methyl ethyl pyruvic acid

3-methyl-2-oxopentanoic acid

CAS: 1460-34-0 C6 H10 O3 MW: 130.14330000

Identification

Namemethyl ethyl pyruvic acid
CAS Number1460-34-0
EINECS215-955-0
FDA UNII787T50HCIV
Molecular FormulaC6 H10 O3
Molecular Weight130.14330000
MDL NumberMFCD00002582
Nikkaji NumberJ39.560I
Beilstein3904281
CoE Number10146

Regulatory

JECFA Food Flavoring632 3-methyl-2-oxopentanoic acid
FEMA Number3870
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)1460-34-0 ; 3-METHYL-2-OXOPENTANOIC ACID

Physical Properties

Appearance white crystalline powder (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 41.00 to 42.00 °C. @ 760.00 mm Hg
Boiling Point 233.00 °C. @ 760.00 mm Hg, 84.00 °C. @ 18.00 mm Hg
Vapor Pressure 0.239000 mmHg @ 25.00 °C. (est)
Flash Point 182.00 °F. TCC ( 83.33 °C. )
logP (o/w) 0.133 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage refrigerate in tightly sealed containers.
Soluble in water, 1.676e+005 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for methyl ethyl pyruvic acid usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)1.00000
beverages(alcoholic)0.50000
breakfast cereal-
cheese0.50000
chewing gum1.00000
condiments / relishes0.50000
confectionery froastings1.00000
egg products-
fats / oils0.30000
fish products-
frozen dairy1.00000
fruit ices1.00000
gelatins / puddings0.50000
granulated sugar-
gravies1.00000
hard candy1.00000
imitation dairy0.50000
instant coffee / tea0.10000
jams / jellies1.00000
meat products-
milk products0.50000
nut products-
other grains-
poultry-
processed fruits0.10000
processed vegetables0.10000
reconstituted vegetables1.00000
seasonings / flavors50.00000
snack foods-
soft candy0.10000
soups1.00000
sugar substitutes0.50000
sweet sauces1.00000

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Potential Uses

None Found

Natural Occurrence

asparagus cooked white asparagus cheese fontina cheese PMC cocoa

Synonyms

3- ethyl-3-methyl pyruvic acid 3- ethyl-3-methylpyruvic acid alpha-keto-beta- methyl valeric acid 3- methyl-2-oxo-pentanoic acid 3- methyl-2-oxo-valeric acid 3- methyl-2-oxopentanoic acid 3- methyl-2-oxovaleric acid 2-oxo-3- methyl-N-valeric acid a-keto-b- methyl-N-valeric acid a-oxo-b- methyl-N-valeric acid methylethylpyruvic acid 2-oxo-3- methylpentanoic acid a-keto-b- methylvaleric acid a-oxo-b- methylvaleric acid alpha-keto-beta- methylvaleric acid pentanoic acid, 3-methyl-2-oxo- PubMed: Metabolomics diagnostic approach to mustard airway diseases: a preliminary study. PubMed: Plasma metabolites associated with type 2 diabetes in a Swedish population: a case-control study nested in a prospective cohort. PubMed: Physiological levels of formate activate mitochondrial superoxide/hydrogen peroxide release from mouse liver mitochondria. PubMed: Examination of the superoxide/hydrogen peroxide forming and quenching potential of mouse liver mitochondria. PubMed: A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis. PubMed: Nontargeted LC-MS Metabolomics Approach for Metabolic Profiling of Plasma and Urine from Pigs Fed Branched Chain Amino Acids for Maximum Growth Performance. PubMed: Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. PubMed: Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates. PubMed: A computational approach to enzyme design: predicting ω-aminotransferase catalytic activity using docking and MM-GBSA scoring. PubMed: Effect of amino acids on the formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in creatinine/phenylalanine and creatinine/phenylalanine/4-oxo-2-nonenal reaction mixtures. PubMed: Chiral bis(imidazolinyl)phenyl NCN pincer rhodium(III) catalysts for enantioselective allylation of aldehydes and carbonyl-ene reaction of trifluoropyruvates. PubMed: Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling. PubMed: Determination of α-keto acids in pork meat and Iberian ham via tandem mass spectrometry. PubMed: The role of free amino acids in semen of rainbow trout Oncorhynchus mykiss and carp Cyprinus carpio. PubMed: Joint experimental and DFT study of the gas-phase unimolecular elimination kinetic of methyl trifluoropyruvate. PubMed: Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia. PubMed: S-alk(en)yl-L-cysteine sulfoxides and relative pungency measurements of photosynthetic and nonphotosynthetic tissues of Allium porrum. PubMed: Methyltrifluoropyruvate imines possessing N-oxalyl and N-phosphonoformyl groups--precursors to a variety of alpha-CF3-alpha-amino acid derivatives. PubMed: The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro. PubMed: Stereoselective biosynthesis of chloroarylpropane diols by the basidiomycete Bjerkandera adusta: exploring the roles of amino acids, pyruvate, glycerol and phenyl acetyl carbinol. PubMed: Ethyl pyruvate: a novel anti-inflammatory agent. PubMed: Pharmacologically active ellagitannins from Terminalia myriocarpa. PubMed: Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. PubMed: Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin. PubMed: Reactions of 4-aryl-1-hydrazinophthalazines with carbonyl compounds. PubMed: Model studies on the analysis of pyruvic acid acetal-containing polysaccharides by the reductive-cleavage method.