diacetic acid
acetonecarboxylic acid
Identification
| Name | diacetic acid |
| IUPAC | 3-oxobutanoic acid |
| CAS Number | 541-50-4 |
| FDA UNII | 4ZI204Y1MC |
| Molecular Formula | C4 H6 O3 |
| Molecular Weight | 102.08942000 |
| Nikkaji Number | J4.508J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 36.00 to 37.00 °C. @ 760.00 mm Hg |
| Boiling Point | 237.00 to 239.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.218000 mmHg @ 25.00 °C. |
| Flash Point | 233.00 °F. TCC ( 111.67 °C. ) |
| logP (o/w) | -0.467 (est) |
| Soluble in | water, 1.00E+06 mg/L @ 20 °C (exp) |
| Similar Items | note |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for diacetic acid usage levels up to | not for fragrance use. |
| Recommendation for diacetic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
AAE
acetoacetic acid
acetonecarboxylic acid
acetylacetic acid
3-oxo
butanoic acid
butanoic acid, 3-oxo-
3-keto
butyric acid
beta-keto
butyric acid
LIN
PubMed:
Ã-Phenylethylamine as a novel nutrient treatment to reduce bacterial contamination due to Escherichia coli O157:H7 on beef meat.
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HPLC-DAD-ESI-MS/MS characterization of pyranoanthocyanins pigments formed in model wine.
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Chemical evaluation of HBED/Fe(3+) and the novel HJB/Fe(3+) chelates as fertilizers to alleviate iron chlorosis.
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Improvement of natural isolates of Saccharomyces cerevisiae strains for synthesis of a chiral building block using classic genetics.
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The influence of small doses of paracetamol on rabbit liver.
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Isolation and structural characterization of new anthocyanin-derived yellow pigments in aged red wines.
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Daily changes in parameters of energy metabolism in brain of rainbow trout: dependence on feeding.
PubMed:
[Lactation and alcohol: clinical and nutritional effects].
PubMed:
Repeated bouts of high-intensity exercise and muscle glycogen sparing in the rat.
PubMed:
Anticipatory changes in liver metabolism and entrainment of insulin, glucagon, and corticosterone in food-restricted rats.
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Lipid turnover in alcoholics before and after an ethanol load.
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Influence of lasalocid, cationomycin and feeding frequency on the postprandial kinetics of some plasma parameters in the rumen vein, portal vein and mesenteric artery of sheep.
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Plasma ketone levels in neonatal calves fed medium chain triglycerides in milk.
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Postprandial de novo lipogenesis in alcoholic liver cirrhosis: relationship with fuel homeostasis and nutritional status.
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Scintigraphic study of gallbladder emptying and duodenogastric reflux during non-ulcerous dyspepsia.
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Metabolic effects of a single administration of growth hormone on lipid and carbohydrate metabolism in normal-weight and obese subjects.
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Lipogenesis from ketone bodies in perfused livers from streptozocin-induced diabetic rats.
PubMed:
Response of ketone body metabolism to exercise during transition from postabsorptive to fasted state.
PubMed:
Medium-chain triglycerides in infant formulas and their relation to plasma ketone body concentrations.
PubMed:
Effect of hypoxia and short-term fasting on the plasma acetoacetic acid level in rats of different ages.
PubMed:
Regulation of food intake by hepatic oxidative metabolism.
PubMed:
Ketone kinetics and D-(-)-3-hydroxybutyrate-induced inhibition of feeding in rats.
PubMed:
Reduced and compensatory growth: endocrine and metabolic changes during food restriction and refeeding in steers.
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Artifactual elevation of serum creatinine level due to fasting.
PubMed:
Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food.
PubMed:
Different effects of subcutaneous D,L-3-hydroxybutyrate and acetoacetate injections on food intake in rats.
PubMed:
Metabolic and endocrine responses of infants to breast milk and formulas.
PubMed:
Substrate concentration changes during pregnancy in the guinea pig studied under unstressed steady state conditions.
PubMed:
Intravenous feeding of the rat with short chain fatty acid esters. II. Monoacetoacetin.
PubMed:
THE EFFECT OF INSULIN AND DEPRIVATION OF FOOD ON METABOLISM OF ACETOACETIC ACID BY MUSCLE.