6-hydroxyhexanoic acid

hexanoic acid, 6-hydroxy-

CAS: 1191-25-9 C6 H12 O3 MW: 132.15924000

Identification

Name6-hydroxyhexanoic acid
CAS Number1191-25-9
FDA UNII3Y3OX37NM8
Molecular FormulaC6 H12 O3
Molecular Weight132.15924000
MDL NumberMFCD00046560
Nikkaji NumberJ262.001D
XlogP3-0.40 (est)

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid to solid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 272.00 to 273.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Flash Point 271.00 °F. TCC ( 132.90 °C. ) (est)
logP (o/w) -0.191 (est)
Soluble in water, 2.287e+005 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 6-hydroxyhexanoic acid usage levels up tonot for fragrance use.
Recommendation for 6-hydroxyhexanoic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

hexanoic acid, 6-hydroxy- 6- hydroxy caproic acid 6- hydroxycaproic acid epsilon- hydroxycaproic acid 6- hydroxycaproicacid PubMed: Biodegradation of poly(ε-caprolactone) (PCL) by a new Penicillium oxalicum strain DSYD05-1. PubMed: Growth of human fibroblasts in the presence of 6-hydroxyhexanoic acid. PubMed: Synthesis and characterization of a novel PNIPAAm-based copolymer with hydrolysis-dependent thermosensitivity. PubMed: Synthesis of polycaprolactone: a review. PubMed: Cartilage tissue engineering for auricular reconstruction: in vitro evaluation of potential genotoxic and cytotoxic effects of scaffold materials. PubMed: Origin of byproducts during the catalytic autoxidation of cyclohexane. PubMed: The formation of byproducts in the autoxidation of cyclohexane. PubMed: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with size-exclusion chromatographic fractionation for structural characterization of synthetic aliphatic copolyesters. PubMed: Mild, solvent-free omega-hydroxy acid polycondensations catalyzed by candida antarctica lipase B. PubMed: Qualitative and quantitative solid-phase microextraction gas chromatographic-mass spectrometric determination of the low-molecular-mass compounds released from poly(vinyl chloride)/polycaprolactone-polycarbonate during ageing. PubMed: Microbial/enzymatic synthesis of chiral drug intermediates. PubMed: Enzymatic synthesis of chiral intermediates for Omapatrilat, an antihypertensive drug. PubMed: Synthesis of a novel ether-bridged GM3-lactone analogue as a target for an antibody-based cancer therapy. PubMed: Enzymatic synthesis of L-6-hydroxynorleucine. PubMed: Crystallization behavior and thermal properties of melt-crystallized poly[(R)-3-hydroxybutyric acid-co-6-hydroxyhexanoic acid] films. PubMed: Metabolism of 2-ethylhexanoic acid administered orally or dermally to the female Fischer 344 rat. PubMed: Capillary zone electrophoresis in normal or reverse polarity separation modes for the analysis of hydroxy acid oligomers in neutral phosphate buffer. PubMed: Substrate specificities of poly(hydroxyalkanoate)-degrading bacteria and active site studies on the extracellular poly(3-hydroxyoctanoic acid) depolymerase of Pseudomonas fluorescens GK13. PubMed: Identification of the main metabolites of 2-ethylhexanoic acid in rat urine using gas chromatography-mass spectrometry. PubMed: Protein modification by diazotized arsanilic acid: synthesis and characterization of the phenylthiohydantoin derivatives of azobenzene arsonate-coupled tyrosine, histidine, and lysine residues and their sequential allotment in labeled peptides. PubMed: Formation of epsilon-hydroxycaproate and epsilon-aminocaproate from N-nitrosohexamethyleneimine: evidence that microsomal alpha-hydroxylation of cyclic nitrosamines may not always involve the insertion of molecular oxygen into the substrate. PubMed: Bacterial formation and metabolism of 6-hydroxyhexanoate: evidence of a potential role for omega-oxidation. PubMed: Microbial production of vitamin B12 antimetabolites. IV. Isolation and identification of 4-keto-5-amino-6-hydroxyhexanoic acid.