6-hydroxyhexanoic acid
hexanoic acid, 6-hydroxy-
Identification
| Name | 6-hydroxyhexanoic acid |
| CAS Number | 1191-25-9 |
| FDA UNII | 3Y3OX37NM8 |
| Molecular Formula | C6 H12 O3 |
| Molecular Weight | 132.15924000 |
| MDL Number | MFCD00046560 |
| Nikkaji Number | J262.001D |
| XlogP3 | -0.40 (est) |
Regulatory
Physical Properties
| Appearance | colorless to pale yellow clear liquid to solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 272.00 to 273.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point | 271.00 °F. TCC ( 132.90 °C. ) (est) |
| logP (o/w) | -0.191 (est) |
| Soluble in | water, 2.287e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 6-hydroxyhexanoic acid usage levels up to | not for fragrance use. |
| Recommendation for 6-hydroxyhexanoic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
hexanoic acid, 6-hydroxy-
6-
hydroxy caproic acid
6-
hydroxycaproic acid
epsilon-
hydroxycaproic acid
6-
hydroxycaproicacid
PubMed:
Biodegradation of poly(ε-caprolactone) (PCL) by a new Penicillium oxalicum strain DSYD05-1.
PubMed:
Growth of human fibroblasts in the presence of 6-hydroxyhexanoic acid.
PubMed:
Synthesis and characterization of a novel PNIPAAm-based copolymer with hydrolysis-dependent thermosensitivity.
PubMed:
Synthesis of polycaprolactone: a review.
PubMed:
Cartilage tissue engineering for auricular reconstruction: in vitro evaluation of potential genotoxic and cytotoxic effects of scaffold materials.
PubMed:
Origin of byproducts during the catalytic autoxidation of cyclohexane.
PubMed:
The formation of byproducts in the autoxidation of cyclohexane.
PubMed:
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with size-exclusion chromatographic fractionation for structural characterization of synthetic aliphatic copolyesters.
PubMed:
Mild, solvent-free omega-hydroxy acid polycondensations catalyzed by candida antarctica lipase B.
PubMed:
Qualitative and quantitative solid-phase microextraction gas chromatographic-mass spectrometric determination of the low-molecular-mass compounds released from poly(vinyl chloride)/polycaprolactone-polycarbonate during ageing.
PubMed:
Microbial/enzymatic synthesis of chiral drug intermediates.
PubMed:
Enzymatic synthesis of chiral intermediates for Omapatrilat, an antihypertensive drug.
PubMed:
Synthesis of a novel ether-bridged GM3-lactone analogue as a target for an antibody-based cancer therapy.
PubMed:
Enzymatic synthesis of L-6-hydroxynorleucine.
PubMed:
Crystallization behavior and thermal properties of melt-crystallized poly[(R)-3-hydroxybutyric acid-co-6-hydroxyhexanoic acid] films.
PubMed:
Metabolism of 2-ethylhexanoic acid administered orally or dermally to the female Fischer 344 rat.
PubMed:
Capillary zone electrophoresis in normal or reverse polarity separation modes for the analysis of hydroxy acid oligomers in neutral phosphate buffer.
PubMed:
Substrate specificities of poly(hydroxyalkanoate)-degrading bacteria and active site studies on the extracellular poly(3-hydroxyoctanoic acid) depolymerase of Pseudomonas fluorescens GK13.
PubMed:
Identification of the main metabolites of 2-ethylhexanoic acid in rat urine using gas chromatography-mass spectrometry.
PubMed:
Protein modification by diazotized arsanilic acid: synthesis and characterization of the phenylthiohydantoin derivatives of azobenzene arsonate-coupled tyrosine, histidine, and lysine residues and their sequential allotment in labeled peptides.
PubMed:
Formation of epsilon-hydroxycaproate and epsilon-aminocaproate from N-nitrosohexamethyleneimine: evidence that microsomal alpha-hydroxylation of cyclic nitrosamines may not always involve the insertion of molecular oxygen into the substrate.
PubMed:
Bacterial formation and metabolism of 6-hydroxyhexanoate: evidence of a potential role for omega-oxidation.
PubMed:
Microbial production of vitamin B12 antimetabolites. IV. Isolation and identification of 4-keto-5-amino-6-hydroxyhexanoic acid.