helichrysetin
chalcone, 4,4',6'-trihydroxy-2'-methoxy-
Identification
| Name | helichrysetin |
| IUPAC | (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| CAS Number | 62014-87-3 |
| FDA UNII | MJ0KMG7AW4 |
| Molecular Formula | C16 H14 O5 |
| Molecular Weight | 286.28358000 |
| Nikkaji Number | J947.641E |
Regulatory
Physical Properties
| Appearance | yellow powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 532.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 394.00 °F. TCC ( 201.00 °C. ) (est) |
| logP (o/w) | 3.080 (est) |
| Soluble in | water, 132.7 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for helichrysetin usage levels up to | not for fragrance use. |
| Recommendation for helichrysetin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
chalcone, 4,4',6'-trihydroxy-2'-methoxy-
(2E)-1-(2,4-
dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
1-(2,4-
dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
(2E)-1-(2,4-
dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
(E)-1-(2,4-
dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
helichysetin
2-
propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
PubMed:
Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells.
PubMed:
Synthesis, cytotoxicity, anti-oxidative and anti-inflammatory activity of chalcones and influence of A-ring modifications on the pharmacological effect.
PubMed:
Aromatherapy research and practice.
PubMed:
Natural and non-natural prenylated chalcones: synthesis, cytotoxicity and anti-oxidative activity.
PubMed:
Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata.
PubMed:
Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin.