7.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 10.00000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 5.00000 |
| Bakery wares (07.0) | 10.00000 |
| Meat and meat products, including poultry and game (08.0) | 2.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 2.00000 |
| Eggs and egg products (10.0) | - |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 5.00000 |
| Foodstuffs intended for particular nutritional uses (13.0) | 10.00000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | 5.00000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 10.00000 |
| Ready-to-eat savouries (15.0) | 20.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | 5.00000 |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
cyclohexanol, 5-methyl-2-(1-methylethyl)-, formate
cyclohexanol,5-methyl-2-(1-methylethyl)-, 1-formate
formic acid menthyl ester
p-
menth-3-yl methanoate
para-
menth-3-yl methanoate
5-
methyl-2-(1-methylethyl)cyclohexanol formate
(5-
methyl-2-propan-2-ylcyclohexyl) formate
2-iso
propyl-5-methyl cyclohexyl formate
2-iso
propyl-5-methylcyclohexyl formate
PubMed:
Volatile compounds and sensory analysis of both harvests of double-cut Yakima peppermint (Mentha piperita L.).
PubMed:
Preparation of 2R, 3S, 2'R-nadolol enantiomer using S-(-)-menthyl chloroformate as a chiral derivatizing reagent.
PubMed:
Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives.
PubMed:
N-Menthoxycarbonylation combined with trimethylsilylation for enantioseparation of beta-blockers by achiral dual-column gas chromatography.
PubMed:
Comparison of different chloroformates for the derivatisation of seleno amino acids for gas chromatographic analysis.
PubMed:
Chirality and the origin of life: in situ enantiomeric separation for future space missions.
PubMed:
Chiral purity test of metoprolol enantiomer after derivatization with (-)-menthyl chloroformate by reversed-phase high performance liquid chromatography.
PubMed:
Chiral separation of beta-blockers after derivatization with (-)-menthyl chloroformate by reversed-phase high performance liquid chromatography.
PubMed:
A new HPLC technique for the separation of methocarbamol enantiomers.
PubMed:
Chloroformates in gas chromatography as general purpose derivatizing agents.
PubMed:
Assay of tocainide enantiomers in plasma by solid-phase extraction and indirect chiral high-performance liquid chromatography after derivatization with (-)-menthyl chloroformate.
PubMed:
Identification and determination of the enantiomers of moprolol and their metabolites in human urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
PubMed:
One-step conversion of amino acids into N-menthyloxycarbonyl alkyl ester derivatives for chiral gas chromatography.
PubMed:
Detection of amphetamine and methamphetamine in urine by gas chromatography/mass spectrometry following derivatization with (-)-menthyl chloroformate.
PubMed:
Stereospecific liquid chromatographic analysis of racemic adrenergic drugs utilizing precolumn derivatization with (-)-menthyl chloroformate.
PubMed:
Resolution of antihypertensive aryloxypropanolamine enantiomers by reversed-phase chromatography of (-)-menthyl chloroformate derivatives.