botryodiplodin
2-hydroxy-3-methyl-4-acetyltetrahydrofuran
Identification
| Name | botryodiplodin |
| IUPAC | 1-(5-hydroxy-4-methyloxolan-3-yl)ethanone |
| CAS Number | 27098-03-9 |
| FDA UNII | 5G35Q22R8M |
| Molecular Formula | C7 H12 O3 |
| Molecular Weight | 144.17024000 |
| Nikkaji Number | J16.997H |
| Beilstein | 2935786 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 249.36 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.004000 mmHg @ 25.00 °C. (est) |
| Flash Point | 214.00 °F. TCC ( 101.40 °C. ) (est) |
| logP (o/w) | 0.571 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | unreported-mouse LD50 40 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for botryodiplodin usage levels up to | not for fragrance use. |
| Recommendation for botryodiplodin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
antibiotic PSX 1
botrydiplodin
botryodipolodin
botyrodiplodin
cytostipin
ethanone, 1-(tetrahydro-5-hydroxy-4-methyl-3-furanyl)- (9CI)
2-
hydroxy-3-methyl-4-acetyl tetrahydrofuran
2-
hydroxy-3-methyl-4-acetyltetrahydrofuran
2-
hydroxy-3-methyl-4-acetyltetrahydrofurane
1-(5-
hydroxy-4-methyloxolan-3-yl)ethanone
ketone, methyl tetrahydro-5-hydroxy-4-methyl-3-furyl
methyltetrahydro-5-hydroxy-4-methyl-3-furyl-ketone
1-(
tetrahydro-5-hydroxy-4-methyl-3-furanyl)ethanone
PubMed:
Lasiojasmonates A-C, three jasmonic acid esters produced by Lasiodiplodia sp., a grapevine pathogen.
PubMed:
Isolation and structural elucidation of eight new related analogues of the mycotoxin (-)-botryodiplodin from Penicillium coalescens.
PubMed:
Soybean charcoal rot disease fungus Macrophomina phaseolina in Mississippi produces the phytotoxin (-)-botryodiplodin but no detectable phaseolinone.
PubMed:
Acyclic Stereoselection in the Ortho Ester Claisen Rearrangement.
PubMed:
The antibiotic PSX-1 produced by Penicillium stipitatum is identical with botryodiplodin.
PubMed:
Absence of DNA breaks during repair of DNA-protein cross-links induced by the mycotoxin botryodiplodin in mammalian cells.
PubMed:
Repair of DNA-protein cross-links induced by the mycotoxin botryodiplodin in mammalian cells.
PubMed:
DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells.
PubMed:
Relationships between the biological effects and chemical structure of the genotoxic mycotoxin, botryodiplodin.
PubMed:
Effects of the mycotoxin botryodiplodin on mammalian cells in culture.
PubMed:
Mutagenicity of the mycotoxin botryodiplodin in the Salmonella typhimurium/microsomal activation test.
PubMed:
[Toxicological study on the metabolites of Penicillium carneo-lutescens].
PubMed:
Immunosuppressive properties of the antibiotics cytostipin and vermiculine.
PubMed:
Stereochemistry and synthesis of the antileukemic agent botryodiplodin.
PubMed:
Botryodiplodin--a new antibiotic from Botryodiplodia theobromae. II. Production, isolation and biological properties.