phenyl propionaldehyde
propionaidehyde, phenyl-
Identification
| Name | phenyl propionaldehyde |
| CAS Number | 1335-10-0 |
| EINECS | 215-620-9 |
| FDA UNII | LP1E86N30T |
| Molecular Formula | C9 H10 O |
| Molecular Weight | 134.17790000 |
| MDL Number | MFCD00007021 |
| Nikkaji Number | J36.950K |
| Beilstein | 1071910 |
| XlogP3 | 1.30 (est) |
Regulatory
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 217.00 to 218.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.131000 mmHg @ 25.00 °C. (est) |
| Flash Point | 203.00 °F. TCC ( 95.00 °C. ) (est) |
| logP (o/w) | 1.780 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for phenyl propionaldehyde flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
dihydrocinnamaldehyde
hydrocinnamic aldehyde
hydrocinnamyl aldehyde
hydrocinnamylaldehyde
phenyl propanal
3-
phenylpropanal
phenylpropionaldehyde
propionaidehyde, phenyl-
PubMed:
Formation of complex natural flavours by biotransformation of apple pomace with basidiomycetes.
PubMed:
From a remarkable manifestation of polar effects in a radical fragmentation to the convergent synthesis of highly functionalized ketones.
PubMed:
Rh-catalyzed linear hydroformylation of styrene.
PubMed:
Enhancement of the promiscuous aldolase and dehydration activities of 4-oxalocrotonate tautomerase by protein engineering.
PubMed:
Characterization and further stabilization of a new anti-prelog specific alcohol dehydrogenase from Thermus thermophilus HB27 for asymmetric reduction of carbonyl compounds.
PubMed:
A computational reinvestigation of the formation of N-alkylpyrroles via intermolecular redox amination.
PubMed:
In vivo cytokine modulatory effects of cinnamaldehyde, the major constituent of leaf essential oil from Cinnamomum osmophloeum Kaneh.
PubMed:
A site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity.
PubMed:
Well-defined N-heterocyclic carbene silver halides of 1-cyclohexyl-3-arylmethylimidazolylidenes: synthesis, structure and catalysis in A3-reaction of aldehydes, amines and alkynes.
PubMed:
Formation of multi-stereogenic centers using a catalytic diastereoselective Henry reaction.
PubMed:
Olfactory sensitivity for sperm-attractant aromatic aldehydes: a comparative study in human subjects and spider monkeys.
PubMed:
Origin of pressure effects on regioselectivity and enantioselectivity in the rhodium-catalyzed hydroformylation of styrene with (S,S,S)-BisDiazaphos.
PubMed:
The development and evaluation of a conducting matrix for the electrochemical regeneration of the immobilised co-factor NAD(H) under continuous flow.
PubMed:
Emission pattern of semi-volatile organic compounds from recycled styrenic polymers using headspace solid-phase microextraction gas chromatography-mass spectrometry.
PubMed:
Halonium ion-assisted deiodination of styrene-based vicinal iodohydrins followed by rearrangement through phenyl migration.
PubMed:
Antimicrobial activity of the essential oil obtained from roots and chemical composition of the volatile constituents from the roots, stems, and leaves of Ballota nigra from Serbia.
PubMed:
Substrate specificity of human and yeast aldehyde dehydrogenases.
PubMed:
Purification and characterization of aldehyde dehydrogenase with a broad substrate specificity originated from 2-phenylethanol-assimilating Brevibacterium sp. KU1309.
PubMed:
Mechanistic and structural studies of apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase At5g16970.
PubMed:
Pinus taeda phenylpropenal double-bond reductase: purification, cDNA cloning, heterologous expression in Escherichia coli, and subcellular localization in P. taeda.
PubMed:
Stability and comparative metabolism of selected felbamate metabolites and postulated fluorofelbamate metabolites by postmitochondrial suspensions.
PubMed:
Oxidative aldehyde deformylation catalyzed by NADPH-cytochrome P450 reductase and the flavoprotein domain of neuronal nitric oxide synthase.
PubMed:
Can the pi-facial selectivity of solvation be predicted by atomistic simulation?
PubMed:
Inversion of stereoselectivity by applying mutants of the hydroxynitrile lyase from Manihot esculenta.
PubMed:
Strategy for the synthesis of polymeric supports with hydrazone linkers for solid-phase alkylation of ketones and aldehydes.
PubMed:
Investigating the role of 2-phenylpropenal in felbamate-induced idiosyncratic drug reactions.
PubMed:
Enantioselective catalysis of the hetero-Diels-Alder reaction between Brassard's diene and aldehydes by hydrogen-bonding activation: a one-step synthesis of (S)-(+)-dihydrokawain.
PubMed:
Development of highly diastereo- and enantioselective direct asymmetric aldol reaction of a glycinate Schiff base with aldehydes catalyzed by chiral quaternary ammonium salts.
PubMed:
Reversal of enantioselectivity in the hydroformylation of styrene with [2S,4S-BDPP]Pt(SnCl3)Cl at high temperature arises from a change in the enantioselective-determining step.
PubMed:
Cumene oxidation by cis-[RuIV(bpy)2(py)(O)]2+, revisited.
PubMed:
Chiral aldehydes in hydrocarbons: diastereoselective nucleophilic addition, NMR, and CD spectroscopy reveal dynamic solvation effects.
PubMed:
The arduous way to the egg: follow the nose.
PubMed:
SuperQuat N-acyl-5,5-dimethyloxazolidin-2-ones for the asymmetric synthesis of alpha-alkyl and beta-alkyl aldehydes.
PubMed:
Total synthesis of (+)-strictifolione.
PubMed:
Reductive activation of dioxygen by a myoglobin reconstituted with a flavohemin.
PubMed:
High yield synthesis of nitriles by a new enzyme, phenylacetaldoxime dehydratase, from Bacillus sp. strain OxB-1.
PubMed:
Diastereoselective inter- and intramolecular pinacol coupling of aldehydes promoted by monomeric titanocene(II) complex Cp(2)TiPh.
PubMed:
Felkin-Anh stereoselectivity in cycloadditions of acetylketene: evidence for a concerted, pseudopericyclic pathway
PubMed:
Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes.
PubMed:
EPR spectrometry of cytochrome P450 2B4: effects of mutations and substrate binding.
PubMed:
Catalysis by amino acid-derived tetracoordinate complexes: enantioselective addition of dialkylzincs to aliphatic and aromatic aldehydes.
PubMed:
First asymmetric synthesis of a 6-alkoxy-5,6-dihydro-1,3-oxazine: a promising enantioselective route to beta-amido aldehydes
PubMed:
The synthesis, in vitro reactivity, and evidence for formation in humans of 5-phenyl-1,3-oxazinane-2,4-dione, a metabolite of felbamate.
PubMed:
Discrete species of activated oxygen yield different cytochrome P450 heme adducts from aldehydes.
PubMed:
Synthesis and cytotoxic activity of N-substituted thiosemicarbazones of 3-(3,4-methylenedioxy)phenylpropanal.
PubMed:
Mechanism-based inactivation of cytochrome P450 2B4 by aldehydes: relationship to aldehyde deformylation via a peroxyhemiacetal intermediate.
PubMed:
Asymmetric Electroreduction of Ketone and Aldehyde Derivatives to the Corresponding Alcohols Using Alcohol Dehydrogenase as an Electrocatalyst.
PubMed:
Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration.
PubMed:
Synthesis and in vitro reactivity of 3-carbamoyl-2-phenylpropionaldehyde and 2-phenylpropenal: putative reactive metabolites of felbamate.
PubMed:
Hepatic microsomal oxygenation of aldehydes to carboxylic acids.
PubMed:
Metabolic conversion of 2-propylpentanal acetals to valproic acid in vitro. Model prodrugs of carboxylic acid agents.
PubMed:
Reductions of 2-enals, dehydrogenation of saturated aldehydes and their racemisation.
PubMed:
Geometric specificity of alcohol dehydrogenases and its potential for separation of trans and cis isomers of unsaturated aldehydes.
PubMed:
Nicotinamide adenine dinucleotide phosphate-decanaldehyde adduct as an inhibitor of beef brain NADP-linked aldehyde reductase.
PubMed:
Biosynthesis of mustard oil glucosides: conversion of phenylacetaldehyde oxime and 3-phenylpropionaldehyde oxime to glucotropaeolin and gluconasturtiin.