Identification

Nameraspberry ketone methyl ether
IUPAC4-(4-methoxyphenyl)butan-2-one
CAS Number104-20-1
EINECS203-184-2
FDA UNIIGVG47S4S5V
Molecular FormulaC11 H14 O2
Molecular Weight178.23098000
MDL NumberMFCD00008791
Nikkaji NumberJ5.026A
Beilstein1869592
CoE Number163
XlogP32.10 (est)

Regulatory

JECFA Food Flavoring818 4-(p-methoxyphenyl)-2-butanone
DG SANTE Food Flavourings07.029 4-(4-methoxyphenyl)butan-2-one
FEMA Number2672
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)104-20-1 ; 4-(P-METHOXYPHENYL)-2-BUTANONE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to pale yellow clear oily liquid (est)
Assay 96.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 1.04100 to 1.05000 @ 25.00 °C.
Pounds per Gallon - (est). 8.662 to 8.737
Refractive Index 1.51500 to 1.52500 @ 20.00 °C.
Melting Point 8.00 °C. @ 760.00 mm Hg
Boiling Point 152.00 to 153.00 °C. @ 15.00 mm Hg, 276.00 to 278.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.004000 mmHg @ 25.00 °C. (est)
Vapor Density 6.1 ( Air = 1 )
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 1.852 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 324 hour(s) at 100.00 %
Odor Description
at 100.00 %.
at 5.00 %.
sweet/aniseed, floral/fruity, and cherry-raspberry on dilution
sweet, fruity, floral, anise, sweet raspberry, cherry note with rose nuances
fruity, aromatic, reminiscent of raspberry and blackberry
Odor sample from Elan Inc.
Taste Description
at 40.00 ppm.
anise
very sweet, raspberry, anisic, watery, slightly melon character
fruity, raspberry note

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 > 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for raspberry ketone methyl ether usage levels up to5.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)4.50 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)840.00 (μg/capita/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy10.00000
fruit ices10.00000
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

ACS International GmbH

Creativity Beyond Chemistry

Production • Distribution • Sourcing • Logistics • Consulting

View All Website +49 (0) 55 31 - 99 06-0 info@acsint.com

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

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Augustus Oils Ltd

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View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

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Beijing Lys Chemicals Co, LTD.

From Grams to Tons

Fine chemical high-tech company which contains R&D, production, and sales.

View All Website 86-10-68418738 jiayanyong@lyschem.com

Berje Inc.

Where the world comes to its senses

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BOC Sciences

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Charkit Chemical Corporation

The Specialty Chemical Specialists

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Elan Inc.

Legacy of Innovation

Highest quality natural and synthetic products.

View All Website +86 021 57448053 (Elan Shanghai) dpimentel@elan-chemical.com

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

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Global Essence Inc.

Preferred Partner

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Indukern, S.A. F&F Ingredients Division

Commitment to quality

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View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

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View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

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View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

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View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

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View All Website +39 039.685.6262

Natural Advantage

Manufacturer of natural flavor ingredients

With over 25 years experience in the flavor and food ingredient industries.

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Penta International Corporation

Chemistry innovation

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View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

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View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Sunaux International

Buy With Confidence

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Symrise AG

Always Insiring More

Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.

View All Website +49 5531 90 0 scentandcare@symrise.com

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.

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Taytonn ASCC Pte Ltd

Supplying Asia Pacific

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TCI AMERICA

Moving Your Chemistry Forward

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The Good Scents Company

Fragrance Creators

For your fragrance creations.

View All Website 414-764-2659 goodscnt@thegoodscentscompany.com

The Lermond Company

Your Sourcing Resource

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View All Website 201-896-3300 info@lermond.com

Tianjin Danjun International Trade Co., LTD.

Quality Products

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View All Website +86-15822601686 songshasha@danjunchem.com

R C Treatt and Co Ltd

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Ernesto Ventós S.A.

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Potential Uses

FR angel essence FR crabapple FL apple red apple FL apricot FL banana FL bergamot FL berry FL beverage FL blackberry blossom tropical blossom FL blueberry FR bouquet FL boysenberry FL butterscotch FR cabreuva wood FL cassia FL cherry FL cherry black cherry FL cherry blossom FL chocolate cacao FR christmas FR chypre FR colonia confection FL cookie FL cotton candy FR country meadow FR crabapple blossom FL cranberry FL cucumber FL currant FR daffodil FL dairy FR eglantine fantasy blends FR fern FR fetes FL fig FR fir balsam FR fir needle oil replacer FR forest FR frangipani plumeria FR freesia fruit dried fruit FL gardenia FL gooseberry FL grape FR heliotrope FL herbal FL hibiscus FL honeysuckle FR hyacinth FL jackfruit jam FL jasmin FR kiwi blossom FL licorice FR lilac FR lily FR lily of the valley FR linden flower FL loganberry FL lychee FR magnolia FL mango FR mango flower FL marshmallow FR melon FR moss FL mulberry FR musk FL necterine FL orange blossom FR pansy FL papaya FR passion blossom FL passion fruit FL peach FR peach blossom FR peony FL pineapple FL plum FR plum blossom FL pomegranate FL raspberry FL raspberry black raspberry FR redwood FL rose FR rose white rose rose wild rose FR scented stock FR stephanotis FL strawberry FR sweet pea FR tobacco FL tobacco FL tropical FR tuberose FL/FR valerian FL vanilla FL violet FR wallflower FR wisteria FR woody

Natural Occurrence

agarwood oil @ 2.40% Data PMC aloe wood anise seed

Synonyms

anisyl acetone nat. anisyl acetone p- anisyl acetone para- anisyl acetone anisyl acetone (natural) anisyl acetone FCC anisyl acetone natural anisyl acetone purified FCC anisyl acetone synthetic anisylacetone, p- bramble ketone butan-2-one, 4-(4-methoxyphenyl)- 2- butanone, 4-(4-methoxyphenyl)- 2- butanone, 4-(p-methoxyphenyl)- frambinon methyl ether (Symrise) frambinone methyl ether (Symrise) methoxy phenyl butanone p- methoxy phenyl butanone p- methoxy phenyl butanone natural 4-(4- methoxy-phenyl)-butan-2-one 4- methoxybenzyl acetone p- methoxybenzyl acetone para- methoxybenzyl acetone 4- methoxybenzylacetone methoxybenzylacetone, p- methoxyphenethyl methyl ketone methoxyphenethylmethyl ketone p- methoxyphenyl butanone para- methoxyphenyl butanone 4-(4- methoxyphenyl) butan-2-one 4-(4- methoxyphenyl)-2-butanone 4-(p- methoxyphenyl)-2-butanone 4-(para- methoxyphenyl)-2-butanone 1-(4- methoxyphenyl)-3-butanone 1-(p- methoxyphenyl)-3-butanone 1-(para- methoxyphenyl)-3-butanone 4-(4- methoxyphenyl)butan-2-one p- methoxyphenylbutanone para- methoxyphenylbutanone methyl oxanone raspberry ketone methyl ether raspberry ketone methylether PubMed: 5-Lipoxygenase Inhibition of the Fructus of Foeniculum vulgare and Its Constituents. PubMed: Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model. PubMed: Bioactivity-guided isolation of cytotoxic constituents from stem-bark of Premna tomentosa. PubMed: Manganese peroxidase-catalyzed oxidative degradation of vanillylacetone. PubMed: [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood]. PubMed: Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana. PubMed: Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum. PubMed: Aroma extract dilution analysis of cv. Meeker (Rubus idaeus L.) red raspberries from Oregon and Washington. PubMed: Optimization of a chemical attractant for Epicometis (Tropinota) hirta Poda. PubMed: Biotransformation of terodiline I. Identification of metabolites in dog urine by mass spectrometry. PubMed: Homologs of dopa, alpha-methyldopa, and dopamine as potential cardiovascular drugs. PubMed: New Synthetic Lures for the Male Melon Fly.