Synonyms
2,4-
dihydroxy-2-methyl pentane
2,4-
dihydroxy-2-methylpentane
1,3-
dimethyl-3-hydroxybutanol
diolane
hexylen glycol
(±)-
hexylene glycol
isol
2-
methyl pentane-2,4-diol
2-
methyl-2,4-pentandiol
4-
methyl-2,4-pentane diol
2-
methyl-2,4-pentanediol
2-
methylpentane-2,4-diol
2,4-
pentanediol, 2-methyl-
pinakon
1,1,3-
trimethyl trimethylene diol
alpha,alpha,alpha'-
trimethyl trimethylene glycol
1,1,3-
trimethyl-1,3-propanediol
1,3,3-
trimethyl-1,3-propanediol
1,1,3-
trimethyltrimethylenediol
PubMed:
Refolding of SDS-denatured proteins using amphipathic cosolvents and osmolytes.
PubMed:
Crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Thermus thermophilus HB8.
PubMed:
Crystal structure of silkworm Bombyx mori JHBP in complex with 2-methyl-2,4-pentanediol: plasticity of JH-binding pocket and ligand-induced conformational change of the second cavity in JHBP.
PubMed:
Nanolitre-scale crystallization using acoustic liquid-transfer technology.
PubMed:
Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases.
PubMed:
Structure-property relationship in new photo-cured dimethacrylate-based dental resins.
PubMed:
A strategy for purifying glutathione S-transferase in the presence of sodium dodecyl sulfate.
PubMed:
Atomic force microscopy imaging of human metaphase chromosomes in liquid.
PubMed:
The structure of human ubiquitin in 2-methyl-2,4-pentanediol: a new conformational switch.
PubMed:
2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal α-hemolysin into heptameric pore structure.
PubMed:
Diffusion in ternary aqueous systems containing human serum albumin and precipitants of different classes.
PubMed:
Properties of a new mouthrinse for patients receiving radiation therapy.
PubMed:
PagP crystallized from SDS/cosolvent reveals the route for phospholipid access to the hydrocarbon ruler.
PubMed:
Formulation of creams with betamethasone dipropionate: evaluation of chemical stability.
PubMed:
Contact urticaria with systemic symptoms due to hexylene glycol in a topical corticosteroid: case report and review of hypersensitivity to glycols.
PubMed:
Tryptophan as a three-way switch in regulating the function of the secretory signalling glycoprotein (SPS-40) from mammary glands: structure of SPS-40 complexed with 2-methylpentane-2,4-diol at 1.6 A resolution.
PubMed:
Protecting role of cosolvents in protein denaturation by SDS: a structural study.
PubMed:
Efficient low-power heteronuclear decoupling in 13C high-resolution solid-state NMR under fast magic angle spinning.
PubMed:
Refolding SDS-denatured proteins by the addition of amphipathic cosolvents.
PubMed:
High-resolution solid-state MAS NMR of proteins-Crh as an example.
PubMed:
The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: a novel homodimer assembling and the implication for effector-binding mode.
PubMed:
Aqueous self-assembly of phytantriol in ternary systems: effect of monoolein, distearoylphosphatidylglycerol and three water-miscible solvents.
PubMed:
Isolation of Arabidopsis nuclei and measurement of gene transcription rates using nuclear run-on assays.
PubMed:
A family of nanoporous materials based on an amino acid backbone.
PubMed:
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1.
PubMed:
Preferential hydration of DNA: the magnitude and distance dependence of alcohol and polyol interactions.
PubMed:
Effect of organic cosolvents on the free solution mobility of curved and normal DNA molecules.
PubMed:
Atomic force microscopy of native human metaphase chromosomes in a liquid.
PubMed:
Effect of the solvent on the conformation of a depsipeptide: NMR-derived solution structure of hormaomycin in DMSO from residual dipolar couplings in a novel DMSO-compatible alignment medium.
PubMed:
Pentane-1,5-diol as a percutaneous absorption enhancer.
PubMed:
Polar body formation in Spisula oocytes: function of the peripheral aster.
PubMed:
Induction of cytokinesis is independent of precisely regulated microtubule dynamics.
PubMed:
A new arrangement of (beta/alpha)8 barrels in the synthase subunit of PLP synthase.
PubMed:
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles.
PubMed:
Crystalization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus.
PubMed:
A redetermination of the structure of the triple mutant (K53,56,120M) of phospholipase A2 at 1.6 A resolution using sulfur-SAS at 1.54 A wavelength.
PubMed:
Exclusion of alcohols from spermidine-DNA assemblies: probing the physical basis of preferential hydration.
PubMed:
Characteristics of migration patterns of DNA oligomers in gels and the relationship to the question of intrinsic DNA bending.
PubMed:
Microtubule plus-end dynamics in Xenopus egg extract spindles.
PubMed:
The OH-initiated oxidation of hexylene glycol and diacetone alcohol.
PubMed:
Increased temperature and 2-methyl-2,4-pentanediol change the DNA structure of both curved and uncurved adenine/thymine-rich sequences.
PubMed:
Development of indomethacin Carbopol ETD 2001 gels and the influence of storage time and temperature on their stability.
PubMed:
The crystal structure and stereospecificity of levodione reductase from Corynebacterium aquaticum M-13.
PubMed:
Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
PubMed:
Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels.
PubMed:
An overview on 2-methyl-2,4-pentanediol in crystallization and in crystals of biological macromolecules.
PubMed:
Determination of glycols in biological specimens by gas chromatography-mass spectrometry.
PubMed:
Pluronic F-127 gels as a vehicle for topical formulations of indomethacin and rheological behaviour of these formulations.
PubMed:
KNI-272, a highly selective and potent peptidic HIV protease inhibitor.
PubMed:
The 1.19 A X-ray structure of 2'-O-Me(CGCGCG)(2) duplex shows dehydrated RNA with 2-methyl-2,4-pentanediol in the minor groove.
PubMed:
An open study of efficacy and safety of long-term treatment with mometasone furoate fatty cream in the treatment of adult patients with atopic dermatitis.
PubMed:
Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD.
PubMed:
Bivariate flow cytometry DNA/BrdUrd analysis of plant cell cycle.
PubMed:
Crystallographic studies on a family B DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis strain KOD1.
PubMed:
Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure.
PubMed:
Non-flammable preparative reversed-phase liquid chromatography of recombinant human insulin-like growth factor-I.
PubMed:
Division of polar bodies induced by their enlargement in the starfish Asterina pectinifera.
PubMed:
Effects of neutral salts on RNA chain elongation and pausing by Escherichia coli RNA polymerase.
PubMed:
Effect of the crystallizing agent 2-methyl-2,4-pentanediol on the structure of adenine tract DNA in solution.
PubMed:
Comparison of the solution and crystal conformations of (G + C)-rich fragments of DNA.
PubMed:
The organic crystallizing agent 2-methyl-2,4-pentanediol reduces DNA curvature by means of structural changes in A-tracts.
PubMed:
Cosolvent-induced adsorption and desorption of serum proteins on an amphiphilic mercaptomethylene pyridine-derivatized agarose gel.
PubMed:
MPD and DNA bending in crystals and in solution.
PubMed:
What is the basis of sequence-directed curvature in DNAs containing A tracts?
PubMed:
Dehydrating agents sharply reduce curvature in DNAs containing A tracts.
PubMed:
Contribution of the surface free energy perturbation to protein-solvent interactions.
PubMed:
High resolution structures of the 4-4-20 Fab-fluorescein complex in two solvent systems: effects of solvent on structure and antigen-binding affinity.
PubMed:
High resolution detection of uncoated metaphase chromosomes by means of field emission scanning electron microscopy.
PubMed:
Effect of hexylene glycol-altered microtubule distributions on cytokinesis and polar lobe formation in fertilized eggs of Ilyanassa obsoleta.
PubMed:
Cosolvent modulation of the tubulin-colchicine GTPase-activating conformational change: strength of the enzymatic activity.
PubMed:
Further evaluation of a new penetration enhancer, HPE-101.
PubMed:
The alpha-helical content of calmodulin is increased by solution conditions favouring protein crystallisation.
PubMed:
A high-yield procedure for isolation of metaphase chromosomes from root tips of Vicia faba L.
PubMed:
Conditions for assembly of tubulin-based structures in unfertilized sea urchin eggs. Spirals, monasters and cytasters.
PubMed:
The ultrastructure of Pityrosporum pachydermatis.
PubMed:
Preparation and flow cytometric analysis of metaphase chromosomes of tomato.
PubMed:
Change in the heterogeneous distribution of tubulin isotypes in mitotic microtubules of the sea urchin egg by treatment with microtubule depolymerizing or stabilizing drugs.
PubMed:
Antibacterial and antifungal properties of propylene glycol, hexylene glycol, and 1,3-butylene glycol in vitro.
PubMed:
Crystal structure of thioredoxin from Escherichia coli at 1.68 A resolution.
PubMed:
[Effect of hexylene glycol on microtubular structures in starfish oocytes and sea urchin eggs].
PubMed:
Skin reactions to hexylene glycol.
PubMed:
Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol.
PubMed:
The genetic toxicology of some hydrocarbon and oxygenated solvents.
PubMed:
Differences in crystal properties and ligand affinities of an antifluorescyl Fab (4-4-20) in two solvent systems.
PubMed:
Phase diagrams for DNA crystallization systems.
PubMed:
[The use of phase diagrams in the crystallization of oligonucleotide duplexes. I. A model of crystallization of the (pGpT)n.(pApC)n + spermine system].
PubMed:
Single crystals of hydrogenase from Desulfovibrio vulgaris Miyazaki F.
PubMed:
Cytoskeleton of the unfertilized sea urchin egg.
PubMed:
Oxygen consumption by tumor cells during membrane vesicle shedding.
PubMed:
Dual effect of procaine in sea urchin eggs. Inducer and inhibitor of microtubule assembly.
PubMed:
Effect of a nonsteroidal antiandrogen, flutamide, on androgen receptor dynamics and ornithine decarboxylase gene expression in mouse kidney.
PubMed:
Nuclear androgen receptors in different stages of the seminiferous epithelial cycle and the interstitial tissue of rat testis.
PubMed:
Nonaqueous fractionation of HeLa cells in glycols.
PubMed:
Composition of the isolated mitotic apparatus: analysis by polyacrylamide gel electrophoresis.
PubMed:
[Study of a lysis medium stabilizing microfilaments and microtubules in vitro and in vivo].
PubMed:
Structure of variant-3 scorpion neurotoxin from Centruroides sculpturatus Ewing, refined at 1.8 A resolution.
PubMed:
Localization of estrogen receptor regulatory factor in the uterine nucleus.
PubMed:
Selective crystallization of horse isoferritins.
PubMed:
Chinese hamster metaphase chromosomes isolated under physiological conditions. A partial characterization of associated non-histone proteins and protein cores.
PubMed:
Possible role of microtubules in tumor cell surface membrane shedding, permeability, and lympholysis.
PubMed:
Preparation of calmodulin crystals.
PubMed:
Stereo electron microscope studies of mitotic chromosomes from Chinese hamster ovary cells.
PubMed:
Safety evaluation of some humectants and moisturizers used in cosmetic formulations.
PubMed:
Parthenogenetic activation of sea urchin egg induces a cyclical variation of the cytoplasmic resistance to hexylene glycol-Triton X-100 treatment.
PubMed:
Six polymorphic crystal forms of alpha-cobratoxin.
PubMed:
A new method for the preparation of metaphase chromosomes for flow analysis.
PubMed:
Packing DNA into chromosomes.
PubMed:
Experimental determinations of tubulin in the in vivo mitotic apparatus of sea urchin zygotes.
PubMed:
An analysis of spindle ultrastructure during prometaphase and metaphase of micronuclear division in Tetrahymena.
PubMed:
Induction of cleavage in nucleated and enucleated frog eggs by injection of isolated sea-urchin mitotic apparatus.
PubMed:
Studies on the de novo formation of centrioles: aster formation in the activated eggs of sea urchin.
PubMed:
Cytochemical and ultrastructural studies on the synaptonemal complex of rat spermatocytes.
PubMed:
Isolation of nuclei using hexylene glycol.
PubMed:
Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components.
PubMed:
The effect of vinblastine, colchicine and hexylene glycol on migration of human monocytes.
PubMed:
Spindle birefringence of isolated mitotic apparatus analysed by pressure treatment.
PubMed:
Studies on intracellular transport of secretory proteins in the rat exocrine pancreas. II. Inhibition of antimicrotubular agents.
PubMed:
The avian erythrocyte: a study of fixation for electron microscopy.
PubMed:
Colchicine-binding protein and the secretion of thyroid hormone.
PubMed:
Electron probe analysis of freeze-substituted, epoxy resin embedded tissue for ion transport studies in plants.
PubMed:
Purification of intact microtubules from brain.
PubMed:
The mitotic apparatus. Physical chemical characterization of the 22S protein component and its subunits.
PubMed:
The mitotic apparatus. Identification of the major soluble component of the glycol-isolated mitotic apparatus.
PubMed:
The toxicity of 2-methylpentan-2, 4-diol (hexylene glycol) by chronic oral administration to rats and mice.
PubMed:
The excretion of hexylene glycol (2-methyl-2,4-pentane diol) in man.
PubMed:
Determination of 2-methyl-2,4-pentane diol (hexylene glycol) in the urine of man and rats.
PubMed:
Local and systemic effects of 2-methyl 2,4 pentanediol (hexylene glycol).