cetyl palmitate
palmityl palmitate
Identification
| Name | cetyl palmitate |
| IUPAC | hexadecyl hexadecanoate |
| CAS Number | 100231-74-1 |
| EINECS | 309-375-8 |
| FDA UNII | 5ZA2S6B08X |
| Molecular Formula | C32 H64 O2 |
| Molecular Weight | 480.86048000 |
| Nikkaji Number | J65.556B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 507.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 518.00 °F. TCC ( 269.80 °C. ) (est) |
| logP (o/w) | 15.590 (est) |
| Soluble in | water, 3.134e-010 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cetyl palmitate usage levels up to | not for fragrance use. |
| Recommendation for cetyl palmitate flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
hexadecyl hexadecanoate
hexadecyl palmitate
palmityl palmitate
PubMed:
Formulation of solid lipid nanoparticles (SLN): The value of different alkyl polyglucoside surfactants.
PubMed:
Idebenone loaded solid lipid nanoparticles: calorimetric studies on surfactant and drug loading effects.
PubMed:
FA-loaded lipid drug delivery systems: preparation, characterization and biological studies.
PubMed:
Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation.
PubMed:
Improved brain delivery of vincristine using dextran sulfate complex solid lipid nanoparticles: optimization and in vivo evaluation.
PubMed:
Modeling the effect of sonication parameters on size and dispersion temperature of solid lipid nanoparticles (SLNs) by response surface methodology (RSM).
PubMed:
All-trans retinoic acid-loaded lipid nanoparticles as a transdermal drug delivery carrier.
PubMed:
Lipid nanoparticles based on butyl-methoxydibenzoylmethane: in vitro UVA blocking effect.
PubMed:
Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation.
PubMed:
In vitro evaluation on a model of blood brain barrier of idebenone-loaded solid lipid nanoparticles.
PubMed:
Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway.
PubMed:
Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting.
PubMed:
Multivariate design for the evaluation of lipid and surfactant composition effect for optimisation of lipid nanoparticles.
PubMed:
Preparation and optimization of PIT solid lipid nanoparticles via statistical factorial design.
PubMed:
Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles.
PubMed:
Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size.
PubMed:
Nanostructured lipid carriers (NLC) for parenteral delivery of an anticancer drug.
PubMed:
Development and validation of a simple reversed-phase HPLC method for the determination of camptothecin in animal organs following administration in solid lipid nanoparticles.
PubMed:
In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios.
PubMed:
Dissolution of solid lipid extrudates in biorelevant media.
PubMed:
Hydrophilic coating of mitotane-loaded lipid nanoparticles: preliminary studies for mucosal adhesion.
PubMed:
Lipid nanoparticles for brain targeting I. Formulation optimization.
PubMed:
Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies.
PubMed:
Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice.
PubMed:
Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): effects on size, physical stability and particle matrix structure.
PubMed:
In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain.
PubMed:
Cationic solid lipid nanoparticles loaded by cysteine proteinase genes as a novel anti-leishmaniasis DNA vaccine delivery system: characterization and in vitro evaluations.
PubMed:
Physicochemical characterization and in vivo bioluminescence imaging of nanostructured lipid carriers for targeting the brain: apomorphine as a model drug.
PubMed:
The influence of lipid characteristics on the formation, in vitro release, and in vivo absorption of protein-loaded SLN prepared by the double emulsion process.
PubMed:
Preparation, optimization and characteristic of huperzine a loaded nanostructured lipid carriers.
PubMed:
Nondestructive rheological measurement of aqueous dispersions of solid lipid nanoparticles: effects of lipid types and concentrations on dispersion consistency.
PubMed:
Chemical and structural investigation of lipid nanoparticles: drug-lipid interaction and molecular distribution.
PubMed:
Corticosteroid solubility and lipid polarity control release from solid lipid nanoparticles.
PubMed:
Lipid nanoparticles with different oil/fatty ester ratios as carriers of buprenorphine and its prodrugs for injection.
PubMed:
Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC.
PubMed:
In vitro skin permeation of sunscreen agents from O/W emulsions.
PubMed:
The effect of cetyl palmitate crystallinity on physical properties of gamma-oryzanol encapsulated in solid lipid nanoparticles.
PubMed:
Oral insulin delivery by means of solid lipid nanoparticles.
PubMed:
Cetyl palmitate-based NLC for topical delivery of Coenzyme Q(10) - development, physicochemical characterization and in vitro release studies.
PubMed:
Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics.
PubMed:
A water activity control system for enzymatic reactions in organic media.
PubMed:
Solid lipid nanoparticles (SLN)--effects of lipid composition on in vitro degradation and in vivo toxicity.
PubMed:
Preparation and characterization of n-dodecyl-ferulate-loaded solid lipid nanoparticles (SLN).
PubMed:
Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique.
PubMed:
The development of Cutina lipogels and gel microemulsion for topical administration of fluconazole.
PubMed:
Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties.
PubMed:
Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers.
PubMed:
Bioavailability of diazepam from aqueous-organic solution, submicron emulsion and solid lipid nanoparticles after rectal administration in rabbits.
PubMed:
Encapsulation of retinoids in solid lipid nanoparticles (SLN).
PubMed:
Preserved solid lipid nanoparticles (SLN) at low concentrations do cause neither direct nor indirect cytotoxic effects in peritoneal macrophages.
PubMed:
Comparison of wax and glyceride solid lipid nanoparticles (SLN).
PubMed:
Crystallographic investigation of cetylpalmitate solid lipid nanoparticles.
PubMed:
Solid lipid nanoparticles (SLN/Lipopearls)--a pharmaceutical and cosmetic carrier for the application of vitamin E in dermal products.
PubMed:
Spray-drying of solid lipid nanoparticles (SLN TM).
PubMed:
Effect of topical preparation of mycophenolic acid on experimental allergic contact dermatitis of guinea-pigs induced by dinitrofluorobenzene.
PubMed:
The esterase profile of a lipase from Candida cylindracea.
PubMed:
Growth of Acinetobacter sp. strain HO1-N on n-hexadecanol: physiological and ultrastructural characteristics.
PubMed:
Collaborative study of a GLC method for vitamin E.
PubMed:
[Aqueous petroleum-oxidizing Arthrobacter].
PubMed:
[Formation of cetyl palmitate from n-hexadecane by Mycobacterium strain 3' cultures].
PubMed:
ORIGIN OF PALMITIC ACID CARBON IN PALMITATES FORMED FROM HEXADECANE-1-C-14 AND TETRADECANE-1-C-14 BY MICROCOCCUS CERIFICANS.