retinyl linoleate
retinol, 9,12-octadecadienoate, (Z,Z)-
Identification
| Name | retinyl linoleate |
| IUPAC | [(2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] (9Z,12Z)-octadeca-9,12-dienoate |
| CAS Number | 631-89-0 |
| FDA UNII | 61911N8D6W |
| Molecular Formula | C38 H60 O2 |
| Molecular Weight | 548.89460000 |
| XlogP3 | 13.00 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 630.97 °C. @ 760.00 mm Hg (est) |
| Flash Point | 173.00 °F. TCC ( 78.40 °C. ) (est) |
| logP (o/w) | 14.529 (est) |
| Soluble in | water, 6.7e-012 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for retinyl linoleate usage levels up to | not for fragrance use. |
| Recommendation for retinyl linoleate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
[(2Z,4E,6Z,8E)-3,7-
dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] (9Z,12Z)-octadeca-9,12-dienoate
nikkol VA-LINO
retinol linoleate
retinol, 9,12-octadecadienoate, (Z,Z)-
PubMed:
An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion, and vitamin A status in humans.
PubMed:
Effect of vitamin A deficiency on retinol and retinyl esters contents in rat brain.
PubMed:
Effects of maternal dietary supplementation with three sources of carotenoids on the retinyl esters of egg yolk and developing quail liver.
PubMed:
Effects of dietary taurocholate, fat and protein on the storage and metabolism of dietary beta-carotene and alpha-tocopherol in ferrets.
PubMed:
Amounts and types of fatty acids in meals affect the pattern of retinoids secreted in human chylomicrons after a high-dose preformed vitamin A intake.
PubMed:
Antioxidant systems of the developing quail embryo are compromised by mycotoxin aurofusarin.
PubMed:
Determination of retinol and retinyl esters in human plasma by high-performance liquid chromatography with automated column switching and ultraviolet detection.
PubMed:
Comparison of the postprandial plasma vitamin A response in young and older adults.
PubMed:
Dietary triglycerides, up to 40 g/meal, do not affect preformed vitamin A bioavailability in humans.
PubMed:
High concentrations of vitamin A esters circulate primarily as retinyl stearate and are stored primarily as retinyl palmitate in ferret tissues.
PubMed:
Quantitative plasma disposition of retinol and retinyl esters after high-dose oral vitamin A administration in the cynomolgus monkey.
PubMed:
Esterification of retinol in lacrimal gland. Evidence for acyl-CoA:retinol acyltransferase activity.
PubMed:
Retinyl ester (vitamin A ester) and carotenoid composition in human liver.
PubMed:
Retinol esterification in Sertoli cells by lecithin-retinol acyltransferase.
PubMed:
Vitamin A is stored as fatty acyl esters of retinol in the lacrimal gland.
PubMed:
Influence of dietary retinyl acetate on normal rat mammary gland development and on the enhancement of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumorigenesis by high levels of dietary fat.
PubMed:
Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications.
PubMed:
Effect of dietary essential fatty acids on vitamin A utilization in the rat.