aspergillic acid

1-hydroxy-6-(1-methylpropyl)-3-(2-methylpropyl)-2(1H)-pyrazinone

CAS: 490-02-8 C12 H20 N2 O2 MW: 224.30380000

Identification

Nameaspergillic acid
CAS Number490-02-8
FDA UNII41YKP41T0A
Molecular FormulaC12 H20 N2 O2
Molecular Weight224.30380000
MDL NumberMFCD00597205
Nikkaji NumberJ12.576H
Beilstein0882390

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 98.00 °C. @ 760.00 mm Hg
Boiling Point 336.30 °C. @ 760.00 mm Hg (est)
Flash Point 315.00 °F. TCC ( 157.20 °C. ) (est)
logP (o/w) 1.810 (est)
Soluble in water, 929.3 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityintraperitoneal-mouse LDLo 150 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for aspergillic acid usage levels up tonot for fragrance use.
Recommendation for aspergillic acid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

6- butan-2-yl-1-hydroxy-3-(2-methylpropyl)pyrazin-2-one 6-sec- butyl-1-hydroxy-3-isobutyl-2(1h)-pyrazinone granegillin 1- hydroxy-6-(1-methyl propyl)-3-(2-methyl propyl)-2(1H)-pyrazinone 1- hydroxy-6-(1-methylpropyl)-3-(2-methylpropyl)-2(1H)-pyrazinone pyrazinol, 6-(1-methylpropyl)-3-(2-methylpropyl)-, 1-oxide, (+)- 2(1H)- pyrazinone, 1-hydroxy-6-(1-methylpropyl)-3-(2-methylpropyl)- 2(1H)- pyrazinone, 1-hydroxy-6-(1-methylpropyl)-3-(2-methylpropyl)- (+)- (9CI) PubMed: New mycotoxins from marine-derived fungus Aspergillus sp. SCSGAF0093. PubMed: Biosynthesis, characterization and biological evalutation of Fe(III) and Cu(II) complexes of neoaspergillic acid, a hydroxamate siderophore produced by co-cultures of two marine-derived mangrove epiphytic fungi. PubMed: Aspergillus novoparasiticus: a new clinical species of the section Flavi. PubMed: Rapid analysis of fungal cultures and dried figs for secondary metabolites by LC/TOF-MS. PubMed: Two novel aflatoxin-producing Aspergillus species from Argentinean peanuts. PubMed: Taxonomic comparison of three different groups of aflatoxin producers and a new efficient producer of aflatoxin B1, sterigmatocystin and 3-O-methylsterigmatocystin, Aspergillus rambellii sp. nov. PubMed: Fungal populations and mycotoxins in silage in Assiut and Sohag governorates in Egypt, with a special reference to characteristic Aspergilli toxins. PubMed: [Mystery of fermented foods--There are friendly molds too!]. PubMed: Aspergillic acids produced by mixed cultures of Aspergillus flavus and Aspergillus nidulans. PubMed: Toxicity, analysis, and production of aspergillic acid and its analogues. PubMed: New analogues of aspergillic acid derived from methionine. PubMed: Nitrification of aspartate by Aspergillus flavus. PubMed: Biosynthesis of compounds similar to aspergillic acid. PubMed: [Synthesis of DL-aspergillic acid and deoxyaspergillic acid]. PubMed: Interference with valine and isoleucine biosynthesis by cyclic hydroxamic acids. PubMed: Biosynthesis of aspergillic acid. PubMed: Aspergillic acid; an antibiotic substance produced by Aspergillus flavus. PubMed: Synthesis of pyrazine cyclic hydroxamic acids related to aspergillic acid. PubMed: Analogs of aspergillic acid; various antibacterial heterocyclic hydroxamic acids. PubMed: Analogs of aspergillic acid; the tautomerism of the hydroxypyridine-N-oxides. PubMed: On the mode of iron binding by siderophilin, conalbumin, hydroxylamine, aspergillic acid, and other hydroxamic acids. PubMed: Structure of the antibacterial compound, aspergillic acid. PubMed: On the nature of iron binding by siderophilin, conlbumin, hydroxylamine, aspergillic acid, and related hydroxamic acids. PubMed: The rapid recognition of aspergillic acid. PubMed: The Rapid Recognition of Aspergillic Acid. PubMed: Production of Aspergillic Acid by Surface Cultures of Aspergillus flavus. PubMed: Pyrazine derivatives; a synthesis of a racemic 2-hydroxy-3 : 6-di-sec.-butylpyrazine and its relationship to deoxyaspergillic acid. PubMed: The antibiotic properties of a bismuth aspergillic acid complex. PubMed: Potentiation of the antibiotic activity of aspergillic acid by bismuth. PubMed: Potentiation of the Antibiotic Activity of Aspergillic Acid by Bismuth. PubMed: The effect of cobalt on the antitubercular activity of aspergillic acid. PubMed: Studies on Aspergillus Flavus: I. Biological Properties of Crude and Purified Aspergillic Acid. PubMed: Studies on Antibacterial Products Formed by Molds: I. Aspergillic Acid, a Product of a Strain of Aspergillus Flavus.